BMM0086 Biochemical Calculations

6 ECTS - 3-0 Duration (T+A)- . Semester- 3 National Credit

Information

Code BMM0086
Name Biochemical Calculations
Term 2024-2025 Academic Year
Term Spring
Duration (T+A) 3-0 (T-A) (17 Week)
ECTS 6 ECTS
National Credit 3 National Credit
Teaching Language Türkçe
Level Yüksek Lisans Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator
Course Instructor
1


Course Goal / Objective

The aim of this course is to understand the properties and behavior of biological molecules using basic mathematics.

Course Content

Solutions of numerical problems in biochemistry involving acid-base chemistry, blood buffers, chemistry of biological molecules, enzymes, biochemical energetics, spectrophotometry.

Course Precondition

None

Resources

Lawrence A. Kaplan, Amadeo J. Pesce Teory Analysis Correlations Clinical Chemistry. Mosby ELSEVIER, Indiana, 2010.

Notes

Carl A. Burtis, Edward R. Ashwood. Tietz Klinik kimyada temel ilkeler. Çeviri editörü Prof Dr Diler Aslan Palme yayıncılık, Ankara, 2005. 2. K. Moorthy, Fundamentals of Biochemical Calculations. 2nd Edn. CRC Press, Taylor & Francis Group, Boca Raton, FL. 2008.


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Understands the properties of solutions.
LO02 Learns the dissolution phenomenon and the factors affecting solubility.
LO03 Have information about concentration units.
LO04 Understands the calculation of ion concentrations in solution by understanding the equilibrium constant.


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal To be able to solve scientific problems encountered in the field of medicine and medical technologies by applying current and advanced technical approaches of mathematics, science and engineering sciences. 3
PLO02 Yetkinlikler - Öğrenme Yetkinliği To have a knowledge of the literature related to a sub-discipline of biomedical engineering, to define and model current problems. 4
PLO03 Beceriler - Bilişsel, Uygulamalı Ability to analyze data, design and conduct experiments, and interpret results 4
PLO04 Beceriler - Bilişsel, Uygulamalı Developing researched contemporary techniques and computational tools for engineering applications
PLO05 Beceriler - Bilişsel, Uygulamalı To be able to analyze and design a process in line with a defined target 4
PLO06 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Conducting scientific studies with a medical doctor from an engineering perspective. 4
PLO07 Yetkinlikler - İletişim ve Sosyal Yetkinlik Expressing own findings orally and in writing, clearly and concisely.
PLO08 Yetkinlikler - Öğrenme Yetkinliği To be able to improve oneself by embracing the importance of lifelong learning and by following the developments in science-technology and contemporary issues.
PLO09 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Ability to act independently, set priorities and creativity. 3
PLO10 Yetkinlikler - Alana Özgü Yetkinlik Being aware of national and international contemporary scientific and social problems in the field of Biomedical Engineering.
PLO11 Yetkinlikler - Alana Özgü Yetkinlik To be able to evaluate the contribution of engineering solutions to problems in medicine, medical technologies and health in a global and social context. 5


Week Plan

Week Topic Preparation Methods
1 Dissolution-Resolution: Dissolution of ionic and covalent (polar-nonpolar) particules Read about the subject Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
2 Factors affecting the resolution; temperature, pressure, solvent type. Exothermic and endothermic dissolution. Read about the subject Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
3 Concentration Units1: % concentrations and osmolarity Molarite-osmolality, molality-osmolality; isotonic, hypotonic and hypertonic solutions. Read about the subject. Öğretim Yöntemleri:
Soru-Cevap, Anlatım, Grup Çalışması
4 Concentration Units 2: Normality, equivalent grams and ionic strength calculations Read about the subject. Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
5 Chemical reactions and equilibrium, equilibrium of constant and rates of reaction Read about the subject. Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
6 Acids and Bases: Definition of Acid-base, strong and weak acids and bases; chemical properties of the acid and base Read about the subject. Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
7 Buffers Read about the subject. Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
8 Mid-Term Exam Subject repetition and explanation Ölçme Yöntemleri:
Yazılı Sınav, Ödev
9 Dilutions Read about the subject. Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
10 Ionization of water: Kd and Ks of Water, calculation of H+ and OH- ion concentration of water Read about the subject. Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
11 The calculation of H + and OH- concentration in strong and weak acid-base , degree of ionization. Read about the subject. Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
12 pH and pOH: pH and pOH value of water; pH scale (criteria), calculation of pH and pOH related to strong-weak acid and base Read about the subject. Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
13 Neutralization Reactions: pH and pOH calculations in acid-base mixture, titration curves Read about the subject. Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
14 Amino acids of the ionization, calculations of isoelectric spot Read about the subject. Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
15 Hydrolysis and salts: the relationship between Ka and Kb constants for weak acids and bases Read about the subject. Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Grup Çalışması
16 Term Exams Subject repetition and explanation Ölçme Yöntemleri:
Yazılı Sınav, Ödev
17 Term Exams Subject repetition and explanation Ölçme Yöntemleri:
Yazılı Sınav


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 3 42
Out of Class Study (Preliminary Work, Practice) 14 5 70
Assesment Related Works
Homeworks, Projects, Others 5 5 25
Mid-term Exams (Written, Oral, etc.) 1 2 2
Final Exam 1 2 2
Total Workload (Hour) 141
Total Workload / 25 (h) 5,64
ECTS 6 ECTS

Update Time: 19.05.2024 10:46