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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| Code | MİK600 |
| Name | Special Virology (C) |
| Term | 2026-2027 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 4-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 4 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. FÜGEN YARKIN |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
The aim of this course is to provide students with fundamental principles of medical virology, to understand the molecular biology and pathogenesis of viruses, and to gain knowledge about the diagnosis and evaluation of clinically important viral infections.
Course Content
This course covers the classification, structure, replication mechanisms, and pathogenesis of medically important viruses. Molecular characteristics of DNA viruses, their interactions with host cells, immune evasion strategies, and associated diseases are discussed. Basic virological diagnostic methods are also introduced.
Course Precondition
Basic knowledge of Microbiology and Immunology is recommended.
Resources
Jawetz, Melnick & Adelberg's Medical Microbiology Medical Microbiology by Murray, Rosenthal and Pfaller Sherris Medical Microbiology
Notes
• Fields Virology Principles of Virology by Flint et al. World Health Organization ve Centers for Disease Control and Prevention kılavuzları Recent review articles in peer-reviewed journals
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explains the basic properties and classification of viruses. |
| LO02 | Describes the structure and genome organization of DNA viruses. |
| LO03 | Explains the replication mechanisms of DNA viruses. |
| LO04 | Interprets virus–host cell interactions and viral pathogenesis. |
| LO05 | Identifies clinical manifestations caused by DNA viruses. |
| LO06 | Explains the mechanisms of oncogenesis of oncogenic DNA viruses (especially HPV). |
| LO07 | Describes host immune responses and viral immune evasion strategies. |
| LO08 | Compares basic laboratory diagnostic methods used for DNA viruses (e.g., PCR, serology). |
| LO09 | Explains antiviral treatment approaches for DNA viral infections. |
| LO10 | Interprets virological data using current scientific literature. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Beceriler - Bilişsel, Uygulamalı | Having acquired technical skills through laboratory studies, being able to access information, conduct research, plan experiments, solve problems, interpret experimental results, make presentations, develop strategies on microbiology-related issues | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Having received a quality microbiology education at a standard accepted in international platforms, having broadened scientific horizons and being preferred in many sectors related to microbiology, being competent in microbiology | 2 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Isolates infectious agents | |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Performs the steps of identifying infectious agents | 1 |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Knowing and applying laboratory methods used in general bacteriology, virology, parasitology, mycology and immunology at theoretical and practical levels | 1 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Being aware of ethical values and problems in the field of microbiology | |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Ability to make critical evaluations on published research in the field of microbiology | |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Gaining the competence to present a research conducted in the field of microbiology in written, oral and visual form and prepare it for publication | |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Having acquired research and career ethics | |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | Having deepened knowledge on specific subjects studied (thesis study) |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to virology, general properties of viruses | Review of basic properties of viruses | Öğretim Yöntemleri: Anlatım |
| 2 | Virus classification (Baltimore classification) and taxonomy | Reading virus classification (Baltimore system) | Öğretim Yöntemleri: Anlatım |
| 3 | Viral structure and genome organization (DNA vs RNA comparison) | Study of viral structure and genome organization | Öğretim Yöntemleri: Anlatım |
| 4 | Viral replication mechanisms (with emphasis on DNA viruses) | Review of viral replication steps | Öğretim Yöntemleri: Anlatım |
| 5 | Virus–host cell interaction, pathogenesis and immune response | Review of virus–host interaction and immune response | Öğretim Yöntemleri: Anlatım |
| 6 | Herpesviridae I (HSV-1, HSV-2, VZV) | Basic features of Herpesviridae family | Öğretim Yöntemleri: Anlatım |
| 7 | Herpesviridae II (EBV, CMV, HHV-6/7/8) | Advanced Herpesviridae members (EBV, CMV) | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Preparation for Exam | Öğretim Yöntemleri: Anlatım |
| 9 | Papillomaviridae (HPV) – with emphasis on oncogenesis | Reading on HPV and oncogenic viruses | Öğretim Yöntemleri: Anlatım |
| 10 | Polyomaviridae (BK, JC) | Pre-reading on Polyomaviridae | Öğretim Yöntemleri: Anlatım |
| 11 | Adenoviridae | Basic information on Adenoviridae | Öğretim Yöntemleri: Anlatım |
| 12 | Parvoviridae | Basic information on Parvoviridae | Öğretim Yöntemleri: Anlatım |
| 13 | Poxviridae | Preparation on Poxviridae | Öğretim Yöntemleri: Anlatım |
| 14 | Hepadnaviridae (HBV) | HBV life cycle and structure | Öğretim Yöntemleri: Anlatım |
| 15 | Diagnostic methods in DNA viruses (PCR, serology, viral load) | Diagnostic methods in DNA viruses | Öğretim Yöntemleri: Anlatım |
| 16 | Term Exams | Preparation for Exam | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 122 | ||
| Total Workload / 25 (h) | 4,88 | ||
| ECTS | 5 ECTS | ||