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Information
| Unit | FACULTY OF SCIENCE AND LETTERS |
| BIOLOGY PR. | |
| Code | BL494 |
| Name | Toxicology |
| Term | 2020-2021 Academic Year |
| Semester | 8. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Label | E Elective |
| Mode of study | Uzaktan Öğretim |
| Catalog Information Coordinator | Prof. Dr. ELİF ORUÇ |
| Course Instructor |
Prof. Dr. ELİF ORUÇ
(Bahar)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
The aim of this course is to provıde knowledge and understanding about the principles of toxicology, xenobiotic metabolism. Also it will be discussed on cell damage together with biochemical and molecular toxicity mechanisms of xenobiotics.
Course Content
This course includes; Principles of toxicology, toxic effect mechanisms of xenobiotics, cell damage and protective mechanisms
Course Precondition
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explains the general principles of toxicology, absorption, distribution, metabolism, side of action and excretion of toxic substance |
| LO02 | Explains toxic effect mechanisms of xenobiotics |
| LO03 | Describes the cell damage and protective mechanisms |
| LO04 | classifies the detail information about hepatotoxicity |
| LO05 | clasifies detail information about neurotoxicity |
| LO06 | Explains hydroxylation reactions |
| LO07 | Explains Phase II Conjugation reactions |
| LO08 | Explains kidney toxicity |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | - | Explain the basic concepts and principles in biology | 5 |
| PLO02 | - | The knowledge gained in the field of biology combine with information from other sciences. | 5 |
| PLO03 | - | Identifies problems in the field of biology and apply methods for their solution | 5 |
| PLO04 | - | Describes the method of producing scientific knowledge in the field of biology | 5 |
| PLO05 | - | They will receive information on the biology area, in order to classify it uses and purposes. | 5 |
| PLO06 | - | They use advanced theoretical and practical knowledge that obtain in biology field. | 5 |
| PLO07 | - | They are Field-related issues can inform the relevant persons and institutions, They share ideas and problems relating to suggestions as the written, oral and Visual to expert or transfer to non-experts. | 5 |
| PLO08 | - | They can take responsibility as individuals and team members to solve unpredictable problems encountered in applications related to the field. | 5 |
| PLO09 | - | they can take an active role as a member of the execution team the planning of projects related to the field. | 5 |
| PLO10 | - | They know that life-long learning process and act accordingly. | 5 |
| PLO11 | - | They will increase the knowledge and experience outside major issues with specific elective courses in different fields of biology. | 5 |
| PLO12 | - | They speak English enough to communicate with colleagues to understand the basic concepts of biology. | 1 |
| PLO13 | - | They both with colleagues, as well as areas with non-person establishes ethical uses of information and communication technology. In addition to professional development, in line with the interests and abilities of scientific, social, constantly improves itself by identifying learning needs in cultural and artistic fields. | 5 |
| PLO14 | - | They assesses developments in biology versatile using scientific methods and techniques | 5 |
| PLO15 | - | They know the importance of personal development and enforces the need. | 5 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to toxicology | Review of the relevant pages from sources | |
| 2 | Absorption, distribution, metabolism, side of action and excretion | Review of the relevant pages from sources | |
| 3 | Phase I metabolism and pharmacogenetic | Review of the relevant pages from sources | |
| 4 | Conjugation and elimination of toxic substances | Review of the relevant pages from sources | |
| 5 | Physiological factors affecting xenobiotic metabolism | Review of the relevant pages from sources | |
| 6 | Adaptation | Review of the relevant pages from sources | |
| 7 | Cell injury and cellular protection mechanism | Review of the relevant pages from sources | |
| 8 | Mid-Term Exam | Review of the relevant pages from sources | |
| 9 | Reactive metabolites and toxicity | Review of the relevant pages from sources | |
| 10 | Central nervous system and toxicity | Review of the relevant pages from sources | |
| 11 | Neurodegenerative disease neurotoxicity mechanisms | Review of the relevant pages from sources | |
| 12 | Hepatotoxicity | Review of the relevant pages from sources | |
| 13 | Nutritional Factors | Review of the relevant pages from sources | |
| 14 | Toxic effects of global warming | Review of the relevant pages from sources | |
| 15 | Molecular techniques in toxicology | Review of the relevant pages from sources | |
| 16 | Term Exams | ||
| 17 | Term Exams |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 24 | 24 |
| Total Workload (Hour) | 88 | ||
| Total Workload / 25 (h) | 3,52 | ||
| ECTS | 4 ECTS | ||