TÜRKÇE
ENGLISH
Information
| Unit | FACULTY OF PHARMACY |
| PHARMACY PR. | |
| Code | ECF211 |
| Name | Biochemistry I |
| Term | 2017-2018 Academic Year |
| Semester | 3. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Label | C Compulsory |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. ÖZLEM ALPTEKİN |
| Course Instructor |
Doç. Dr. ÖZLEM ALPTEKİN
(Güz)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Understanding the basic knowledge of biomolecules in living systems, comprehending structure, function and functions of biomolecules in organism, genetic information storage, transfer and regulation of gene expression.
Course Content
Informations about the foundations of biochemistry, water, amino acids, peptides and proteins, the three-dimensional structure of proteins, protein function, enzymes and their kinetics, carbohydrates and glycobiology, nucleotides and nucleic acids, DNA-based information technologies, lipids, biological membranes and transport and biosignaling will be given in this lesson.
Course Precondition
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | She/He explains the cellular, chemical, physical, genetic and evolutionary foundations. |
| LO02 | She/He explains the effect of pH on solubility in biological systems. |
| LO03 | She/He explains the importance of water in life. |
| LO04 | She/He calculates the net charge of an amino acid based on the ambient pH. |
| LO05 | She/He can give examples of amyloidosis caused by defects in protein folding. |
| LO06 | She/He explains the structures of myoglobin, α-creatine and collagen proteins. |
| LO07 | She/He explains the positive and negative cooperative relationship between protein ligand. |
| LO08 | She/He associates sickle cell anemia with a change in the primary structure of hemoglobin. |
| LO09 | She/He explains the key-lock hypothesis and stimulated-fit model in enzyme activity. |
| LO10 | She/He infers Michaelis-Menten kinetics in enzyme kinetics. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 2 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 2 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 2 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | 4 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | 3 |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | The Foundations of Biochemistry | Textbooks and internet | |
| 2 | Water | Textbooks and internet | |
| 3 | Amino Acids, Peptides and Proteins | Textbooks and internet | |
| 4 | The Three-Dimensional Structure Of Proteins | Textbooks and internet | |
| 5 | Protein Function | Textbooks and internet | |
| 6 | Enzymes | Textbooks and internet | |
| 7 | Enzymes and their kinetics | Textbooks and internet | |
| 8 | Mid-Term Exam | Written exam | |
| 9 | Carbohydrates And Glycobiology | Textbooks and internet | |
| 10 | Nucleotides and Nucleic Acids | Textbooks and internet | |
| 11 | DNA-Based Information Technologies | Textbooks and internet | |
| 12 | Lipids | Textbooks and internet | |
| 13 | Biological Membranes and Transport | Textbooks and internet | |
| 14 | Biosignaling | Textbooks and internet | |
| 15 | Signal-Transduction Pathways | Textbooks and internet | |
| 16 | Term Exams | Written exam | |
| 17 | Term Exams | Written exam |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Midterm Exam | 38 | 15.2 |
| 2. Midterm Exam | 38 | 15.2 |
| 1. Homework | 24 | 9.6 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 78 | ||
| Total Workload / 25 (h) | 3,12 | ||
| ECTS | 3 ECTS | ||