COURSE INFORMATON
Course Title Code Semester L+P Hour Credits ECTS
Biochemical Toxicology * BL   442 8 2 2 4

Prerequisites and co-requisites Yok
Recommended Optional Programme Components None

Language of Instruction Turkish
Course Level First Cycle Programmes (Bachelor's Degree)
Course Type
Course Coordinator Prof.Dr. Elif ORUÇ
Instructors
Prof.Dr.MEHMET İSKENDER EMRE1. Öğretim Grup:A
 
Assistants
Goals
The aim of this course is to provıde knowledge and understanding about the principles of toxicology, xenobiotic metabolism. Also it will be discussed on cell damage together with biochemical and molecular toxicity mechanisms of xenobiotics.
Content
Principles of toxicology, toxic effect mechanisms of xenobiotics, cell damage and protective mechanisms

Learning Outcomes
-


Course's Contribution To Program
NoProgram Learning OutcomesContribution
12345
1
Explain the basic concepts and principles in biology
X
2
The knowledge gained in the field of biology combine with information from other sciences.
X
3
Identifies problems in the field of biology and apply methods for their solution
X
4
Describes the method of producing scientific knowledge in the field of biology
X
5
They will receive information on the biology area, in order to classify it uses and purposes.
X
6
They use advanced theoretical and practical knowledge that obtain in biology field.
X
7
They are Field-related issues can inform the relevant persons and institutions, They share ideas and problems relating to suggestions as the written, oral and Visual to expert or transfer to non-experts.
X
8
They can take responsibility as individuals and team members to solve unpredictable problems encountered in applications related to the field.
X
9
they can take an active role as a member of the execution team the planning of projects related to the field.
X
10
They know that life-long learning process and act accordingly.
X
11
They will increase the knowledge and experience outside major issues with specific elective courses in different fields of biology.
X
12
They speak English enough to communicate with colleagues to understand the basic concepts of biology.
X
13
They both with colleagues, as well as areas with non-person establishes ethical uses of information and communication technology. In addition to professional development, in line with the interests and abilities of scientific, social, constantly improves
X
14
They assesses developments in biology versatile using scientific methods and techniques
X
15
They know the importance of personal development and enforces the need.
X

Course Content
WeekTopicsStudy Materials _ocw_rs_drs_yontem
1 Introduction to biochemical toxicology Review of the relevant pages from sources
2 Absorption, distribution, metabolism, side of action and excretion Review of the relevant pages from sources
3 Molecular techniques in toxicology Review of the relevant pages from sources
4 Phase I metabolism and pharmacogenetic Review of the relevant pages from sources
5 Conjugation and elimination of toxic substances Review of the relevant pages from sources
6 Physiological factors affecting xenobiotic metabolism Review of the relevant pages from sources
7 Adaptation to toxicants Review of the relevant pages from sources
8 Mid-term exam Mid-term exam
9 Cell injury and cellular protection mechanism Review of the relevant pages from sources
10 Reactive metabolites and toxicity Review of the relevant pages from sources
11 Central nervous system Review of the relevant pages from sources
12 Neurodegenerative disseas neurotoxicity mechanisms Review of the relevant pages from sources
13 Hepatotoxicity Review of the relevant pages from sources
14 Nutritinal Factors Review of the relevant pages from sources
15 Reproductive toxicology Review of the relevant pages from sources
16-17 Final exam Final exam

Recommended or Required Reading
Textbook
Additional Resources