Course Title Code Semester L+P Hour Credits ECTS
Introduction to Pharmaceutical Chemistry * ECF   215 3 2 2 3

Prerequisites and co-requisites
Recommended Optional Programme Components None

Language of Instruction Turkish
Course Level First Cycle Programmes (Bachelor's Degree)
Course Type
Course Coordinator Asst.Prof.Dr. Özden TARI
Dr. Öğr. ÜyesiÖZDEN TARI1. Öğretim Grup:A
The general aim of this course is to introduce the pharmaceutical chemistry course to the students; to inform the students about the difficulties / complexity and stages of drug design and methods to discover of lead compound; the steps and the procedures of rational drug design, computer aided/assisted drug design; molecular modification methods and quantitative structure-activity reletionship studies for the optimization of lead compound.
Course content is the basic concepts of pharmaceutical chemistry, procedures and methods of.drug design and new drug development.

Learning Outcomes

Course's Contribution To Program
NoProgram Learning OutcomesContribution

Course Content
WeekTopicsStudy Materials _ocw_rs_drs_yontem
1 Pharmaceutical chemistry / medicinal chemistry: definitions, historical development, classification of drugs and medicines Textbooks
2 Drug and organism: pharmacodynamic and pharmacokinetic principles, structure-specific and non-nonspecific drugs Textbooks
3 Receptors and drug-receptor interactions Textbooks
4 Stereochemical factors and importance on activity; Isosterism and bioisosterism Textbooks
5 Structure-activity relationships Textbooks
6 Quantitative structure-activity relationships Textbooks
7 Metabolism of Drugs Textbooks
8 Mid-Term Exam Textbooks
9 Mid-Term Exam Evaluation-Metabolism of Drugs Textbooks
10 Drug design and new drug development, stages of drug development Textbooks
11 Precursor compound, Methods of finding the precursor compound Textbooks
12 Rational drug design, drug-target interaction, elucidation of target structure Textbooks
13 Rational drug design steps, the methods used Textbooks
14 Computer-Aided Drug Design Methods: Ligand-Based Approaches Textbooks
15 Computer-Aided Drug Design Methods: Structure-Based Approaches Textbooks
16-17 Term Exams Textbooks

Recommended or Required Reading
Additional Resources