TÜRKÇE
ENGLISH
Information
| Code | ECF422 |
| Name | Pharmaceutical Biotechnology |
| Term | 2022-2023 Academic Year |
| Semester | 8. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 2 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Label | C Compulsory |
| Mode of study | Uzaktan Öğretim |
| Catalog Information Coordinator | Doç. Dr. UMAY MERVE GÜVEN |
| Course Instructor |
Doç. Dr. UMAY MERVE GÜVEN
(A Group)
(Ins. in Charge)
Gülay BÜYÜKKÖROĞLU (A Group) (Asst. Ins.) Behiye ŞENEL (A Group) (Asst. Ins.) Dr. Öğr. Üyesi ESRA DEMİRTÜRK (A Group) (Asst. Ins.) |
Course Goal / Objective
The aim of this course is to explain the roles, duties and responsibilities of the pharmacist who has knowledge about pharmaceuticals, biological medicinal products and combination products within the scope of pharmaceutical biotechnology, their life cycles in health system including clinical research of these drugs / products.
Course Content
biological medicinal products, biosimilar drugs, advanced therapy medicinal products, stem cell-derived drugs, personalized (individual) drugs, production technologies, quality assurance
Course Precondition
None.
Resources
None.
Notes
None.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explains pharmaceutical biotechnology and research subjects. |
| LO02 | List the uses of recombinant DNA technology. |
| LO03 | Explain gene cloning steps. |
| LO04 | Classifies therapeutic proteins according to their biological function. |
| LO05 | Discusses pharmaceutical forms in a comparative manner. |
| LO06 | Discuss the appropriateness of the routes of administration of pharmaceutical forms depending on the protein properties. |
| LO07 | List the finished product analyzes of the recombinant Therapeutic protein. |
| LO08 | Discuss the finished product stability studies and the methods used. |
| LO09 | Discuss the transfer of the amplified DNA to the vector. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 5 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 4 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | 2 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 2 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 4 |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | 3 |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | 2 |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to molecular biotechnology and pharmaceutical biotechnology | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 2 | Hybridoma technology, monoclonal antibodies, properties and analysis | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Physicochemical properties, stability and analysis methods of peptides and proteins | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Vaccines (recombinant and DNA vaccines) vaccine adjuvants, properties and analyzes | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Preformulation and formulation in recombinant protein drugs | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Preformulation, formulation, pharmacopeia analysis and quality controls in recombinant protein drugs | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Biosimilar drugs | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Advanced treatments, advanced treatment medical products, combined advanced treatment medical products | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Stem cell technologies, stem cell-derived medical products | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Gene technologies, gene transfer methods | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | pharmacogenomics | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | clinical research and regenerative medical studies | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | analyzes in recombinant proteins | Reading on the subject | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | pharmacopoeia analysis and quality controls | Reading on the subject | Öğretim Yöntemleri: Anlatım, Tartışma |
| 16 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Subject repetition | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 1 | 14 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 4 | 4 |
| Final Exam | 1 | 8 | 8 |
| Total Workload (Hour) | 54 | ||
| Total Workload / 25 (h) | 2,16 | ||
| ECTS | 2 ECTS | ||