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Information
| Code | SHS159 |
| Name | Toxicology |
| Term | 2024-2025 Academic Year |
| Semester | 1. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Ön Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Mustafa TUNÇSOY |
| Course Instructor |
Mustafa TUNÇSOY
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
The aim of this course is to provide an overview of the field of toxicology, which covers the basic principles of toxicology, the toxic action mechanisms of xenobiotics, target organ toxicity, explanation of cell damage and protection mechanisms, toxicity of the compound group and risk assessment.
Course Content
The content of this course consists of the basic principles of toxicology, factors affecting toxicity, entry routes of toxins, absorption, distribution and excretion, biotransformation of toxic chemicals, toxic effects mechanisms of xenobiotics, application areas of toxicology, risk assessment, environmental toxicology, nanotoxicology and cell damage and protection mechanisms.
Course Precondition
None
Resources
Toxicology Lecture Notes
Notes
Powerpoint presentation
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Understands the basic principles of toxicology |
| LO02 | Describes how different chemicals enter, process, and are eliminated from the body. |
| LO03 | Knows the application areas of toxicology. |
| LO04 | Comprehends the entry routes, absorption, distribution and excretion of toxins and toxic effects mechanisms. |
| LO05 | Explain the toxic action mechanisms and biotransformation of xenobiotics. |
| LO06 | Knows cell damage and protection mechanisms, reactive metabolites and toxicity in various tissues, organs and systems. |
| LO07 | Knows the concepts of Environmental Toxicology, Nanotoxicology and Nanoecotoxicology. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explains the basis of human normal structure and function | 5 |
| PLO02 | Bilgi - Kuramsal, Olgusal | List the basic characteristics of diseases | 5 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the basic information about characteristics of microorganisms and parasites and the diseases that they cause. | 5 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Defines disinfection, sterilization and hygiene. | 4 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Recognizes laboratory tools and materials, lists measurement methods. | 2 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Implements the procedures to be carried out at preanalytical, analytical and postanalytical phases of the measurements by using detailed information of these stages. | |
| PLO07 | Bilgi - Kuramsal, Olgusal | Receives and accepts biological materials taken from the patient in accordance with the procedure, prepares them for analysis, and ensures that they are preserved under appropriate conditions if necessary. | 2 |
| PLO08 | Bilgi - Kuramsal, Olgusal | Performs the internal and external quality control studies of the analyses and the analyses of patient samples after applying the daily control procedures. | |
| PLO09 | Bilgi - Kuramsal, Olgusal | Checks the material analysis results and reports them to the laboratory specialist. | |
| PLO10 | Bilgi - Kuramsal, Olgusal | Performs the calibration and maintenance of laboratory equipments, have them to be calibrated and maintained and monitored by authorized persons as needed, so that they work most efficiently | |
| PLO11 | Bilgi - Kuramsal, Olgusal | Determines inaduquaciesis in the laboratory | |
| PLO12 | Bilgi - Kuramsal, Olgusal | Knows the critical values and provides coordination by reporting the results to the clinician in the most appropriate and fast manner. | 4 |
| PLO13 | Beceriler - Bilişsel, Uygulamalı | Develops himself and his career by critically evaluating the information he has learned with his own knowledge after graduation. | 5 |
| PLO14 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Having professional and ethical responsibility, they communicate well with colleagues, patients and physicians. | 5 |
| PLO15 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Uses at least one foreign language to follow developments in his field and to communicate with colleagues adequately. | |
| PLO16 | Yetkinlikler - Öğrenme Yetkinliği | Takes measures regarding health, biosafety and occupational safety in the work environment. | 1 |
| PLO17 | Yetkinlikler - Öğrenme Yetkinliği | He/She directs his career with the knowledge he has gained by following the professional and technological developments. | 5 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to toxicology | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 2 | Fundamentals of toxicology: factors affecting toxicity | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 3 | Application areas of toxicology | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 4 | Entry routes, absorption, distribution and excretion of toxins | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 5 | Mechanisms of toxic effects | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 6 | Toxic action mechanisms of xenobiotics | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 7 | Biotransformation of toxic chemicals | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav |
|
| 9 | Cell damage and protection mechanisms | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 10 | Reactive metabolites and toxicity | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 11 | Nervous system and toxicity | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 12 | Hepatotoxicity and liver damage | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 13 | Respiratory and Circulatory system and toxicity | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 14 | Environmental Toxicology | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 15 | Nanotoxicology | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 16 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 78 | ||
| Total Workload / 25 (h) | 3,12 | ||
| ECTS | 3 ECTS | ||