TÜRKÇE
ENGLISH
Information
| Unit | FACULTY OF PHARMACY |
| PHARMACY PR. | |
| Code | ECS318 |
| Name | Standardization and Quality Control Methods in Phytotherapeuticals |
| Term | 2021-2022 Academic Year |
| Semester | 6. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 2 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Label | E Elective |
| Mode of study | Uzaktan Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi TUBA ŞERBETÇİ |
| Course Instructor |
Dr. Öğr. Üyesi Seçil KARAHÜSEYİN
(Bahar)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
It is aimed to emphasize the necessity and importance of standardization process in herbal products and to give information about chromatographic analysis.
Course Content
In order to get the desired benefit from the plants, it is necessary to process the right plant correctly and to prepare preparations / products with high efficiency, reliability and quality.
Course Precondition
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explain the defiinition of quality for herbal preparations. |
| LO02 | Give information about fferent formulations of phytotherapeuticals |
| LO03 | Classify herbal medicines and give examples. |
| LO04 | Explain standardization in phytotherapeuticals |
| LO05 | Explain phytochemical evaluation methods for standardisation |
| LO06 | Array the necessity of standardization |
| LO07 | Explain the importance of good agricultural practice for phytotherapeuticals |
| LO08 | Give information about the chromatographic techniques |
| LO09 | Explain the quality-control methods present in Pharmacopeia |
| LO10 | Give information about herbal monographs |
| LO11 | Explain ash values quantification methods |
| LO12 | Explain lost in drying methods |
| LO13 | Explain the importance of heavy metals analyses |
| LO14 | Explain the importance of microscopical examination |
| LO15 | Explain phytochemical analyses and bioactive component quantification methods |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 3 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 3 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 2 |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to standardisaiton of phytotherapeuticals | Textbooks, current literature on the subject | |
| 2 | Adulteration/substitution, identity and purity | Textbooks, current literature on the subject | |
| 3 | Macro and microscopic examination for identification of right variety and search of adulterants. | Textbooks, current literature on the subject | |
| 4 | Foreign organic matter investigation | Textbooks, current literature on the subject | |
| 5 | Ash values, criteria to judge the identity and purity of crude drug | Textbooks, current literature on the subject | |
| 6 | Moisture content | Textbooks, current literature on the subject | |
| 7 | Extractive values and the effect of different methods to extrative values | Textbooks, current literature on the subject | |
| 8 | Mid-Term Exam | exams | |
| 9 | Qualitative chemical evaluation of crude drug with respect to phytochemical constituent | Textbooks, current literature on the subject | |
| 10 | Chromatographic examination: Include identification of crude drug based on the use of major chemical constituents as markers | Textbooks, current literature on the subject | |
| 11 | Quantitative chemical evaluation: To estimate the amount of the major classes of constituents. | Textbooks, current literature on the subject | |
| 12 | The importance of analytical methods for the quality-control management of herbal drugs | Textbooks, current literature on the subject | |
| 13 | Other critical factors affecting the quality control of herbal drugs | Textbooks, current literature on the subject | |
| 14 | Microbial contaminants and aflatoxins | Textbooks, current literature on the subject | |
| 15 | Good agricultural/Manufacturing practices | Textbooks, current literature on the subject | |
| 16 | Term Exams | exams | |
| 17 | Term Exams | exams |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Homework | 100 | 40 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 1 | 14 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 4 | 4 |
| Final Exam | 1 | 8 | 8 |
| Total Workload (Hour) | 54 | ||
| Total Workload / 25 (h) | 2,16 | ||
| ECTS | 2 ECTS | ||