TÜRKÇE
ENGLISH
Information
| Code | BL448 |
| Name | Antibiotics and Their Influence Mechanisms |
| Term | 2022-2023 Academic Year |
| Semester | 8. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. HATİCE GÜVENMEZ |
| Course Instructor |
Prof. Dr. HATİCE GÜVENMEZ
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Teaching the Influence of chemical and biological antimicrobial agents on micro-organisms, microorganisms have developed mechanisms of resistance to these agents behaviors
Course Content
Chemical antimicrobial agents, control of microbial growth Antibiotics targets Synthetic antimicrobial drugs Natural antimicrobial drugs: Antibiotics The antibiotics of inhibiting of cell wall synthesis: Penicillins, cephalosporins, bacitracins, carbapenem, monobactam, vancomycine The antibiotics of inhibiting of protein synthesis: Macrolids, aminoglycozides, tetracyclins, lincosamide DNA-gyrase inhibitors; quinolons Lipid biosynthesis inhibitors, antimicrobial agents on folic acid metabolism antimicrobial agents on sytoplasmic membrane structure and function: polymyxines, daptomycine antiviral agents antifungal agents antiparasiter agents
Course Precondition
None
Resources
Brock, Biology of Microorganisms, 14th Edition
Notes
Current Literatures
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | explain the effects of antimicrobial agents and resistance mechanisms of microorganisms |
| LO02 | Understands the organism pathways in the use of an antimicrobial agent in vivo |
| LO03 | Explain the application sites and pathways of antimicrobial agents |
| LO04 | Understands ther targets of antibiotics |
| LO05 | Understands the synthetic antimicrobial drugs |
| LO06 | Understands the folic acid metabolism effective antimicrobial agents |
| LO07 | Explain the antiviral agents |
| LO08 | Explain the Protein synthesis inhibitors |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explain the basic concepts and principles in biology | |
| PLO02 | Bilgi - Kuramsal, Olgusal | The knowledge gained in the field of biology combine with information from other sciences. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Identifies problems in the field of biology and apply methods for their solution | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Describes the method of producing scientific knowledge in the field of biology | 4 |
| PLO05 | Bilgi - Kuramsal, Olgusal | They will receive information on the biology area, in order to classify it uses and purposes. | 4 |
| PLO06 | Bilgi - Kuramsal, Olgusal | They use advanced theoretical and practical knowledge that obtain in biology field. | 4 |
| PLO07 | Bilgi - Kuramsal, Olgusal | They are Field-related issues can inform the relevant persons and institutions, They share ideas and problems relating to suggestions as the written, oral and Visual to expert or transfer to non-experts. | 4 |
| PLO08 | Bilgi - Kuramsal, Olgusal | They can take responsibility as individuals and team members to solve unpredictable problems encountered in applications related to the field. | 3 |
| PLO09 | Bilgi - Kuramsal, Olgusal | they can take an active role as a member of the execution team the planning of projects related to the field. | 3 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | They know that life-long learning process and act accordingly. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They will increase the knowledge and experience outside major issues with specific elective courses in different fields of biology. | 5 |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They speak English enough to communicate with colleagues to understand the basic concepts of biology. | 2 |
| PLO13 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | They both with colleagues, as well as areas with non-person establishes ethical uses of information and communication technology. In addition to professional development, in line with the interests and abilities of scientific, social, constantly improves itself by identifying learning needs in cultural and artistic fields. | 3 |
| PLO14 | Yetkinlikler - Öğrenme Yetkinliği | They assesses developments in biology versatile using scientific methods and techniques | |
| PLO15 | Yetkinlikler - Öğrenme Yetkinliği | They know the importance of personal development and enforces the need. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Chemical antimicrobial agents, the control of microbial growth. | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 2 | The pathway of using in vivo in organism of an antimicrobial agent | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 3 | Places and ways of application of antimicrobial agents. | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 4 | Targets of antibiotics | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 5 | Synthetic antimicrobial drugs | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 6 | Natural antimicrobial drugs: Antibiotics | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 7 | Cell wal synthesis inhibitors: Penicilline, cephalosporins, bacitracins, carbapenems, monobactam, vancomycine | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 8 | Mid-Term Exam | An overview | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Protein synthesis inhibitors: macrolida, aminoglycoside, tetracycline, lincozamids | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 10 | DNA-gyrase inhibitors: Quinolons | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 11 | Lipid biosynthesis inhibitors | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 12 | Folic acid metabolism effective antimicrobial agents | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 13 | Antiviral agents | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 14 | Antifungal agents | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Tartışma |
| 15 | Antiparasiter agents | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | An overview | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | An overview | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 4 | 4 | 16 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 12 | 12 |
| Total Workload (Hour) | 92 | ||
| Total Workload / 25 (h) | 3,68 | ||
| ECTS | 4 ECTS | ||