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Information
| Code | ECF424 |
| Name | Clinical Toxicology |
| Term | 2024-2025 Academic Year |
| Semester | 8. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 2 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi Göksun DEMİREL |
| Course Instructor |
1 2 |
Course Goal / Objective
Comprehends the importance of clinical toxicology. Explains the duties of databases and poison control centers related to clinical toxicology, compares local and systemic antidote therapy. discuss pesticide poisonings, drug specific poisonings and their treatments.
Course Content
General knowledge of clinical toxicology and toxic responses of target organs; general principles of treatment in poisonings; analgesic and anti-inflammatory drugs; anticholinergic and neuroleptic drugs; addictive substances; sympathomimetics; sedative/hypnotics; cardiovascular drugs; hallucinogenic substances; toxic gases; pesticides (insecticides, rodenticides, herbicides); alcohols; toxicity of certain groups of drugs and xenebiotics, such as household chemicals.
Course Precondition
None
Resources
1. Clinical Toxicology: Principles and Mechanisms, Second Edition, Frank A. Barile, CRC Press, 2010 2. Clinical Toxicology in Emergency, Assoc. Salih Satar Adana Nobel Bookstore, Adana - 2009
Notes
1. Toxicology Laboratory Book, Prof.Dr. Nevin Vural, Ankara University Faculty of Pharmacy Publications Ankara-2000
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explain drug interaction. |
| LO02 | List the drug interactions that occur frequently. |
| LO03 | Discuss pharmacodynamic and pharmacokinetic interactions. |
| LO04 | Explains the effects of nutritions on the drugs. |
| LO05 | Explains drugs and herbal preparats interactions. |
| LO06 | Explains the toxic effects of NSAI drugs. |
| LO07 | Explain the toxic mechanism, poisoning symptoms and poisoning treatment of acetaminophen. |
| LO08 | Explain the toxic mechanism, poisoning symptoms and poisoning treatment of salisalats. |
| LO09 | Explains the toxic effects of chemotherapeutic drugs. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Have sufficient knowledge in pharmaceutical field and develop the knowledge. | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends professional knowledge with ethical responsibility through current laws and legislation. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Provides consultancy service to patients, community and health care personnel and evaluates advanced knowledge and skills with a critical approach. | 2 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 1 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Have the knowledge and skills to help provide patient-oriented pharmacy applications and individualized pharmaceutical care by learning the basics of Clinical Pharmacy, | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 1 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Integrates and develops professional knowledge via different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 1 |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Use effectively the concepts and applications of basic sciences and basic medical sciences in the field of medicine and pharmacy and update the information. | |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates effectively in writing and speaking. | |
| PLO10 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Practices the profession in accordance with Atatürk's principles and reforms, equipped with universal knowledge, uses Turkish correctly and knows at least one foreign language. | |
| PLO11 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Be an example to society withexternal appearance, demeanor, attitude and behavior for the other professionals and society and with professional identity | |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | |
| PLO13 | Yetkinlikler - Alana Özgü Yetkinlik | Interprets information about current health and treatment problems and attends meeting on related matters . Plays an active role in community health. | 2 |
| PLO14 | Yetkinlikler - Alana Özgü Yetkinlik | Acquires basic information about diseases, makes decisions about the drugs used in treatment in accordance with rational drug use. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Drug Interactions and Toxilogical Results | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 2 | Toxic effects of non-steroidal anti-inflammatory drugs | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Toxic effects of Antibiotics | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 4 | Toxic effects of anti-hypertensive and cardiovascular system drugs | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım, Tartışma |
| 5 | Toxic effects of antidepressant and antiepileptic drugs | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 6 | Toxic effects of vitamins and chemotherapeutic drugs | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 7 | Toxic effects of anti-diabetic and thyroid drugs | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Lesson Repetition Subject Repetition An overview | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Toxicity of Volatile Compounds, Intoxications with Domestic Chemicals | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Heavy Metal Toxicity | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım |
| 11 | Selective Toxicity and Pesticide Toxicology | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | Target Organ Toxicity | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | Toxins and Toxic Compounds in Foods | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | Animal origin and herbal Poisoning, Mushroom Poisoning | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 15 | Toxic Effects of Excipients | Reading the Related Section of the Textbook | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 16 | Term Exams | Lesson Repetition Subject Repetition An overview | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Lesson Repetition Subject Repetition An overview | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 1 | 14 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 4 | 4 |
| Final Exam | 1 | 8 | 8 |
| Total Workload (Hour) | 54 | ||
| Total Workload / 25 (h) | 2,16 | ||
| ECTS | 2 ECTS | ||