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Information
| Unit | INSTITUTE OF NATURAL AND APPLIED SCIENCES |
| BIOTECHNOLOGY (MASTER) (WITH THESIS) (INTERDISCIPLINARY) | |
| Code | BT050 |
| Name | Enzyme Immobilization and Immobilized Enzymes |
| Term | 2024-2025 Academic Year |
| Term | Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. DENİZ YILDIRIM |
| Course Instructor |
Prof. Dr. DENİZ YILDIRIM
(Bahar)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
The aim of this course is to teach the principles of enzyme immobilization and basic principles of enzyme immobilization methods and to develop a theoretical background about immobilized enzymes.
Course Content
Overview of Enzyme Immobilization, Enzyme Immobilization Methods, Covalent Immobilization, Adsorption-Based Methods, Encapsulation Methods, Cross-linked Enzyme Aggregates, Characterization of Immobilized Enzymes, Industrial Uses of Immobilized Enzymes
Course Precondition
None
Resources
Jose M. Guisan, Immobilization of Enzymes and Cells, Third Edition
Notes
Lecture notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Define protein structure. |
| LO02 | Explain biocatalysis term. |
| LO03 | List enzyme classes. |
| LO04 | Define specific activity. |
| LO05 | Explain enzyme immobilization and its principles. |
| LO06 | List the enzyme immobilization methods. |
| LO07 | Explain the importance of characterizing immobilized enzymes. |
| LO08 | List the industrial uses of immobilized enzymes. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on undergraduate level qualifications, they develop their knowledge at the level of expertise in the same or a different field. | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Knows the ethical rules to be considered while obtaining biotechnological products. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | To identifiy the interdisciplinary interaction of the field and to solve use of the methods. | 3 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Interpret the knowledge gained in the field by integrating the information from different disciplines and creates new information | |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Develops new strategic approaches for solving complex problems that are encountered in applications related to the field. | |
| PLO06 | Yetkinlikler - Öğrenme Yetkinliği | To teach the social, scientific, cultural and ethical values during the collection, interpretation, implementation and announcement of the data related to the field. | |
| PLO07 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | To solve the problems encountered in the field and cominicate by using research methods. | 4 |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Establishes functional interaction by using strategic decision-making processes in solving the problems encountered in the field. | |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. | 3 |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | To gain the ability to develop and deepen the knowledge in the field of biotechnology |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Overview of Enzyme Immobilization | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım |
| 2 | Enzyme Immobilization Methods | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım, Tartışma |
| 3 | Covalent Enzyme Immobilization-Introduction | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım, Tartışma |
| 4 | Covalent Enzyme Immobilization | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 5 | Adsorption-Based Immobilization Methods-Introduction | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım, Tartışma |
| 6 | Adsorption-Based Immobilization Methods | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım |
| 7 | Ionic bonding methods | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Study related lecture notes | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Encapsulation Methods | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım, Tartışma |
| 10 | Cross-linked Enzyme Aggregates | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım |
| 11 | Cell immobilization | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | Characterization of Immobilized Enzymes-Introduction | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | Characterization of Immobilized Enzymes | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | Industrial Uses of Immobilized Enzymes-Introduction | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Industrial Uses of Immobilized Enzymes | Reading the subject from related textbooks, lecture notes and other sources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Study related lecture notes | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Study related lecture notes | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 5 | 70 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 15 | 15 |
| Final Exam | 1 | 30 | 30 |
| Total Workload (Hour) | 157 | ||
| Total Workload / 25 (h) | 6,28 | ||
| ECTS | 6 ECTS | ||