TÜRKÇE
ENGLISH
Information
| Code | VTS319 |
| Name | Stem Cells and Cellular Therapies in Veterinary Medicine |
| Term | 2024-2025 Academic Year |
| Semester | 5. Semester |
| Duration (T+A) | 1-0 (T-A) (17 Week) |
| ECTS | 1 ECTS |
| National Credit | 1 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Label | FE Field Education Courses E Elective |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Dr. Öğr. Üyesi SİNAN KANDIR |
| Course Instructor |
Dr. Öğr. Üyesi SİNAN KANDIR
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
This course covers the topics on concepts and types of stem cells, isolation and clinical applications, knowledge on basic level for genetic modification options for gene therapy are presented.
Course Content
To educate professionally conscious veterinarians on stem cells and their types, isolations and clinical applications, gene therapy options, protocols and their ethical debates and legal regulations.
Course Precondition
None
Resources
Lecture Nores (Kandır S., 2022)
Notes
Related literature, lecture notes, presentations and video images related to the subject.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | The student has knowledge about stem cells, types and isolation. |
| LO02 | The student has an idea about the isolation and characterization of the stem cells by the usage of advanced techniques |
| LO03 | To be able to know and discuss ethical and legal regulations about stem cell therapy and its therapeutic use |
| LO04 | The student has a knowledge of the gene cloning toolkits which are necessary for gene therapy protocols. |
| LO05 | The studfent gain vocational vision and skills for clinical use of gene therapy. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Distinguishes animal species and breeds based on their structural (morphological), functional (physiological, biochemical) and behavioral characteristics and whether they can be consumed for food purposes. | 2 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Explains the sources, physical and chemical properties and preparation of drugs. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Describes the effects and side effects of medications on patients | 4 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Explains the formation mechanisms of animal diseases and their pathological effects on the body. | 5 |
| PLO05 | Bilgi - Kuramsal, Olgusal | It makes efficiency evaluations among animal breeds and, when necessary, carries out selection, hybridization and artificial insemination at a level that can carry out breeding work. | |
| PLO06 | Bilgi - Kuramsal, Olgusal | Disposes of dead animal material, tissue samples, medical and chemical waste appropriately in accordance with international, national laws and regulations. | 2 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | It determines the correct approach area for the patient by evaluating the examination, operation etc. practices in the clinic according to the topographic anatomy. | 3 |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Uses biochemical parameters in diagnostic processes by evaluating the information obtained with cause-effect relationships. | |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Writes prescriptions in accordance with diagnosis and treatment protocols for diseases and poisoning in animals. | 3 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Implements necessary measures, including biosecurity, to control infectious diseases. | 4 |
| PLO11 | Beceriler - Bilişsel, Uygulamalı | Performs necropsy to evaluate findings in dead animals, directs tissues to the necessary laboratory according to appropriate storage methods and prepares a report. | 4 |
| PLO12 | Beceriler - Bilişsel, Uygulamalı | Monitors patients in the post-operative process according to the main treatment methods of surgical diseases in animal species. | 4 |
| PLO13 | Beceriler - Bilişsel, Uygulamalı | Applies sedation, anesthesia and pain management methods safely according to animal species. | |
| PLO14 | Beceriler - Bilişsel, Uygulamalı | Correctly applies biosafety principles such as sterilization of clinical and laboratory equipment and clothing. | 3 |
| PLO15 | Beceriler - Bilişsel, Uygulamalı | It regulates the care and feeding protocols according to animal species and supervises the consumption of animal foods produced for human consumption or foods containing animal products in their composition. | |
| PLO16 | Beceriler - Bilişsel, Uygulamalı | Evaluates laboratory results of animal diseases and applies correct diagnosis, prognosis and treatment methods based on the data obtained. | |
| PLO17 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | He/she is conscious of performing his/her profession by being aware of his/her powers and responsibilities. | |
| PLO18 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Examines scientific techniques and methods according to facts related to veterinary services and takes analysis or methodological responsibility for problems. | |
| PLO19 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | It uses adequate technology in the hygienic production, manufacturing, processing, consumption and sales of food by conducting health control of animal food products produced for human consumption. | |
| PLO20 | Yetkinlikler - Öğrenme Yetkinliği | Lists the methods of producing and using scientific knowledge in his/her professional field. | |
| PLO21 | Yetkinlikler - Öğrenme Yetkinliği | Uses updated legislation regarding veterinary services when necessary. | 2 |
| PLO22 | Yetkinlikler - Öğrenme Yetkinliği | Performs an examination appropriate to the case, applying the contribution of imaging methods to diagnosis and radiation safety in accordance with current regulations. | |
| PLO23 | Yetkinlikler - Öğrenme Yetkinliği | Keeps clinical and patient records using proper and scientific methods. | |
| PLO24 | Yetkinlikler - Öğrenme Yetkinliği | By observing the basic principles of medicine, it develops management methods and appropriate management plans for animal production enterprises. | |
