BLS403 Epigenetics

4 ECTS - 2-0 Duration (T+A)- 7. Semester- 2 National Credit

Information

Code BLS403
Name Epigenetics
Term 2023-2024 Academic Year
Semester 7. Semester
Duration (T+A) 2-0 (T-A) (17 Week)
ECTS 4 ECTS
National Credit 2 National Credit
Teaching Language Türkçe
Level Lisans Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator Prof. Dr. ELİF ORUÇ
Course Instructor Prof. Dr. ELİF ORUÇ (A Group) (Ins. in Charge)


Course Goal / Objective

This course aims to understand the assessment of epigenetic mechanisms of gene regulation, epigenetic controls cause to human diseases and their novel therapies.

Course Content

The history of epigenetics, mechanisms of epigenetic processes, methods used and model organism studies, epigenetic-related human diseases, epigenome and epigenetic therapy constitute the content of this course.

Course Precondition

None

Resources

Epigenetics (2015) : C. David Allis and Manika Lancher, Cold Spring Harbor, NY, 984 p.

Notes

Epigenetics in Biolgy and Medicine (2009), Manel Esteller, CRC Press, Taylor and Francis Group, LLC, 316 p.


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Explains epigenetic mechanisms
LO02 Explaines the relationship between epigenetics and human diseases.
LO03 Evaluates and Discuss the methodologies in epigenetics field
LO04 Explains epigenetic treatment methods


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal Explain the basic concepts and principles in biology 4
PLO02 Bilgi - Kuramsal, Olgusal The knowledge gained in the field of biology combine with information from other sciences. 3
PLO03 Bilgi - Kuramsal, Olgusal Identifies problems in the field of biology and apply methods for their solution 4
PLO04 Bilgi - Kuramsal, Olgusal Describes the method of producing scientific knowledge in the field of biology 3
PLO05 Bilgi - Kuramsal, Olgusal They will receive information on the biology area, in order to classify it uses and purposes. 3
PLO06 Bilgi - Kuramsal, Olgusal They use advanced theoretical and practical knowledge that obtain in biology field.
PLO07 Bilgi - Kuramsal, Olgusal They are Field-related issues can inform the relevant persons and institutions, They share ideas and problems relating to suggestions as the written, oral and Visual to expert or transfer to non-experts. 3
PLO08 Bilgi - Kuramsal, Olgusal They can take responsibility as individuals and team members to solve unpredictable problems encountered in applications related to the field. 4
PLO09 Bilgi - Kuramsal, Olgusal they can take an active role as a member of the execution team the planning of projects related to the field.
PLO10 Beceriler - Bilişsel, Uygulamalı They know that life-long learning process and act accordingly. 4
PLO11 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği They will increase the knowledge and experience outside major issues with specific elective courses in different fields of biology. 3
PLO12 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği They speak English enough to communicate with colleagues to understand the basic concepts of biology.
PLO13 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği They both with colleagues, as well as areas with non-person establishes ethical uses of information and communication technology. In addition to professional development, in line with the interests and abilities of scientific, social, constantly improves itself by identifying learning needs in cultural and artistic fields. 4
PLO14 Yetkinlikler - Öğrenme Yetkinliği They assesses developments in biology versatile using scientific methods and techniques 5
PLO15 Yetkinlikler - Öğrenme Yetkinliği They know the importance of personal development and enforces the need.


Week Plan

Week Topic Preparation Methods
1 History of epigenetics, Why we need epigenetics Lecture Notes, Literature browsing and reading Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
2 Epigenetic mechanisms: DNA Methylation Lecture Notes Literature browsing and reading Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
3 Epigenetic mechanisms: Histone Modification Lecture Notes, Literature browsing and reading Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
4 Epigenetic technology: DNA methylation analysis Lecture Notes, Literature browsing and reading Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
5 Epigenetic technology: Chromosome immunoprecipitation Lecture Notes, Literature browsing and reading Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
6 Model organisms used in epigenetic studies Lecture Notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
7 Metabolism and epigenetics Lecture Notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
8 Mid-Term Exam Literature browsing and reading Lecture notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
9 Stem cell and cellular differentiation, X chromosome inactivation, genomic imprinting Lecture Notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
10 Diet, impact of environmental agents on the epigenome, population pharmacoepigenomics Lecture Notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
11 Cancer epigenetics Lecture Notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
12 Epigenetics and immunity Lecture Notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
13 Epigenetics and epigenomics Lecture Notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
14 Epigenetic therapy Lecture Notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
15 Epigenetics and epidemiology Lecture Notes Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
16 Term Exams Lecture notes Ölçme Yöntemleri:
Yazılı Sınav, Ödev, Proje / Tasarım
17 Term Exams Lecture notes Ölçme Yöntemleri:
Ödev, Proje / Tasarım, Yazılı Sınav


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 2 28
Out of Class Study (Preliminary Work, Practice) 14 2 28
Assesment Related Works
Homeworks, Projects, Others 2 4 8
Mid-term Exams (Written, Oral, etc.) 1 15 15
Final Exam 1 15 15
Total Workload (Hour) 94
Total Workload / 25 (h) 3,76
ECTS 4 ECTS

Update Time: 09.05.2023 05:06