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Information
| Code | BT0110 |
| Name | Molecular Parasitology |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 4-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 4 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator |
Course Goal / Objective
The aim of this course is to ensure a better understanding of the diagnosis, treatment, and protection techniques against parasitic diseases by learning the molecular cell structures, metabolism, genetic and antigenic structures of the parasites.
Course Content
This course focuses on the cell and tissue structure, metabolism, genetic and antigenic properties of the parasites that lead to significant economic losses and deaths; the serological and molecular detection of the diseases caused by these parasites as well as the vaccine studies for these diseases.
Course Precondition
NONE
Resources
To have knowlegde about general parasitology and molecular biology
Notes
Bowman DD. Georgis Parasitology for Veterinarians.10th ed. Elseiver; 2014. p. 326-398.Taylor MA, Coop RL, Wall RL, Veterinary Parasitology. 4th ed. Wiley Blackwell; 2016. Zajac AM, Conboy GA, Veterinary Clinical Parasitology. 8th ed. John Wiley and Sons, Inc; 2012. Freeman S, Herron JC, Evrimsel Analiz. Çıplak, B, Başıbüyük H, Karaytuğ, S, Gündüz, İ. (eds). Palme Yayıncılık, Ankara, 2009. Lemey P, Salemi M, Vandamme AM, The Phylogenetic Handbook, A Practical Approach to Phylogenetic Analysis and Hypothesis Testing, Cambridge University Press, 2009. Pevsner J, Bioinformatics and Functional Genomics, Wiley-Blackwell, 2009. Xıong J, Essential Bioinformatics, Cambridge University Press, 2006.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Students learn the cell structures of the parasites and parasite metabolism. |
| LO02 | Students know the genetic and antigenic properties of parasites. |
| LO03 | Students learn the basic parasitological terms, naming of parasites, host-parasite relationships, and parasitism types. |
| LO04 | Students learn the development and the proliferation of parasites, transmission paths and general clinical symptoms they form. |
| LO05 | Students learn the collection and conservation of parasites and DNA extraction from parasitic tissues. |
| LO06 | Students have knowledge about the serological tests (ELISA, IFAT, CFT, SFDT etc.) used in parasitology. |
| LO07 | Students learn the molecular tests (PCR, RT-PCR,DNA sequencing, RAPD-PCR, PCR-RFLP) used in parasitology. |
| LO08 | Students learn the anti-parasitic vaccines. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develop and deepen the current and advanced knowledge in the field with original thought and / or research at the level of expertise based on the qualifications of the graduate and reach the original definitions that will bring innovation to the field. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Understands the interdisciplinary interaction of the field; it achieves original results using knowledge requiring expertise in analysis, synthesis and evaluation of new and complex ideas. | 4 |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Evaluates, uses and transfers new information in the field with a systematic approach. | 3 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Makes critical analysis, synthesis and evaluation of new and complex thoughts. | 3 |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Makes leadership in environments that require the analysis of original and interdisciplinary problems. | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | It extends the limits of knowledge in its field by publishing at least one scientific article in its field in national and / or international refereed journals and / or producing or interpreting an original work. | 2 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. | 2 |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. | 3 |
| PLO09 | Yetkinlikler - Alana Özgü Yetkinlik | Conducts scientific research in national and international scientific research groups. | 2 |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | Establishes functional interaction by using strategic decision making processes in solving problems encountered in the field. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Basic parasitological terms, naming of parasites, host-parasite relations, and types of parasitism | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Gösterip Yaptırma, Soru-Cevap |
| 2 | Cell structure and the metabolism of parasites | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Genome organisation in parasites, eucaryotic genes, structure of DNA, DNA replication | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Tartışma, Gösterip Yaptırma |
| 4 | Transcription, translation, and gene regulation | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | General immunology | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Parasite immunology | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Antiparasitic vaccines | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Mid-Term Exam | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 9 | Clinical symptoms that induced by parasites in mammals | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Conventional diagnostic techniques in parasitology | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 11 | Serological diagnostic techniques (ELISA, IFAT, CFT, SFDT) in parasitology | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Molecular marker selection for the diagnosis of parasitic diseases | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Molecular diagnostic techniques (PCR, RT-PCR, DNA sequencing) in parasitology | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Molecular techniques (PCR, RT-PCR, PCR-RFLP, RAPD-PCR, SSCP, DNA sequencing) for the genotyping of parasitic agents | Lecture notes,slide projection | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Bireysel Çalışma |
| 15 | Term exams | Term exams | Ölçme Yöntemleri: Sözlü Sınav, Ödev |
| 16 | Term Exams | Term Exams | Ölçme Yöntemleri: Sözlü Sınav, Ödev |
| 17 | Term Exams | Term Exams | Ölçme Yöntemleri: Ödev, Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 28 | 28 |
| Total Workload (Hour) | 152 | ||
| Total Workload / 25 (h) | 6,08 | ||
| ECTS | 6 ECTS | ||