BL494 Toxicology

4 ECTS - 2-0 Duration (T+A)- 8. Semester- 2 National Credit

Information

Code BL494
Name Toxicology
Term 2024-2025 Academic Year
Semester 8. Semester
Duration (T+A) 2-0 (T-A) (17 Week)
ECTS 4 ECTS
National Credit 2 National Credit
Teaching Language Türkçe
Level Lisans Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator Prof. Dr. ELİF ORUÇ
Course Instructor
1 2
Prof. Dr. ELİF ORUÇ (A Group) (Ins. in Charge)


Course Goal / Objective

The aim of this course is to provıde knowledge and understanding about the principles of toxicology, xenobiotic metabolism. Also it will be discussed on cell damage together with biochemical and molecular toxicity mechanisms of xenobiotics.

Course Content

This course includes; Principles of toxicology, toxic effect mechanisms of xenobiotics, cell damage and protective mechanisms

Course Precondition

None

Resources

Casarett and Doull's Principles of Toxicology

Notes

Toxicology (Nevin Yıldırım, Ankara University)


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Understands the general principles of toxicology, absorption, distribution, metabolism, side of action and excretion of toxic substance
LO02 Explains toxic effect mechanisms of xenobiotics
LO03 have detail information about cell damage and protective mechanisms
LO04 classified the detail information about hepatotoxicity
LO05 have detail information about neurotoxicity
LO06 Explain hydroxylation reactions
LO07 Explain Phase II Conjugation reactions
LO08 Explain kidney toxicity


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal Explain the basic concepts and principles in biology 4
PLO02 Bilgi - Kuramsal, Olgusal The knowledge gained in the field of biology combine with information from other sciences.
PLO03 Bilgi - Kuramsal, Olgusal Identifies problems in the field of biology and apply methods for their solution
PLO04 Bilgi - Kuramsal, Olgusal Describes the method of producing scientific knowledge in the field of biology
PLO05 Bilgi - Kuramsal, Olgusal They will receive information on the biology area, in order to classify it uses and purposes.
PLO06 Bilgi - Kuramsal, Olgusal They use advanced theoretical and practical knowledge that obtain in biology field.
PLO07 Bilgi - Kuramsal, Olgusal They are Field-related issues can inform the relevant persons and institutions, They share ideas and problems relating to suggestions as the written, oral and Visual to expert or transfer to non-experts. 3
PLO08 Bilgi - Kuramsal, Olgusal They can take responsibility as individuals and team members to solve unpredictable problems encountered in applications related to the field.
PLO09 Bilgi - Kuramsal, Olgusal they can take an active role as a member of the execution team the planning of projects related to the field.
PLO10 Beceriler - Bilişsel, Uygulamalı They know that life-long learning process and act accordingly. 4
PLO11 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği They will increase the knowledge and experience outside major issues with specific elective courses in different fields of biology.
PLO12 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği They speak English enough to communicate with colleagues to understand the basic concepts of biology.
PLO13 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği They both with colleagues, as well as areas with non-person establishes ethical uses of information and communication technology. In addition to professional development, in line with the interests and abilities of scientific, social, constantly improves itself by identifying learning needs in cultural and artistic fields. 4
PLO14 Yetkinlikler - Öğrenme Yetkinliği They assesses developments in biology versatile using scientific methods and techniques 3
PLO15 Yetkinlikler - Öğrenme Yetkinliği They know the importance of personal development and enforces the need.


Week Plan

Week Topic Preparation Methods
1 Introduction to toxicology Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Tartışma
2 Absorption, distribution, metabolism, side of action and excretion Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap
3 Phase I metabolism and pharmacogenetic Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma, Grup Çalışması
4 Conjugation and elimination of toxic substances Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
5 Physiological factors affecting xenobiotic metabolism Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
6 Adaptation Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
7 Cell injury and cellular protection mechanism Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
8 Mid-Term Exam Review of the relevant pages from sources Ölçme Yöntemleri:
Yazılı Sınav, Proje / Tasarım, Performans Değerlendirmesi
9 Reactive metabolites and toxicity Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
10 Central nervous system and toxicity Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
11 Neurodegenerative disease neurotoxicity mechanisms Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma, Grup Çalışması
12 Hepatotoxicity Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma, Grup Çalışması
13 Nutritional Factors Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma, Grup Çalışması
14 Toxic effects of global warming Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma, Proje Temelli Öğrenme
15 Molecular techniques in toxicology Review of the relevant pages from sources Öğretim Yöntemleri:
Anlatım
16 Term Exams Ölçme Yöntemleri:
Performans Değerlendirmesi, Proje / Tasarım, Yazılı Sınav
17 Term Exams Ölçme Yöntemleri:
Yazılı Sınav, Performans Değerlendirmesi


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 2 28
Out of Class Study (Preliminary Work, Practice) 14 2 28
Assesment Related Works
Homeworks, Projects, Others 1 0 0
Mid-term Exams (Written, Oral, etc.) 1 8 8
Final Exam 1 24 24
Total Workload (Hour) 88
Total Workload / 25 (h) 3,52
ECTS 4 ECTS

Update Time: 30.05.2024 11:07