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Information
| Code | SHS159 |
| Name | Toxicology |
| Term | 2024-2025 Academic Year |
| Semester | 1. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Ön Lisans Dersi |
| Type | Normal |
| Label | VK Vocational Knowledge Courses E Elective |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi Mustafa TUNÇSOY |
| Course Instructor |
Dr. Öğr. Üyesi Mustafa TUNÇSOY
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
The aim of this course is to provide an overview of the field of toxicology, which covers the basic principles of toxicology, the toxic action mechanisms of xenobiotics, target organ toxicity, explanation of cell damage and protection mechanisms, toxicity of the compound group and risk assessment.
Course Content
The content of this course consists of the basic principles of toxicology, factors affecting toxicity, entry routes of toxins, absorption, distribution and excretion, biotransformation of toxic chemicals, toxic effects mechanisms of xenobiotics, application areas of toxicology, risk assessment, environmental toxicology, nanotoxicology and cell damage and protection mechanisms.
Course Precondition
None
Resources
Toxicology Lecture Notes
Notes
Powerpoint presentation
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Understands the basic principles of toxicology |
| LO02 | Describes how different chemicals enter, process, and are eliminated from the body. |
| LO03 | Explain the application areas of toxicology. |
| LO04 | Comprehends the entry routes, absorption, distribution and excretion of toxins and toxic effects mechanisms. |
| LO05 | Explain the toxic action mechanisms and biotransformation of xenobiotics. |
| LO06 | Understands cell damage and protection mechanisms, reactive metabolites and toxicity in various tissues, organs and systems. |
| LO07 | Explain the concepts of Environmental Toxicology, Nanotoxicology and Nanoecotoxicology. |
| LO08 | Understands the toxicity of nanoparticles |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explains the basis of human normal structure and function | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Defines disinfection, sterilization and hygiene. | 4 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Recognizes laboratory tools and materials, lists measurement methods. | 2 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Explains the procedures to be performed in these phases using detailed information on the preanalytical, analytical and postanalytical phases of measurements. | |
| PLO05 | Bilgi - Kuramsal, Olgusal | Receives and accepts biological materials taken from the patient, prepares them for analysis and ensures that they are preserved under appropriate conditions if necessary. | 2 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Performs internal and external quality control studies of the analyzes, analyzes patient samples after applying daily control procedures, checks the results and reports to the laboratory specialist. | |
| PLO07 | Bilgi - Kuramsal, Olgusal | Performs the calibration and maintenance of laboratory equipments, have them to be calibrated and maintained and monitored by authorized persons as needed, so that they work most efficiently | |
| PLO08 | Bilgi - Kuramsal, Olgusal | Determines inaduquaciesis in the laboratory | |
| PLO09 | Bilgi - Kuramsal, Olgusal | Knows the critical values and provides coordination by reporting the results to the clinician in the most appropriate and fast manner. | 4 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | After graduation, he/she develops himself/herself and his/her career by following technological developments and critically evaluating the information he/she has learned with his/her own knowledge. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Having professional and ethical responsibility, they communicate well with colleagues, patients and physicians. | |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Uses at least one foreign language to follow developments in his field and to communicate with colleagues adequately. | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Takes measures regarding health, biosafety and occupational safety in the work environment. | 1 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to toxicology | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 2 | Fundamentals of toxicology: factors affecting toxicity | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 3 | Application areas of toxicology | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 4 | Entry routes, absorption, distribution and excretion of toxins | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 5 | Mechanisms of toxic effects | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 6 | Toxic action mechanisms of xenobiotics | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 7 | Biotransformation of toxic chemicals | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav |
|
| 9 | Cell damage and protection mechanisms | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 10 | Reactive metabolites and toxicity | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 11 | Nervous system and toxicity | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 12 | Hepatotoxicity and liver damage | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 13 | Respiratory and Circulatory system and toxicity | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 14 | Environmental Toxicology | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 15 | Nanotoxicology | Browse and read different course resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 16 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
|
| 17 | Term Exams | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 78 | ||
| Total Workload / 25 (h) | 3,12 | ||
| ECTS | 3 ECTS | ||