| PLO25 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Implement social projects and plans with social awareness, based on professional skills and authority with a computer usage license, advanced computer software. | |
| PLO26 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Works in cooperation with other colleagues by following the world agenda within the framework of professional ethics and deontology rules. | |
| PLO27 | Yetkinlikler - Alana Özgü Yetkinlik | Produces solutions to field-specific problems in line with scientific data/evidence. | |
| PLO28 | Yetkinlikler - Alana Özgü Yetkinlik | He/she has the ethical values of the veterinary profession and defends these values. | |
| PLO29 | Yetkinlikler - Alana Özgü Yetkinlik | Takes appropriate precautions by clinically recognizing zoonosis and notifiable diseases. | |
| PLO30 | Yetkinlikler - Alana Özgü Yetkinlik | Determines the methods of diagnosis, prevention, treatment and operation of diseases in different animal species. | |
| PLO31 | Yetkinlikler - Alana Özgü Yetkinlik | In emergency cases, intervenes in all animals and applies first aid methods. | |
| PLO32 | Yetkinlikler - Alana Özgü Yetkinlik | Makes judgments on animal husbandry principles and breeding by assessing the physical condition, welfare and rearing conditions of domestic animals, communicating appropriately with animal owners and colleagues. | |
| PLO33 | Yetkinlikler - Alana Özgü Yetkinlik | Independently interprets articles and presentations published in other scientific fields related to Veterinary Medicine to maintain professional development and skills. | |
| PLO34 | Yetkinlikler - Alana Özgü Yetkinlik | When necessary, euthanizes animals using appropriate methods and respecting the feelings of animal owners. | |
| PLO35 | Yetkinlikler - Alana Özgü Yetkinlik | By mastering the concepts of occupational safety in terms of the workplace and the personnel working with it, they have the competence to apply and defend it. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Stem cell - Scope and targets, types of stem cells, classification of stem cells according to pluripotent potentials | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Grup Çalışması, Beyin Fırtınası, Altı Şapka, Örnek Olay, Bireysel Çalışma, Problem Çözme |
| 2 | Embryonic stem cell - Identification and use of embryonic stem cells | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Grup Çalışması, Beyin Fırtınası, Altı Şapka, Örnek Olay, Deney / Laboratuvar, Bireysel Çalışma, Problem Çözme |
| 3 | Regulation of stem cell function, hematopoietic stem cell identification and usage areas | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Grup Çalışması, Beyin Fırtınası, Altı Şapka, Örnek Olay, Bireysel Çalışma, Problem Çözme |
| 4 | Molecular targets used for mesenchymal stem cell characterization and their uses | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası, Altı Şapka, Örnek Olay, Bireysel Çalışma, Problem Çözme |
| 5 | Cell culture basics | Related books and articles | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama, Deney / Laboratuvar |
| 6 | Stem cell isolation and clinical applications | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Grup Çalışması, Altı Şapka, Örnek Olay, Deney / Laboratuvar, Bireysel Çalışma, Problem Çözme |
| 7 | Ethical and legal regulations, limitations for stem cell applications and gene therapy | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Grup Çalışması, Altı Şapka, Örnek Olay, Deney / Laboratuvar, Problem Çözme, Proje Temelli Öğrenme |
| 8 | Mid-Term Exam | Related books and articles | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav, Ödev, Proje / Tasarım, Performans Değerlendirmesi |
| 9 | Gene Engineering and Recombinant DNA technology | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Grup Çalışması, Beyin Fırtınası, Altı Şapka, Örnek Olay, Deney / Laboratuvar, Problem Çözme, Proje Temelli Öğrenme |
| 10 | Vectors for gene cloning; plasmids and bacteriophages | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası, Altı Şapka, Örnek Olay, Deney / Laboratuvar, Bireysel Çalışma, Problem Çözme, Proje Temelli Öğrenme |
| 11 | Gene cloning; examine genetic locality, structure, expression level | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Grup Çalışması, Beyin Fırtınası, Altı Şapka, Örnek Olay, Deney / Laboratuvar, Bireysel Çalışma, Problem Çözme, Proje Temelli Öğrenme |
| 12 | Transcriptomics and proteomics analysis | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası, Altı Şapka, Örnek Olay, Deney / Laboratuvar, Bireysel Çalışma, Problem Çözme, Proje Temelli Öğrenme |
| 13 | Genetic diseases and current gene therapy options in pets | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası, Altı Şapka, Örnek Olay, Deney / Laboratuvar, Bireysel Çalışma, Problem Çözme, Proje Temelli Öğrenme |
| 14 | Genetic diseases and current gene therapy options in farm animals | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Grup Çalışması, Beyin Fırtınası, Altı Şapka, Örnek Olay, Deney / Laboratuvar, Bireysel Çalışma, Problem Çözme, Proje Temelli Öğrenme |
| 15 | Bioreactors and transgenic animal technology | Related books and articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Alıştırma ve Uygulama, Grup Çalışması, Beyin Fırtınası, Altı Şapka, Örnek Olay, Deney / Laboratuvar, Bireysel Çalışma, Problem Çözme, Proje Temelli Öğrenme |
| 16 | Term Exams | Related books and articles | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav, Ödev, Performans Değerlendirmesi |
| 17 | Term Exams | Related books and articles | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav, Ödev, Proje / Tasarım, Portfolyo, Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 1 | 14 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 1 | 14 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 2 | 2 |
| Final Exam | 1 | 4 | 4 |
| Total Workload (Hour) | 34 | ||
| Total Workload / 25 (h) | 1,36 | ||
| ECTS | 1 ECTS | ||