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Information
| Code | BFZ500 |
| Name | Cell and tissue biophysics-1 |
| Term | 2023-2024 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-3 (T-A) (17 Week) |
| ECTS | 7 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. AYKUT PELİT |
Course Goal / Objective
Explain bioelectrical phenomena in cell, tissue and organism by physical law and biophysical methods
Course Content
Membrane potential models, Fixed-electric field Membrane model, obtaining Nernst and Hodgkin-Huxley-Katz Equations, Hodgkin-Huxley (HH) dice model, Membrane electric equivalent circuit model, Undercoat events, single fiber and fiber bundle action potentials, extracellular and superficial potentials. EMG, ECG, EEG
Course Precondition
There is no prerequisite for the lesson
Resources
Lecture notes (For Medical Faculty Students - İsmail Günay) Biophysics (Ferit Pehlivan) Biophysics (Gürbüz Çelebi) Internet Search
Notes
Internet Research
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Learn the structure of the membrane and dice models |
| LO02 | Learns the formation of membrane potential |
| LO03 | Calculates ion equilibrium potential using Nernst equilibrium equation |
| LO04 | Calculates cell membrane steady-state potential with GHK equation |
| LO05 | Students will be able to apply the basic principles learned in biophysics to the living system. |
| LO06 | Knows the potential and EMG signals |
| LO07 | Learn the physical basis of ECG |
| LO08 | Learn the physical basis of EEG |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Learns basic information about the field | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Sets up and works experimental setups in the laboratory | 3 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Prepares a project proposal on its own | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Plans an experimental study | 2 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Reports the research result | |
| PLO06 | Bilgi - Kuramsal, Olgusal | Interpret the research findings | 2 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Has the analytical thinking mechanism related to the field, Reaches reliable information. Creates and writes a research project, works and researches based on ethical values. | 2 |
| PLO08 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | She/he systematically transfers the theoretical knowledge she has researched to the audience. | 1 |
| PLO09 | Yetkinlikler - Öğrenme Yetkinliği | Have a scientific thinking systematic in relation to their profession. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Cell potential | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 2 | Stationary electric field dice model | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 3 | Nernst and Hodgkin-Huxley-Katz Equations | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 4 | Membrane electrical equivalent circuit model | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 5 | Threshold events | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 6 | Single fiber and nerve bundle action potentials | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 7 | Extracellular and superficial potentials | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 8 | Mid-Term Exam | related topics read from books and literature | Öğretim Yöntemleri: Anlatım, Tartışma, Alıştırma ve Uygulama |
| 9 | superficial and volume conductive potentials | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 10 | Homework2 | related topics read from books and literature | Öğretim Yöntemleri: Anlatım, Tartışma, Alıştırma ve Uygulama |
| 11 | Electrocardiography | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 12 | Homework3 | related topics read from books and literature | Öğretim Yöntemleri: Anlatım, Tartışma, Alıştırma ve Uygulama |
| 13 | Electrocardiography measurements | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 14 | Homework4 | related topics read from books and literature | Öğretim Yöntemleri: Anlatım, Tartışma, Alıştırma ve Uygulama |
| 15 | Electroencephalography | Reads the relevant chapter before class | Öğretim Yöntemleri: Anlatım, Tartışma, Problem Çözme |
| 16 | Term Exams | Studying the lessons taught throughout the semester | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
| 17 | Term Exams | Studying the lessons taught throughout the semester | Ölçme Yöntemleri: Yazılı Sınav, Ödev, Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 3 | 6 | 18 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 28 | 28 |
| Total Workload (Hour) | 170 | ||
| Total Workload / 25 (h) | 6,80 | ||
| ECTS | 7 ECTS | ||