TÜRKÇE
ENGLISH
Information
| Unit | FACULTY OF PHARMACY |
| PHARMACY PR. | |
| Code | ECF215 |
| Name | Introduction to Pharmaceutical Chemistry |
| Term | 2017-2018 Academic Year |
| Semester | 3. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Label | C Compulsory |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi ÖZDEN TARI |
| Course Instructor |
Dr. Öğr. Üyesi ÖZDEN TARI
(Güz)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
The general aim of this course is to introduce the pharmaceutical chemistry course to the students; to inform the students about the difficulties / complexity and stages of drug design and methods to discover of lead compound; the steps and the procedures of rational drug design, computer aided/assisted drug design; molecular modification methods and quantitative structure-activity reletionship studies for the optimization of lead compound.
Course Content
Course content is the basic concepts of pharmaceutical chemistry, procedures and methods of.drug design and new drug development.
Course Precondition
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Pharmaceutical chemistry / medicinal chemistry: definitions, historical development, classification of drugs and medicines | Textbooks | |
| 2 | Drug and organism: pharmacodynamic and pharmacokinetic principles, structure-specific and non-nonspecific drugs | Textbooks | |
| 3 | Receptors and drug-receptor interactions | Textbooks | |
| 4 | Stereochemical factors and importance on activity; Isosterism and bioisosterism | Textbooks | |
| 5 | Structure-activity relationships | Textbooks | |
| 6 | Quantitative structure-activity relationships | Textbooks | |
| 7 | Metabolism of Drugs | Textbooks | |
| 8 | Mid-Term Exam | Textbooks | |
| 9 | Mid-Term Exam Evaluation-Metabolism of Drugs | Textbooks | |
| 10 | Drug design and new drug development, stages of drug development | Textbooks | |
| 11 | Precursor compound, Methods of finding the precursor compound | Textbooks | |
| 12 | Rational drug design, drug-target interaction, elucidation of target structure | Textbooks | |
| 13 | Rational drug design steps, the methods used | Textbooks | |
| 14 | Computer-Aided Drug Design Methods: Ligand-Based Approaches | Textbooks | |
| 15 | Computer-Aided Drug Design Methods: Structure-Based Approaches | Textbooks | |
| 16 | Term Exams | Textbooks | |
| 17 | Term Exams | Textbooks |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Midterm Exam | 50 | 20 |
| 2. Midterm Exam | 50 | 20 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |