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Information
| Code | FAR691 |
| Name | Vasoactive substances |
| Term | 2022-2023 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. FATMA PEYMAN ERTUĞ |
Course Goal / Objective
Dersin amacı endotel kaynaklı vazoaktif maddeleri bu maddelerin sentez ve salınımını öğretmektir.
Course Content
Synapses, junctions and receptors of sympathetic and parasympathetic systems, enteric nervous system, cholinergic and nitrergic system.
Course Precondition
None.
Resources
1.Medical Pharmacology in terms of Rational Treatment, Kayaalp SO, Hacettepe Taş Kitapçılık, Ankara, IX. edition, 2000 2. Goodman & Gilman's. Pharmacologic Basis of Therapeutics. Hardman JG, Limbird LE, IXth edition, McGraw-Hill, New York, 1996 Pharmacology, Rang, HP, Dale, MM, Ritter, JM, Churchill Livingstone, Edinburgh, V. edition, 2003 3. Pharmacology, Rang, HP, Dale, MM, Ritter, JM, Churchill Livingstone, Edinburgh, V. edition, 2003 4. Lippincott's Illustrated Reviews: Pharmacology, Mycek MJ, Harvey RA, Champe PC, 2nd edition, 1997
Notes
Internet, library databases
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Learns sympathetic and parasympathetic nervous system. |
| LO02 | Gives information about enteric nervous system, cholinergic system, nitrergic system. |
| LO03 | Knows peripheral neurotransmission, distribution of nitrergic nerves. |
| LO04 | Explain Nitric Oxide and its synthesis, modulation and inactivation of acetylcholine release. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Beceriler - Bilişsel, Uygulamalı | Interprets the mechanisms of action, side effects, toxic effects of drugs. | 5 |
| PLO02 | Beceriler - Bilişsel, Uygulamalı | Explain drug effects, drug interactions and effects on organ systems with a systematic approach. | 5 |
| PLO03 | Yetkinlikler - Alana Özgü Yetkinlik | Plans, implements and finalizes a scientific project | 2 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Knows research areas and research techniques of pharmacology | 4 |
| PLO05 | Yetkinlikler - Alana Özgü Yetkinlik | Comparatively analysis and review scientific articles in the field of pharmacology | 4 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Prepares experimental setup and solves problems for an in vitro or in vivo pharmacological research. | 3 |
| PLO07 | Yetkinlikler - Alana Özgü Yetkinlik | Writes a scientific article by using data obtained from the research project. | 3 |
| PLO08 | Yetkinlikler - Alana Özgü Yetkinlik | Evaluates the use and effects of drugs in society. | 4 |
| PLO09 | Bilgi - Kuramsal, Olgusal | Explains clinical phases of drug development | 3 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Evaluates and interprets the project data statistically. | 2 |
| PLO11 | Beceriler - Bilişsel, Uygulamalı | Contributes to public health with its awareness of rational drug use. | 1 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Sympathetic and parasympathetic nervous system | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Synapses, junctions and receptors of sympathetic and parasympathetic systems | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Enteric nervous system | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Nitrergic transmission in the enteric and autonomic nervous system | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Cholinergic system | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Modulation and inactivation of acetylcholine release | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Cholinergic receptors (cholinoreceptors) | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Reading, revision, research | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Types of cholinergic receptors, major distribution sites and distinctive features | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Peripheral neurotransmission | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Distribution of nitrergic nerves | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Nitric Oxide, synthesis | Reading, research | Öğretim Yöntemleri: Soru-Cevap, Anlatım, Tartışma |
| 13 | Nitric Oxide, effects on cardiovascular system, respiratory system, gastrointestinal system, immune system | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Nitric Oxide deficiency and treatment approaches | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Literature research, article presentation and discussion | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Reading, revision, research | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Reading, revision, research | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 24 | 24 |
| Total Workload (Hour) | 88 | ||
| Total Workload / 25 (h) | 3,52 | ||
| ECTS | 4 ECTS | ||