TÜRKÇE
ENGLISH
Information
| Unit | FACULTY OF PHARMACY |
| PHARMACY PR. | |
| Code | ECS523 |
| Name | Microbial Antibiotic Synthesis |
| Term | 2021-2022 Academic Year |
| Semester | 9. Semester |
| Duration (T+A) | 1-1 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 1.5 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Label | E Elective |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi ABDURRAHMAN AYGÜL |
| Course Instructor |
Dr. Öğr. Üyesi ABDURRAHMAN AYGÜL
(Güz)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
To inform students theoretically about obtaining of antibiotics from bacterial/fungal microorganisms with traditional methods and to gain basic application skills on the subject.
Course Content
It covers the isolation of bacterial / fungal microorganisms from environmental sources such as soil, surface water, wild plants and naturally antibiotic extraction processes from them.
Course Precondition
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Exemplifies microorganisms that naturally produce antibiotics |
| LO02 | Isolate Streptomyces griseus from the environmen using agar plate |
| LO03 | Isolate Penicillium chrysogenum from the environmen using agar plate |
| LO04 | Counts the parts of simple bioreactors |
| LO05 | Explain the fermentation concept with examples |
| LO06 | Counts the process of preparing a bioreactor in sterile steps for antibiotic synthesis. |
| LO07 | Explain penicillin isolation from the fermentation environment in the bioreactor. |
| LO08 | Explain the isolation of streptomycin from the fermentation environment in the bioreactor. |
| LO09 | Detects the sensitivity of antibiotics isolated using disc diffusion test |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | - | Have sufficient knowledge in pharmaceutical field and develop the knowledge gained. | 1 |
| PLO02 | - | Applies the profession in accordance with the existing laws and regulations,gains awareness of professional and ethical responsibility. | 0 |
| PLO03 | - | It serves the society as a pharmacist who is loyal to Atatürk's principles and reforms, equipped with Universal Knowledge, who uses Turkish correctly and knows at least one foreign language. | 0 |
| PLO04 | - | Communicates effectively both orally and in writing. | 0 |
| PLO05 | - | External appearance, attitude, attitude and behavior, with professional identity, role model and society becomes an example to colleagues. | 0 |
| PLO06 | - | Provides consultancy services to patients, community and health care personnel with a wide range of information on the drug,evaluates advanced knowledge and skills with a critical approach. | 0 |
| PLO07 | - | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 0 |
| PLO08 | - | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | 0 |
| PLO09 | - | Interprets information about current health and treatment problems. Plays an active role in community health. | 0 |
| PLO10 | - | Pharmacy integrates and develops professional knowledge with information from different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 0 |
| PLO11 | - | Students will be able to use the concepts and applications of basic sciences and basic medical sciences effectively in the field of Medicine and pharmacy and have the experience of working with these health sciences. | 2 |
| PLO12 | - | Acquires basic information about diseases, adopts and applies rational drug use on all drugs that affect systems. | 0 |
| PLO13 | - | By learning the basics of Clinical Pharmacy,will have the knowledge and skills to help provide drug/patient oriented pharmacy applications and individualized Pharmaceutical Care. | 0 |
| PLO14 | - | It plays a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 0 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | History of antibiotics | Related publications and books | |
| 2 | Bacteria - fungal joint cultures | Related publications and books | |
| 3 | Environmental microorganisms and antibiotic synthesis | Related publications and books | |
| 4 | Simple bioreactor design and installation | Related publications and books | |
| 5 | Fermentation | Related publications and books | |
| 6 | Isolation | Related publications and books | |
| 7 | Quantification | Related publications and books | |
| 8 | Mid-Term Exam | ||
| 9 | Streptomyces griseus isolation for obtaining streptomycin | Related publications and books | |
| 10 | Obtaining streptomycin 1 | Related publications and books | |
| 11 | Obtaining streptomycin 2 | Related publications and books | |
| 12 | Penicillium chrysogenum isolation for obtaining penicillin | Related publications and books | |
| 13 | Obtaining penicillin 1 | Related publications and books | |
| 14 | Obtaining penicillin 2 | Related publications and books | |
| 15 | Activity determinations of synthesized antibiotics | Related publications and books | |
| 16 | Term Exams | ||
| 17 | Term Exams |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Midterm Exam | 100 | 40 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 2 | 2 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 80 | ||
| Total Workload / 25 (h) | 3,20 | ||
| ECTS | 3 ECTS | ||