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Information
| Code | VET233 |
| Name | Genetics and Molecular Biology |
| Term | 2022-2023 Academic Year |
| Semester | 3. Semester |
| Duration (T+A) | 1-1 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 1 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. TÜLİN GÜVEN GÖKMEN |
| Course Instructor |
Doç. Dr. TÜLİN GÜVEN GÖKMEN
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
It aims to learn how the differences between the living things of the students arise from what they are, the genotypic effect of these differences, how the genetic information is transferred from one generation to the next, the definition and structure of genes, intergenerational interactions, genotype x environment interactions, hereditary diseases, hereditary diseases, mutations, and general principles in molecular biology, DNA and RNA constructs and functions, transcription and translation mechanisms, cloning with recombinant DNA technologies and gene expression and molecular biology methods.
Course Content
The source of the differences among living things, genotype, phenotype, transfer of genetic information from front to back, DNA and RNA structures and functions, polymerase chain reaction, transcription and translation processes, cloning with recombinant DNA technologies and gene expressions, interactions between genes, genotype x environment interactions, hereditary diseases, hereditary diseases, mutation, population genetics
Course Precondition
There is no prerequisite.
Resources
Lecture Notes
Notes
Veterinary Genetic: Prof. Dr. Bilal Akyüz , Prof. Dr. Akın Yakan et al.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Defines the basic concepts of genetics. |
| LO02 | Explains the structures of DNA, RNA molecules. |
| LO03 | Explains the processes of replication, transcription and translation. |
| LO04 | Learns molecular techniques that can be applied in areas such as infectious diseases, hereditary diseases and food analysis in veterinary medicine. |
| LO05 | Knows the contribution of genetics in the formation of diseases and that genetic defects may be responsible for the etiology of the disease. |
| LO06 | Learns how to use genetic structure and which tests to choose in race determination, parenting tests and similar areas. |
| LO07 | Comprehends molecular genetic methods such as hybridoma technology used in veterinary medicine, cloning, stem cells, transgenic animals, embryo transfer, poly and monoclonal antibody production, DNA damage detection. |
| LO08 | Explains the population genetics and hardy weinberg hypothesis |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Learns animal species and breeds, recognizes structural, functional and behavioral characteristics (anatomical, histological, physiological, biochemical, etc.). | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | It determines the care and nutrition alternatives for healthy aquaculture and prepares feeding programs suitable for the purpose in accordance with the cultivation patterns and expected yield characteristics of different animal species. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Determine the diagnosis and treatment protocols of diseases. | 4 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Learns basic information about chemical and biological substances to be used for prevention and treatment of diseases and their production technologies. | 4 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Evaluates the efficiency of animal breeds. Learns the level of animal breeding. Able to manage an animal selection, hybridization and artificial insemination program. | 5 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Makes the most appropriate management planning for livestock enterprises. | 3 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Has knowledge about animal rights and animal owner rights. | |
| PLO08 | Bilgi - Kuramsal, Olgusal | Has sufficient technology knowledge about hygienic production, production, presentation and sales of animal foods produced for human consumption and / or products of animal products. | 3 |
| PLO09 | Bilgi - Kuramsal, Olgusal | Learns national and international laws and regulations related to veterinary medicine. | 3 |
| PLO10 | Bilgi - Kuramsal, Olgusal | A veterinary practitioner manages animal husbandry enterprises, animal husbandry scientific research centers and animal food production enterprises by utilizing the knowledge gained in the veterinary medicine education and by observing the professional principles. | 2 |
| PLO11 | Bilgi - Kuramsal, Olgusal | Recognizes all kinds of diseases that are possible in animals, uses diagnostic methods for this purpose, receives diagnostic materials if necessary and sends them to authorized laboratories and treats the diseases diagnosed by using all methods of medicine (such as interpretation of diagnostic methods results, drug or operative applications). It takes necessary security measures including biosecurity for the control of infectious diseases. | 4 |
| PLO12 | Bilgi - Kuramsal, Olgusal | Prepares and uses the theoretical maintenance-feed protocols. Makes necessary applications for economic aquaculture by considering the characteristics at the business and regional level. | |
| PLO13 | Bilgi - Kuramsal, Olgusal | Inspects the production of animal foods and products of animal origin which produced for human consumption and performs health control of the final foodstuffs. | 3 |
| PLO14 | Bilgi - Kuramsal, Olgusal | Being aware of the duties and responsibilities to have the consciousness of exercising the profession. Takes responsibility in individual and group work, fulfills the task in line with the skills. | |
| PLO15 | Bilgi - Kuramsal, Olgusal | In cooperation with other experts in problems outside the field of expertise, the team contributes to the solution as a member. Also trying to find solutions to common problems at the regional or national level as well as communication with other professionals. | 2 |
