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Information
| Code | ABL663 |
| Name | Pharmacokinetics |
| Term | 2022-2023 Academic Year |
| Term | Spring |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. MEHMET ATA SEÇİLMİŞ |
| Course Instructor |
1 |
Course Goal / Objective
Absorption, distribution, metabolism (biotransformation) and elimination of drugs. To investigate the relationship between the concept of pharmacokinetics and the treatment and adverse effects.
Course Content
Absorption, distribution, metabolism (biotransformation) and elimination of drugs. To investigate the relationship between the concept of pharmacokinetics and the treatment and adverse effects.
Course Precondition
None
Resources
1. Basic and Clinical Pharmacology (Katzung), 2. The Pharmacologıcal Basıs of Therapeutıcs (Goodman and Gilman), 3. Akılcıl Tedavi Yönünden Tıbbi Farmakoloji, Editör: Prof. Dr. S. Oğuz Kayaalp
Notes
Internet and library databases
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Learn the clinical importance of time-concentration and concentration-effect relationships of drugs. |
| LO02 | Be familiar with the concepts related to drug absorption and distribution. |
| LO03 | İlaç eliminasyonuna ilişkin kavramlara aşina olur. |
| LO04 | Interpret the models of compartment. |
| LO05 | Learns the use of drug pharmacokinetic information in clinical applications. |
| LO06 | Learns linear regression and slope calculation. |
| LO07 | They are familiar with the methods of modeling and pharmacokinetic variables through time-concentration graphs. |
| LO08 | Learns to use pharmacokinetic information in clinical applications. |
| LO09 | Familiar with dose adjustment in renal failure. |
| LO10 | Interpret the relationship between pharmacokinetic and pharmacological response |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develops current and advanced knowledge in forensic sciences at the level of expertise. | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends the research methods related to Forensic Sciences at expertise level. | 2 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Knows the importance of ethical principles for society and person. | |
| PLO04 | Yetkinlikler - Alana Özgü Yetkinlik | Develops a new idea, method, design and/or application on forensic sciences. | 2 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Can write scientific articles related to Forensic Sciences. | |
| PLO06 | Yetkinlikler - Öğrenme Yetkinliği | Are capable of critical analysis, evaluation and synthesis of new and complex ideas. | 3 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Follows evidence-based practices and conducts research on professional practices that will constitute evidence in his field. | 2 |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Defends her/his original views when discussing the issues in her field with experts. | 2 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Can communicate with their peers, the larger scholarly community and with society in general about Forensic science area. | 2 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Contributes to the solution of social, scientific, cultural and ethical problems encountered in matters related to forensic sciences. | |
| PLO11 | Yetkinlikler - Alana Özgü Yetkinlik | Discusses current developments and her/his own work with different groups in written, oral and visual formats. | 2 |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Uses the knowledge and research methods obtained in the field in solving forensic cases and events. | 3 |
| PLO13 | Bilgi - Kuramsal, Olgusal | Knows the concept of expertise and forensic procedural approach. | |
| PLO14 | Bilgi - Kuramsal, Olgusal | Knows crime scene investigation and evidence collection procedures | |
| PLO15 | Bilgi - Kuramsal, Olgusal | Knows the concepts of crime, causes of crime and punishment. | |
| PLO16 | Bilgi - Kuramsal, Olgusal | Recognizes basic forensic medicine and forensic science applications. | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Pharmacokinetic parameters and general concepts | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 2 | The passage of drugs through biological membranes and absorption | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 3 | Drug administration routes | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 4 | Drug absorption and bioavailability | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 5 | Distribution of drugs | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 6 | Dispersion speed and distribution specific conditions, Dispersion kinetics | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 7 | Literature discussion - Review of the subject | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 8 | Mid-Term Exam | Textbooks of Pharmacology | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Drug Biotransformation - I | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 10 | Drug Biotransformation - II | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 11 | Elimination of drugs | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 12 | Kinetics of elimination | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 13 | Dose calculation for special patient groups | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 14 | Dose-concentration correlation | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 15 | Final preparation | Textbooks of Pharmacology | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Problem Çözme |
| 16 | Term Exams | Textbooks of Pharmacology | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Textbooks of Pharmacology | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 24 | 24 |
| Total Workload (Hour) | 88 | ||
| Total Workload / 25 (h) | 3,52 | ||
| ECTS | 4 ECTS | ||