BİO607 Cell Cycle and Control

5 ECTS - 3-0 Duration (T+A)- . Semester- 3 National Credit
Information About Course

Information
Goal, Content & Resources
Course Learning Outcomes
Relation with Program Learning Outcome
Week Plan
Student Workload - ECTS

Information

Code BİO607
Name Cell Cycle and Control
Semester . Semester
Duration (T+A) 3-0 (T-A) (17 Week)
ECTS 5 ECTS
National Credit 3 National Credit
Teaching Language Türkçe
Level Doktora Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator Prof. Dr. AYFER PAZARBAŞI


Course Goal

To present and tell cell signaling, cell cycle, cell death, cell renewal and molecular basis of cancer biolgy.

Course Content

Cell signaling, Molecules and receptors of signaling, Intracelular signaling with hydrophobic and hydrophylic receptors, the role of cell skeleton in cell signaling, Signal network, Cell cycle, Eukaryotic cell cycle, Regulators of cell cycle, Cell death and renewal, Programed cell death, Embryonic stem cells and therapeutic cloning, cancer, causes and progress of cancer, tumor viruses, oncogenes, tumor suppressor genes, molecular approach in cancer treatment.

Course Precondition

There is no precondition for this lesson.

Resources

Kasap H.(Ed.), M. Kasap, O. Demirhan, D. Alptekin, Ü. Lüleyap, A. Pazarbaşı, A.Irfan Güzel. Tıbbi Biyoloji ve Genetik, Nobel Kitabevi; ISBN: 978-605-397-059-0, 421-435, Adana (2016).

Notes

Cooper GM, Hausman RE. 2007. The Cell, A Molecular Approach. Fourth Ed., ASM Press, Washington DC.


Course Learning Outcomes

Order Course Learning Outcomes
LO01 The student explains basic cell signal molecules, reseptors and signaling pathways.
LO02 The student tells eukaryotic cell cycle and molecular control mechanisms.
LO03 The student outlines programed and other cell death pathways.
LO04 The student expreses the relationship between cell skeleton and signaling.
LO05 The student describes stem cells with every aspect.
LO06 The student outlines therapeutic cloning.
LO07 The student explains the relationship between cancer progress and tumor viruses, oncogenes and tumor suppressor genes.
LO08 The student expreses the significance of signaling in development and differentiation.
LO09 The student outlines normal cellular pathways.
LO10 The student comprehends intracellular signaling pathways.
LO11 The student explains the molecular aspects of cancer treatment.


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal To make and interpret Medical Genetics, Molecular Genetics and Cytogenetic analyzes 1
PLO02 Bilgi - Kuramsal, Olgusal To have information about genetic diseases 3
PLO03 Bilgi - Kuramsal, Olgusal To have knowledge of Molecular Cell Biology 5
PLO04 Bilgi - Kuramsal, Olgusal To apply fluorescence in-situ hybridization (FISH) technique
PLO05 Bilgi - Kuramsal, Olgusal To make DNA isolation and PCR of all kinds of tissue
PLO06 Bilgi - Kuramsal, Olgusal To make cell culture of all kinds of tissue (blood, amniotic fluid, chorionic villus biopsy)
PLO07 Bilgi - Kuramsal, Olgusal To do cytogenetic analysis by recognizing human chromosomes separately
PLO08 Bilgi - Kuramsal, Olgusal To make QF-PCR and to interpret the results
PLO09 Bilgi - Kuramsal, Olgusal To have the knowledge and skills to teach Medical Biology and Genetics Courses in Medical Faculties
PLO10 Bilgi - Kuramsal, Olgusal To write and implement a research project on his/her own
PLO11 Bilgi - Kuramsal, Olgusal To write an article by collecting the information obtained at the end of the research
PLO12 Yetkinlikler - Öğrenme Yetkinliği To organize laboratory courses of Medical Biology and Genetics courses at undergraduate level


Week Plan

Week Topic Preparation Methods
1 Eukaryotic cell cycle Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Tartışma
2 Regulation of eukaryotic cell cycle Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Tartışma
3 The stages of division Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Grup Çalışması
4 Meiosis and fertilization Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Tartışma
5 Molecules and receptors of cell signaling Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Beyin Fırtınası
6 Types of cell signaling Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Tartışma
7 Intracellular signaling pathways Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Tartışma
8 Mid-Term Exam Preparation a presentation Ölçme Yöntemleri:
Performans Değerlendirmesi
9 Cell skeleton and signaling Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Grup Çalışması
10 Cell signaling in development and differentiation. Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Tartışma
11 Programed cell death and regulation of programed cell death Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Tartışma
12 The relationship between cancer and cell signaling Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Tartışma
13 The relationship between cancer and cell cycle Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Tartışma
14 Normal cellular pathways Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Tartışma
15 Stem cells and protecting adult tissues Literature review and reading the subject Öğretim Yöntemleri:
Anlatım, Beyin Fırtınası
16 Term Exams Preparation multiple choice and classical questions Ölçme Yöntemleri:
Yazılı Sınav, Performans Değerlendirmesi
17 Term Exams Preparation multiple choice and classical questions Ölçme Yöntemleri:
Yazılı Sınav, Performans Değerlendirmesi


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 3 42
Out of Class Study (Preliminary Work, Practice) 14 3 42
Assesment Related Works
Homeworks, Projects, Others 3 15 45
Mid-term Exams (Written, Oral, etc.) 1 2 2
Final Exam 1 2 2
Total Workload (Hour) 133
Total Workload / 25 (h) 5,32
ECTS 5 ECTS