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Information
| Code | BB0043 |
| Name | Advance Molecular Genetic |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 4-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 4 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator |
Course Goal / Objective
To teach advance and current concepts and topics in genetics.
Course Content
Fundamentals of Advanced Molecular Genetics
Course Precondition
There are no prerequisites for the course.
Resources
Lecture notes, books, research articles, periodicals on the subject
Notes
Internet resources obtained from scientific search engines
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Repeats basic molecular genetics concepts and topics from nucleic acids to DNA, RNA and protein synthesis and explains them |
| LO02 | Knows the process before next generation sequencing of isolated samples and explains it |
| LO03 | Learns next-generation sequencing and library construction and explains them |
| LO04 | Learn the basic concepts of bioinformatics analysis after next generation sequencing and explains them |
| LO05 | Learns the verification methods of the detected loci and explains them |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To be able to develop, deepen, and to reach the original definitions that will bring innovation to the field with the original thinking and/or research of the current and advanced knowledge in his / her field based on his / her master's qualifications. | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends interdisciplinary interaction related to horticultural plants; achieves original results using information that requires expertise in analyzing, synthesizing and evaluating new and complex ideas | 2 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Evaluates and uses new information in his / her field with a systematic approach | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Can develop a new idea, method, design and/or application, or apply a known idea, method, design and/or application to a different field; can research, comprehend, design and apply an original topic | |
| PLO05 | Bilgi - Kuramsal, Olgusal | Make critical analysis, synthesis and evaluation of new and complex ideas | 2 |
| PLO06 | Bilgi - Kuramsal, Olgusal | To be able to use research methods in his / her field of study | 3 |
| PLO07 | Bilgi - Kuramsal, Olgusal | To develop a new idea, method, design and/or application, or apply a well-known idea, method, design and/or application to a different field independently of the original work to contribute to the progress in the field | 2 |
| PLO08 | Bilgi - Kuramsal, Olgusal | To be able to publish at least one scientific article in national and international refereed journals, or to produce or interpret an original work, to be able to extend the limits of knowledge in the field. | 2 |
| PLO09 | Bilgi - Kuramsal, Olgusal | To Be able to lead in environments that require solving interdisciplinary problems, use problem solving skills in interdisciplinary studies | |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Develops new ideas and methods related to his / her field by using high-level mental processes such as creative and critical thinking, problem solving and decision making | 2 |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | In the national and international platforms, they present original views in the discussion of issues related to the field of local and foreign experts, they can defend these views, examine, develop and change the norms leading to social relations and these relations from a critical point of view; they can communicate effectively showing their competence in the field. | 2 |
| PLO12 | Yetkinlikler - Öğrenme Yetkinliği | Specialized in special topics in his / her field | 2 |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | To be an information society in which the society lives, to be able to maintain it, to contribute to the solution of the social, scientific, cultural and ethical problems encountered. | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | advence genetic concepts | Reading of the papers about the lecture | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Laboratuar works before next generation secuencing | Reading of the papers about the lecture | Öğretim Yöntemleri: Anlatım |
| 3 | Next generation sequencing and library construction | Reading of the papers about the lecture | Öğretim Yöntemleri: Anlatım |
| 4 | chromosome mutations | Reading of the papers about the lecture | Öğretim Yöntemleri: Anlatım |
| 5 | The analysis of quality in NGS data | Reading of the papers about the lecture | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | The alignment of the reads in genome | Reading of the papers about the lecture | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 7 | Detection of the variants | Reading of the papers about the lecture | Öğretim Yöntemleri: Anlatım |
| 8 | Mid term | Reading textbooks and notes related to the course | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
| 9 | The analysis of the gene expression | Reading of the papers about the lecture | Öğretim Yöntemleri: Anlatım |
| 10 | Detection of the differential expression genes | Reading of the papers about the lecture | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 11 | The verification of the genes by qPCR | Reading of the papers about the lecture | Öğretim Yöntemleri: Anlatım |
| 12 | The collection of the obtained data from analysis | Reading of the papers about the lecture | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 13 | The evaluation of the lesson | Reading of the papers about the lecture | Öğretim Yöntemleri: Beyin Fırtınası |
| 14 | The repetition of the topics | Repeats of the lesson texts | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 15 | The repetition of the topics 2 | Repeats of the lesson texts | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 16 | General repetition | General repetition of the lesson topics | Öğretim Yöntemleri: Tartışma, Soru-Cevap |
| 17 | Final term | General repetition of the lesson topics | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 28 | 28 |
| Total Workload (Hour) | 152 | ||
| Total Workload / 25 (h) | 6,08 | ||
| ECTS | 6 ECTS | ||