BİO524 Ageing Biology and Genetics

5 ECTS - 3-0 Duration (T+A)- . Semester- 3 National Credit
Information About Course

Information
Goal, Content & Resources
Course Learning Outcomes
Relation with Program Learning Outcome
Week Plan
Student Workload - ECTS

Information

Code BİO524
Name Ageing Biology and Genetics
Semester . Semester
Duration (T+A) 3-0 (T-A) (17 Week)
ECTS 5 ECTS
National Credit 3 National Credit
Teaching Language Türkçe
Level Yüksek Lisans Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator Prof. Dr. HÜSNÜ ÜMİT LÜLEYAP


Course Goal

To examine the aging biology and genetics at the level of cell and organism

Course Content

Aging patterns, multiple factors effecting aging, opinions and theories related with genetics and endocrine DNA repair and free radicals, multiple effects of calorie restriction

Course Precondition

Resources

Notes



Course Learning Outcomes

Order Course Learning Outcomes
LO01 Knows aging patterns.
LO02 Knows the factors affecting aging
LO03 Knows the opinions and theories related with Genetics and Endocrine DNA repair and free radical.
LO04 Knows the multiple effects of calorie restriction.


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal To comprehend the structure and functions of cells and organelles which constitute the basic structure of life 5
PLO02 Bilgi - Kuramsal, Olgusal To recognize the functions of tissue and organ systems 4
PLO03 Bilgi - Kuramsal, Olgusal To examine the structure of genetic material 4
PLO04 Bilgi - Kuramsal, Olgusal To recognize genetic diseases and genes that cause these diseases 3
PLO05 Bilgi - Kuramsal, Olgusal To learn the structure of genes 4
PLO06 Bilgi - Kuramsal, Olgusal To define chromosome and gene mutations 4
PLO07 Bilgi - Kuramsal, Olgusal To classify heredity forms (autosomal dominant, autosomal recessive, gender-dependent dominant and recessive inheritance models) 3
PLO08 Bilgi - Kuramsal, Olgusal To use molecular and cytogenetic analysis 2
PLO09 Bilgi - Kuramsal, Olgusal To be able to explain the numerical and structural anomalies of autosomal and sex chromosomes 2
PLO10 Bilgi - Kuramsal, Olgusal To make DNA isolation from all kinds of tissues 2
PLO11 Bilgi - Kuramsal, Olgusal To prepare PCR 3
PLO12 Bilgi - Kuramsal, Olgusal To make and interpret agarose and polyacrylamide gel electrophoresis 2
PLO13 Bilgi - Kuramsal, Olgusal To measure the obtained DNA on the spectrophotometer 4
PLO14 Bilgi - Kuramsal, Olgusal To apply and interpret QF-PCR technique 2
PLO15 Bilgi - Kuramsal, Olgusal To make cell culture from blood, amnion, chorionic villus biopsy specimens and to obtain chromosome preparation 2
PLO16 Bilgi - Kuramsal, Olgusal To perform karyotype analysis of chromosome preparations and to recognize and interpret all human chromosomes 1
PLO17 Beceriler - Bilişsel, Uygulamalı To interpret a scientific article and to learn how to write a paper 1


Week Plan

Week Topic Preparation Methods
1 The evolutionary story of aging and death Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
2 The factors effecting aging Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
3 The genetics theory, telomere and aging Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
4 The effects of DNA damage and repair systems Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
5 Free radicals and their neutralization, the effect of neural system on the length of life Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
6 RNA destruction and aging Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
7 The effects of calorie restrictions Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Soru-Cevap, Tartışma, Alıştırma ve Uygulama
8 Mid-Term Exam Preparing multiple-choice questions Ölçme Yöntemleri:
Yazılı Sınav
9 Aging and DNA metilation Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
10 Aging and DNA metilation Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
11 Aging and apoptosis Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
12 Aging and apoptosis Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
13 Gene interactions related with aging Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
14 Lamina structure and aging diseases Preparing presentation, Preparing of lecture notes, Brain storming Öğretim Yöntemleri:
Soru-Cevap, Tartışma
15 Results and Discussion Brain storming, Revision Öğretim Yöntemleri:
Anlatım, Tartışma, Beyin Fırtınası
16 Term Exams Preparing multiple-choice questions Ölçme Yöntemleri:
Yazılı Sınav
17 Term Exams Preparing multiple-choice questions Ölçme Yöntemleri:
Yazılı Sınav


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 3 42
Out of Class Study (Preliminary Work, Practice) 14 3 42
Assesment Related Works
Homeworks, Projects, Others 3 12 36
Mid-term Exams (Written, Oral, etc.) 1 3 3
Final Exam 1 3 3
Total Workload (Hour) 126
Total Workload / 25 (h) 5,04
ECTS 5 ECTS