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Information
| Unit | FACULTY OF PHARMACY |
| PHARMACY PR. | |
| Code | ECF413 |
| Name | Pharmaceutical Toxicology |
| Term | 2020-2021 Academic Year |
| Semester | 7. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Label | C Compulsory |
| Mode of study | Uzaktan Öğretim |
| Catalog Information Coordinator | Doç. Dr. Göksun DEMİREL |
| Course Instructor |
Doç. Dr. Göksun DEMİREL
(Güz)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
It is aimed to inform the students about basic toxicology, specific toxicology issues, target organ toxicity, xenobiotic toxicity and poisoning.
Course Content
History of toxicology and general concepts; toxicity tests; toxicokinetics; mechanisms of toxic effects; factors affecting toxicity; classification of toxic effects; genotoxic effects and factors; teratogenicity and teratogenic compounds; carcinogenicity and carcinogenic compounds; allergic reactions and immunotoxic effect; genetic polymorphism; toxicological evaluation of drug-drug, drug-disease, drug-nutrient interactions; acute poisoning treatment.
Course Precondition
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Has knowledge about basic concepts of toxicology. |
| LO02 | Has knowledge about toxicokinetic and toxic effects mechanisms. |
| LO03 | Has knowledge about special toxic effects and toxic results of genetic polymorphism. |
| LO04 | Drug-drug, drug-nutrient interactions have information about the evaluation of toxicological aspects. |
| LO05 | Have knowledge about the general principles of acute poisoning treatment. |
| LO06 | Equipped with target organ toxicity. |
| LO07 | o have knowledge about drug and other xenobiotics and poisoning and treatment approaches. |
| LO08 | Has knowledge about the toxic effects of biotechnological products and nanotoxicology. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | - | Have sufficient knowledge in pharmaceutical field and develop the knowledge gained. | 4 |
| PLO02 | - | Applies the profession in accordance with the existing laws and regulations,gains awareness of professional and ethical responsibility. | 1 |
| PLO03 | - | It serves the society as a pharmacist who is loyal to Atatürk's principles and reforms, equipped with Universal Knowledge, who uses Turkish correctly and knows at least one foreign language. | 1 |
| PLO04 | - | Communicates effectively both orally and in writing. | 1 |
| PLO05 | - | External appearance, attitude, attitude and behavior, with professional identity, role model and society becomes an example to colleagues. | 2 |
| PLO06 | - | Provides consultancy services to patients, community and health care personnel with a wide range of information on the drug,evaluates advanced knowledge and skills with a critical approach. | 2 |
| PLO07 | - | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 1 |
| PLO08 | - | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | 0 |
| PLO09 | - | Interprets information about current health and treatment problems. Plays an active role in community health. | 1 |
| PLO10 | - | Pharmacy integrates and develops professional knowledge with information from different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 2 |
| PLO11 | - | Students will be able to use the concepts and applications of basic sciences and basic medical sciences effectively in the field of Medicine and pharmacy and have the experience of working with these health sciences. | 2 |
| PLO12 | - | Acquires basic information about diseases, adopts and applies rational drug use on all drugs that affect systems. | 2 |
| PLO13 | - | By learning the basics of Clinical Pharmacy,will have the knowledge and skills to help provide drug/patient oriented pharmacy applications and individualized Pharmaceutical Care. | 3 |
| PLO14 | - | It plays a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to Toxicology: Definitions and Basic Concepts | Textbooks and current literature | |
| 2 | Toxicity Mechanisms and Factors Affecting Toxicity | Textbooks and current literature | |
| 3 | Toxicokinetic I: Absorption, Distribution and Elimination of Xenobiotics | Textbooks and current literature | |
| 4 | Toxicokinetic II: Biotransformation of xenobiotics | Textbooks and current literature | |
| 5 | Toksisite Testleri ve Risk değerlendirmesi | Textbooks and current literature | |
| 6 | Acute Poisoning Therapy and Antidote | Textbooks and current literature | |
| 7 | Specific Toxic Effects I: Genotoxicity, Mutagenicity, Carcinogenicity | Textbooks and current literature | |
| 8 | Mid-Term Exam | Exam | |
| 9 | Specific Toxic Effects II: Reproductive and Developmental Toxicity | Textbooks and current literature | |
| 10 | Other Risks of Drug Use in Pregnancy and Teratogenicity | Textbooks and current literature | |
| 11 | ntroduction to Immunotoxicology and Allergic Reactions | Textbooks and current literature | |
| 12 | Genetic Polymorphism-Related Toxic Effects | Textbooks and current literature | |
| 13 | Toxicological Evaluation of Biotechnological Products, Possible Toxic Effects of Vaccine Components | Textbooks and current literature | |
| 14 | Toxic Effects of Nanomaterials | Textbooks and current literature | |
| 15 | Environmental Toxicology and Disaster Toxicology | Textbooks and current literature | |
| 16 | Term Exams | Final Exam | |
| 17 | Term Exams | Final Exam |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Homework | 100 | 40 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 78 | ||
| Total Workload / 25 (h) | 3,12 | ||
| ECTS | 3 ECTS | ||