| PLO16 | Beceriler - Bilişsel, Uygulamalı | Comprehends the methods of producing and using scientific knowledge. Evaluates the knowledge and skills gained in a critical way, identifies the new information and information sources that should be acquired in relation to the field and participates in the activities that will meet the learning needs. | 4 |
| PLO17 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes tasks related to the field in professional councils and organizations. Based on his professional skills and competences, he plans and realizes social projects with the awareness of society. Provides information on the problems of public and animal health related to the definition of the problem and the solution proposals and organizes events. | |
| PLO18 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | He / she can continue his / her professional development and use at least one foreign language (at least European Language Portfolio B1 general level) to establish social relations. At least at the Advanced Level of European Computer Driving License, it uses computer software and other technological tools that may be needed at professional level and social relations level. He follows the world agenda closely and is sensitive to events. | 3 |
| PLO19 | Yetkinlikler - Öğrenme Yetkinliği | Be aware of the needs of the country and the region, and if necessary, guide them in their practice. It defines the subject of human, animal and animal owner rights and considers animal welfare in all its practices. They have the ethical values that are required by the profession, and defend these values when necessary. Have the competence to practice and defense, dominate the concepts of occupational safety in terms of work place and the personnel working with it. It is aware of the environmental health rules and makes practices to protect nature. The environment is sensitive to veterinary public health and zoonoses. | 3 |
| PLO20 | Yetkinlikler - Öğrenme Yetkinliği | Conceptualize the facts and events related to veterinary services; examine scientific techniques and methods, interpret the results; constructs analysis or methods for problems; provides solutions and / or treatment alternatives according to the data obtained. Follows the legislation that is updated on veterinary services and uses them when necessary. | 2 |
| PLO21 | Bilgi - Kuramsal, Olgusal | Evaluate the physiological and physiopathological conditions of animals conceptually and factually. | 4 |
| PLO22 | Yetkinlikler - Alana Özgü Yetkinlik | Evaluates the laboratory results (hematological, biochemical, EKG, EEG, EMG, etc.) of animal diseases and applies correct diagnosis, diagnosis and treatment methods based on the data obtained. | 5 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Why genetic and molecular biology for veterinarians | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Structural properties of genetic material, structure of DNA and RNA, organization of DNA and genome | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | DNA replication, RNA transcription | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Control of gene expression in bacteria and mammalian cells, translation of mRNA into proteins, post-translational modifications | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Character, phenotype, genotype, environment, environment x genotype interaction, variyations | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Genetic variations and inheritance (dominant and ressesive inheritance, intermedia inheritance), independence of genes and gametes, test combinations (mono hybridism, dihibridus mutant, trihibridus mutant, poly hybridus mutant)formulas that can be useful in integrations | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Genetics and genetic code (structural genes, operator genes, regulatory genes, role of cytoplasm in heredity), genetics (cell morphology, cytoplasm, nucleus, chromatin), chromosomes (chromosomal morphology, chromosomal types, karyotypes, fine structure of chromosomes, giant chromosomes) cell protein synthesis) | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Exam preparing | Ölçme Yöntemleri: Sözlü Sınav |
| 9 | Genetic differences in cell division and division of genetic importance, crossing over | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Genetic associations (cryptomeria, epistasis, involvement of a pair of two genes in the formation of a character, pleitropi, polymeri) | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Lethal genes, methods of combating lethal genes, sex-linked inheritance | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Immunogenetics (blood groups in domestic animals, techniques used in blood group studies, parenting tests, relation of blood groups to yields) | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Recombinations (conjugation, transduction, transformation) | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Mutations (deficiency, deletion, inversion, duplication, translocation, euphly, monoploidy, polyploidy, gene mutations), change of chromosome number | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Molecular genetics, Polymerase chain reaction and its importance in the diagnosis of diseases, recombinant gene technology, Hybridoma technology, recombinant gene technology, poly and monoclonal antibody production, DNA damage detection | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Population genetic | Lectures note | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 17 | Term Exams | exam preparingr | Ölçme Yöntemleri: Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 2 | 2 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 80 | ||
| Total Workload / 25 (h) | 3,20 | ||
| ECTS | 3 ECTS | ||