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Information
| Unit | FACULTY OF SCIENCE AND LETTERS |
| BIOLOGY PR. | |
| Code | BL310 |
| Name | Molecular Biology |
| Term | 2017-2018 Academic Year |
| Semester | 6. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Label | C Compulsory |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. BURHAN ARIKAN |
| Course Instructor |
Prof. Dr. BURHAN ARIKAN
(Bahar)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Lerning of macromoleculs structures, DNA analysis, DNA repair systems, proteomic, genomic, antisens oligonucleotids, molecular diagnostics
Course Content
Structure and replication of DNA, DNA repcilation enzymes, DNA sequencing, Resctriction endonuclease enzymes, protein isolation techniques and prufication, Techniques of DNA and protein analyses (Agarose gel electrophoresis, PAGE, Isoelectric focusing, two dimensional electrophoresis, gradient PAGE), DNA repair mechanisms (SOS, excision, photoreactivation, post replicative repair), proteomic, genomic, gene therapy, antisense oligonucleotide therapy, recombinant vaccines (Recombinant DNA and viral vaccines)
Course Precondition
BL 310 Moleküler Biyoloji
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explain DNA replication and types of replication |
| LO02 | Explains the molecular basis of DNA replication |
| LO03 | Categorize protein isolation techniques and purifications |
| LO04 | Explains molecular typing methods (DNA fingerprint, RFLP, RAPD) |
| LO05 | Proteomic, Genomic and gene theraphy |
| LO06 | Explains DNA repair mechanisms (SOS, Excision, Photoreactivation, Post replicative repair) |
| LO07 | Discusses antisense oligonucleotide technology |
| LO08 | Categorizes PAGE, SDS-PAGE, Two-dimensional PAGE, Capillary electrophoresis, Isoelectric focusing, Immunoelectrophoresis |
| LO09 | Antisense oligonucleotide technology explains |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explain the basic concepts and principles in biology | |
| PLO02 | Bilgi - Kuramsal, Olgusal | The knowledge gained in the field of biology combine with information from other sciences. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Identifies problems in the field of biology and apply methods for their solution | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Describes the method of producing scientific knowledge in the field of biology | 2 |
| PLO05 | Bilgi - Kuramsal, Olgusal | They will receive information on the biology area, in order to classify it uses and purposes. | |
| PLO06 | Bilgi - Kuramsal, Olgusal | They use advanced theoretical and practical knowledge that obtain in biology field. | 3 |
| PLO07 | Bilgi - Kuramsal, Olgusal | They are Field-related issues can inform the relevant persons and institutions, They share ideas and problems relating to suggestions as the written, oral and Visual to expert or transfer to non-experts. | |
| PLO08 | Bilgi - Kuramsal, Olgusal | They can take responsibility as individuals and team members to solve unpredictable problems encountered in applications related to the field. | |
| PLO09 | Bilgi - Kuramsal, Olgusal | they can take an active role as a member of the execution team the planning of projects related to the field. | 2 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | They know that life-long learning process and act accordingly. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They will increase the knowledge and experience outside major issues with specific elective courses in different fields of biology. | |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They speak English enough to communicate with colleagues to understand the basic concepts of biology. | 2 |
| PLO13 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They both with colleagues, as well as areas with non-person establishes ethical uses of information and communication technology. In addition to professional development, in line with the interests and abilities of scientific, social, constantly improves itself by identifying learning needs in cultural and artistic fields. | |
| PLO14 | Yetkinlikler - Öğrenme Yetkinliği | They assesses developments in biology versatile using scientific methods and techniques | |
| PLO15 | Yetkinlikler - Öğrenme Yetkinliği | They know the importance of personal development and enforces the need. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | DNA replication and replication type | Study in literature | |
| 2 | Molecular content of DNA replications | Study in literature | |
| 3 | DNA repcilation enzymes | Study in literature | |
| 4 | DNA sequencing | Study in literature | |
| 5 | Resctriction endonuclease enzymes | Study in literature | |
| 6 | Protein isolation techniques and prufication | Study in literature | |
| 7 | PAGE, SDS-PAGE, two dimensional PAGE, İsoelectric focusing, Immunelectrophoresis | ||
| 8 | Exam | Study in literature | |
| 9 | DNA repair mechanisms (SOS, Exiition, Photoreactivation, Post replicatice repair) | Study in literature | |
| 10 | Antisence oligonucleotide techniques | Study in literature | |
| 11 | Recombinant DNA vaccines | Study in literature | |
| 12 | Recombinant virus vaccines | Study in literature | |
| 13 | Molecular identification techniques (DNA fingerprint, RFLP, RAPD) | Study in literature | |
| 14 | Proteomic, Genomic and gene theraphy | Study in literature | |
| 15 | DNA and protein anaysis techniques (Starch, cellulosa asetate, agarose gel electrophoresis) | Study in literature | |
| 16 | Final exam | ||
| 17 | Final exam |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Midterm Exam | 100 | 40 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 13 | 13 |
| Total Workload (Hour) | 75 | ||
| Total Workload / 25 (h) | 3,00 | ||
| ECTS | 3 ECTS | ||