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Information
| Code | BTE026 |
| Name | In Vitro and In Vivo Studies in Molecular Pharmacology |
| Term | 2023-2024 Academic Year |
| Term | Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. NACİYE DÖNDAŞ |
| Course Instructor |
1 |
Course Goal / Objective
In this course, it is aimed to teach the general principles of in vivo and in vitro methods used in molecular pharmacology studies, and pharmacogenetic analysis, immunohistochemical methods and related strategies.
Course Content
Introduction to molecular pharmacology, what is in vitro and in vivo, in vitro and in vivo tests, general principles in in vitro and in vivo studies, in vitro and in vivo methods; preparation techniques of isolated tissues, pharmacogenetic analysis, immunohistochemical methods, in vivo and in vitro methods in cancer research.
Course Precondition
No Prerequisites
Resources
1. John Dickenson, Fiona Freeman, Chris Lloyd Mills, Shiva Sivasubramaniam, Christian Thode, Molecular Pharmacology: From DNA to Drug Discovery, 2013 John Wiley & Sons, Ltd. 2. Saleha Shahar, Siti Pauliena Mohd Bohari, In Vitro and In Vivo Techniques with Consideration of Biological System, 2020, Penerbit UTM Press; https://www.e-sentral.com/book/info/332404
Notes
Scientific database
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | The student knows and tells in vitro and in vivo tests. |
| LO02 | Knows and explains the preparation techniques of isolated tissues. |
| LO03 | Tells pharmacogenetic analysis and immunohistochemical methods. |
| LO04 | Knows and explains in vivo and in vitro methods in cancer research. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on the undergraduate level qualifications, develops and deepens the knowledge in the same or different field at the level of expertise and analyzes and interprets them using statistical methods. | 4 |
| PLO02 | Beceriler - Bilişsel, Uygulamalı | To identifiy the interdisciplinary interaction of the field and to solve use of the methods. | 3 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Interpret the knowledge gained in the field by integrating the information from different disciplines and creates new information | 3 |
| PLO04 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Develops new strategic approaches for solving complex problems that are encountered in applications related to the field. | 3 |
| PLO05 | Yetkinlikler - Öğrenme Yetkinliği | To teach the social, scientific, cultural and ethical values during the collection, interpretation, implementation and announcement of the data related to the field. | 4 |
| PLO06 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | To solve the problems encountered in the field and cominicate by using research methods. | 4 |
| PLO07 | Yetkinlikler - Alana Özgü Yetkinlik | To gain the ability to develop and deepen the knowledge in the field of biotechnology | |
| PLO08 | Bilgi - Kuramsal, Olgusal | Knows the ethical rules to be considered while obtaining biotechnological products. | 5 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Establishes functional interaction by using strategic decision-making processes in solving the problems encountered in the field. | |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | Gains the ability to develop and deepen their knowledge in the field of biotechnology at the level of expertise. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to molecular pharmacology | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | What is in vitro and in vivo | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | In vitro test-1 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | In vitro tests-2 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | In vivo tests-1 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | In vivo tests-2 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | General principles in in vitro and in vivo studies | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Preparation techniques of isolated tissues-1 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 9 | Preparation techniques of isolated tissues-2 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Pharmacogenetic analyzes-1 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Pharmacogenetic analyzes-2 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Immunohistochemical methods-1 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Immunohistochemical methods-2 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | In vitro and in vivo methods in cancer research-1 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | In vitro and in vivo methods in cancer research-2 | Books and scientific databases | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Midterm exam | Ölçme Yöntemleri: Yazılı Sınav |
|
| 17 | Semester final exam | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 5 | 70 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 15 | 15 |
| Final Exam | 1 | 30 | 30 |
| Total Workload (Hour) | 157 | ||
| Total Workload / 25 (h) | 6,28 | ||
| ECTS | 6 ECTS | ||