TÜRKÇE
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Information
| Unit | FACULTY OF PHARMACY |
| PHARMACY PR. | |
| Code | ECS411 |
| Name | Drug Development and Active Substance Synthesis Methods |
| Term | 2020-2021 Academic Year |
| Semester | 7. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 2 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Label | E Elective |
| Mode of study | Uzaktan Öğretim |
| Catalog Information Coordinator | Prof. Dr. Hacı Ali DÖNDAŞ |
| Course Instructor |
Prof. Dr. Hacı Ali DÖNDAŞ
(Güz)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
The scope of this course is to teach the drug development and drug active substance synthesis strategies
Course Content
Drug Development, Molecular Modeling in Drug Design, Computer Aided Drug Design (CADDs), In the development of new drug molecules; Combinatorial chemistry, High throughput screening (HTS) and Quantitative structure activity relationship (QSAR), Organic synthesis strategies, synthetic methods for drug active substance, Determination of the lead compound, Synthesis of analogues and Chemical modification, Semi synthetic strategies, biosynthesis and Full synthesis
Course Precondition
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | To define the general concepts related to molecular modeling in drug design |
| LO02 | To explain the importance of molecular modeling in drug design |
| LO03 | To know the methods used in the development of new molecules |
| LO04 | To describe the information about organic synthesis strategies |
| LO05 | To know drug the synthetic methods about drug active substance |
| LO06 | To describe the importance of molecular modeling in drug desig |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | - | Have sufficient knowledge in pharmaceutical field and develop the knowledge gained. | |
| PLO02 | - | Applies the profession in accordance with the existing laws and regulations,gains awareness of professional and ethical responsibility. | |
| PLO03 | - | It serves the society as a pharmacist who is loyal to Atatürk's principles and reforms, equipped with Universal Knowledge, who uses Turkish correctly and knows at least one foreign language. | |
| PLO04 | - | Communicates effectively both orally and in writing. | |
| PLO05 | - | External appearance, attitude, attitude and behavior, with professional identity, role model and society becomes an example to colleagues. | |
| PLO06 | - | Provides consultancy services to patients, community and health care personnel with a wide range of information on the drug,evaluates advanced knowledge and skills with a critical approach. | |
| PLO07 | - | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | |
| PLO08 | - | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | |
| PLO09 | - | Interprets information about current health and treatment problems. Plays an active role in community health. | |
| PLO10 | - | Pharmacy integrates and develops professional knowledge with information from different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | |
| PLO11 | - | Students will be able to use the concepts and applications of basic sciences and basic medical sciences effectively in the field of Medicine and pharmacy and have the experience of working with these health sciences. | |
| PLO12 | - | Acquires basic information about diseases, adopts and applies rational drug use on all drugs that affect systems. | |
| PLO13 | - | By learning the basics of Clinical Pharmacy,will have the knowledge and skills to help provide drug/patient oriented pharmacy applications and individualized Pharmaceutical Care. | |
| PLO14 | - | It plays a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Drug Development | Books and scientific databases | |
| 2 | Molecular Modeling in Drug Design | Books and scientific databases | |
| 3 | Computer Aided Drug Design (CADDs) | Books and scientific databases | |
| 4 | Combinatorial chemistry | Books and scientific databases | |
| 5 | High-throughput screening (HTS) | Books and scientific databases | |
| 6 | Quantitative structure activity relationship (QSAR) | Books and scientific databases | |
| 7 | Organic synthesis strategies | Books and scientific databases | |
| 8 | Mid-Term Exam | ||
| 9 | Synthetic methods for drug active substance | Books and scientific databases | |
| 10 | Determination of the lead compound | Books and scientific databases | |
| 11 | Synthesis of analogues and Chemical modification | Books and scientific databases | |
| 12 | Semi-synthetic strategies | Books and scientific databases | |
| 13 | biosynthesis | Books and scientific databases | |
| 14 | Full synthesis | Books and scientific databases | |
| 15 | Full synthesis | Books and scientific databases | |
| 16 | Term Exams | ||
| 17 | Term Exams |