Trans557 Biomarkers and Precised Medicine (Z)

5 ECTS - 1-4 Duration (T+A)- . Semester- 3 National Credit

Information

Code Trans557
Name Biomarkers and Precised Medicine (Z)
Term 2022-2023 Academic Year
Semester . Semester
Duration (T+A) 1-4 (T-A) (17 Week)
ECTS 5 ECTS
National Credit 3 National Credit
Teaching Language İngilizce
Level Yüksek Lisans Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator


Course Goal / Objective

From genomic analysis and genetic counseling to cancer biomarkers, from risk assessment of chronic diseases to the understanding of gene-environment interactions, from pharmacogenomics to multi-omics data integration, the course will walk students through the many aspects of precision medicine, from the bench to the bedside and to population health

Course Content

This course will provide students with the key knowledge and tools to understand the fundamentals and practical implications of precision medicine, its opportunities and challenges. It will address precision-medicine era diagnostics, treatment selection, genetic counseling, public health interventions, and biomedical research. It will also deal with data science and ethical issues.

Course Precondition

Resources

Notes



Course Learning Outcomes

Order Course Learning Outcomes
LO01 The students who attend this course will understand the state of art of and explain current challenges in diagnosis, follow-up and therapy of diseases in the selected case scenarios and can tell the reasons why biomarkers and personalized medicine is needed.
LO02 They will learn the procedures to discover biomarkers and , how to analyze their efficacy
LO03 Students will write a sample protocol in their choice of area to develop and test a biomarker


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal Develops and deepens knowledge in the field of translational medicine to the proficiency level based on bachelor-level qualifications. 5
PLO02 Bilgi - Kuramsal, Olgusal Conceives the interdisciplinary interaction in which the field is related to translational medicine 5
PLO03 Bilgi - Kuramsal, Olgusal Knows the information technologies, technical equipment, and field-specific devices and instruments at the level required by the field of Translational Medicine. 5
PLO04 Bilgi - Kuramsal, Olgusal Knows statistics as a tool that is constantly used in studies in the field of Translational Medicine, and uses relevant software effectively. 5
PLO05 Beceriler - Bilişsel, Uygulamalı Uses of theoretical and practical knowledge within the field at a proficiency level. 5
PLO06 Beceriler - Bilişsel, Uygulamalı Interprets the knowledge about the field by integrating the information gathered from different disciplines and formulates new knowledge. 5
PLO07 Beceriler - Bilişsel, Uygulamalı Makes necessary investigations by using tools, devices, and instruments required for knowledge and technologies about translational medicine and related disciplines at an advanced level; develops a new and creative solution (device, method, treatment, drug) for the problems. 4
PLO08 Beceriler - Bilişsel, Uygulamalı Solves the problem faced related to the field by using research methods. 3
PLO09 Beceriler - Bilişsel, Uygulamalı Plans and conducts an experimental study. 3
PLO10 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Takes responsibility and develops new strategic solutions as a team member in order to solve unexpected complex problems faced within the applications in the field, evaluates the results, and applies when necessary. 4
PLO11 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Conducts scientific studies in translational medicine and related fields independently or as a team member. 4
PLO12 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Publishes a scientific paper in a national journal or presents it at a scientific meeting. 3
PLO13 Yetkinlikler - Öğrenme Yetkinliği Evaluates knowledge and skills acquired at proficiency level in the field with a critical approach and direct the learning. 5
PLO14 Yetkinlikler - Öğrenme Yetkinliği Applies the principles of advanced professional development and lifelong learning in the field of Translational Medicine. 5
PLO15 Yetkinlikler - İletişim ve Sosyal Yetkinlik Communicates current developments and studies within the field to both professional and non-professional groups systematically using written, oral and visual techniques by supporting quantitative and qualitative data. 5
PLO16 Yetkinlikler - İletişim ve Sosyal Yetkinlik Communicates and discusses orally, in writing, and visually with peers by using a foreign language at least at a level of European Language Portfolio B2 General Level. 5
PLO17 Yetkinlikler - Alana Özgü Yetkinlik Develops strategy, policy, and implementation plans on the issues related to the field and assess the findings within the frame of quality processes and ethics. 5


Week Plan

Week Topic Preparation Methods
1 Understanding Biomarkers and Precised Medicine terminology Öğretim Yöntemleri:
Anlatım
2 Human genome variabilty and phenotype consequences Öğretim Yöntemleri:
Tartışma
3 New generation sequencing and liquid biopsy techniques Öğretim Yöntemleri:
Deney / Laboratuvar
4 Rare genetic disorder and precision medicine Öğretim Yöntemleri:
Grup Çalışması
5 Biomarker discover methodologies Öğretim Yöntemleri:
Anlatım
6 Article presentations related to biomarker discovery Öğretim Yöntemleri:
Grup Çalışması
7 Case study Öğretim Yöntemleri:
Grup Çalışması
8 Mid-Term Exam Ölçme Yöntemleri:
Sözlü Sınav
9 Liquid chromatography and mass spectrometry studies - I Öğretim Yöntemleri:
Deney / Laboratuvar
10 Liquid chromatography and mass spectrometry studies - II Öğretim Yöntemleri:
Deney / Laboratuvar
11 Biomarker discovery proposal workshop - I Öğretim Yöntemleri:
Grup Çalışması
12 Stutents' Proposal presentations Öğretim Yöntemleri:
Bireysel Çalışma
13 Biomarker discovery proposal workshop - II Öğretim Yöntemleri:
Bireysel Çalışma
14 Evidence-Based Precision Medicine Öğretim Yöntemleri:
Grup Çalışması
15 New Technologies and Personalized Health: Opportunities and Challenges Öğretim Yöntemleri:
Tartışma
16 Term Exams
17 Term Exams

Update Time: 11.10.2022 11:45