TÜRKÇE
ENGLISH
Information
| Unit | INSTITUTE OF NATURAL AND APPLIED SCIENCES |
| BIOTECHNOLOGY (MASTER) (WITH THESIS) (INTERDISCIPLINARY) | |
| Code | BT039 |
| Name | Introduction to Protein Chemistry |
| Term | 2018-2019 Academic Year |
| Term | Spring |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. ŞULE SULTAN MENZİLETOĞLU YILDIZ |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
The relationship between protein structure and function and factors affecting protein function, protein isolation, purification and structure
Course Content
General Properties of Protein Structure, Amino Acids, Primary Structure, Secondary Structure, Secondary Structure, Quaternary Structure, Purification and Characterization of Proteins, Structural Analysis of Proteins, Determination of Protein Structure by X-Ray Diffraction, Biological Functions of Proteins, Enzymes, Hemoglobin, Myoglobin, Cell Skeleton Proteins, Immunoproteins, Chaperones, Biosynthesis of Proteins, Post-Translational Modifications of Proteins
Course Precondition
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Knows the importance of protein synthesis for the organism. |
| LO02 | Knows the structural three-dimensional structures of proteins resulting from protein synthesis |
| LO03 | Know the clinical importance of proteins and functions. |
| LO04 | Know the biosynthesis of proteins. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | - | Based on the undergraduate level qualifications, develops and deepens the knowledge in the same or different field at the level of expertise and analyzes and interprets them using statistical methods. | |
| PLO02 | - | Gains the ability to develop and deepen the knowledge in the field of biotechnology | |
| PLO03 | - | Identifies the interdisciplinary interaction of the field | |
| PLO04 | - | Interpret the knowledge gained in the field by integrating the information from different disciplines and creates new information | |
| PLO05 | - | Solve problems encountered in the field by using research methods. | |
| PLO06 | - | Develops new strategic approaches for solving complex problems that are encountered in applications related to the field. | |
| PLO07 | - | Solve problems encountered in the field by using research methods. | |
| PLO08 | - | It supervises and teaches the social, scientific, cultural and ethical values during the collection, interpretation, implementation and announcement of the data related to the field. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | General properties of protein structure | Lecture, question and answer, discussion | |
| 2 | Basic structures of amino acids, amino acid groups | Lecture, question and answer, discussion | |
| 3 | Peptide bonds, Polypeptides | Lecture, question and answer, discussion | |
| 4 | Purification and characterization of proteins | Lecture, question and answer, discussion | |
| 5 | Homogenization, fractionation, precipitation | Lecture, question and answer, discussion | |
| 6 | Chromatographic Separation | Lecture, question and answer, discussion | |
| 7 | Electrophoresis | Lecture, question and answer, discussion | |
| 8 | Mid-Term Exam | ||
| 9 | Structural Analysis of Proteins | Lecture, question and answer, discussion | |
| 10 | Determination of Disulfide Bridges | Lecture, question and answer, discussion | |
| 11 | Use of Mass Spectrometry in Structural Analysis | Lecture, question and answer, discussion | |
| 12 | Detection of Protein Structure by X-Ray Diffraction and NMR Spectroscopy | Lecture, question and answer, discussion | |
| 13 | Biological Functions of Proteins Enzymes | Lecture, question and answer, discussion | |
| 14 | Hemoglobin, Myoglobin, Immunoproteins, Chaperones | Lecture, question and answer, discussion | |
| 15 | Biosynthesis of proteins | Lecture, question and answer, discussion | |
| 16 | Term Exams | ||
| 17 | Term Exams |