TÜRKÇE
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Information
| Code | BT0110 |
| Name | Molecular Parasitology |
| Term | 2024-2025 Academic Year |
| Term | Spring |
| Duration (T+A) | 4-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 4 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
Prof. Dr. ARMAĞAN ERDEM ÜTÜK
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
The aim of this course is to ensure a better understanding of the diagnosis, treatment, and protection techniques against parasitic diseases by learning the molecular cell structures, metabolism, genetic and antigenic structures of the parasites.
Course Content
This course focuses on the cell and tissue structure, metabolism, genetic and antigenic properties of the parasites that lead to significant economic losses and deaths; the serological and molecular detection of the diseases caused by these parasites as well as the vaccine studies for these diseases.
Course Precondition
NONE
Resources
To have knowlegde about general parasitology and molecular biology
Notes
1. Bowman DD. Georgis Parasitology for Veterinarians.10th ed. Elseiver; 2014. p. 326-398. 2. Taylor MA, Coop RL, Wall RL, Veterinary Parasitology. 4th ed. Wiley Blackwell; 2016. 3. Zajac AM, Conboy GA, Veterinary Clinical Parasitology. 8th ed. John Wiley and Sons, Inc; 2012. 4. Freeman S, Herron JC, Evrimsel Analiz. Çıplak, B, Başıbüyük H, Karaytuğ, S, Gündüz, İ. (eds). Palme Yayıncılık, Ankara, 2009. 5. Lemey P, Salemi M, Vandamme AM, The Phylogenetic Handbook, A Practical Approach to Phylogenetic Analysis and Hypothesis Testing, Cambridge University Press, 2009. 6. Pevsner J, Bioinformatics and Functional Genomics, Wiley-Blackwell, 2009. Xıong J, Essential Bioinformatics, Cambridge University Press, 2006.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explains the cell structures of the parasites and parasite metabolism. |
| LO02 | Interprets the genetic and antigenic characteristics of parasites. |
| LO03 | Explains the basic parasitological terms, naming of parasites, host-parasite relationships, and parasitism types. |
| LO04 | Interprets the development patterns, reproduction, transmission routes, and general clinical symptoms of helminths, protozoa, and arthropods. |
| LO05 | Collects parasitic agents, preserves them, and performs DNA extraction |
| LO06 | Compares and interprets the similarities and differences of serological tests (ELISA, IFAT, CFT, SFDT, etc.) used in parasitology. |
| LO07 | Explain the molecular tests (PCR, RT-PCR,DNA sequencing, RAPD-PCR, PCR-RFLP) used in parasitology. |
| LO08 | List the anti-parasitic vaccines. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develop and deepen the current and advanced knowledge in the field with original thought and / or research at the level of expertise based on the qualifications of the graduate and reach the original definitions that will bring innovation to the field. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Understands the interdisciplinary interaction of the field; it achieves original results using knowledge requiring expertise in analysis, synthesis and evaluation of new and complex ideas. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Evaluates, uses and transfers new information in the field with a systematic approach. | |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Makes critical analysis, synthesis and evaluation of new and complex thoughts. | 3 |
| PLO05 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Makes leadership in environments that require the analysis of original and interdisciplinary problems. | |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | It extends the limits of knowledge in its field by publishing at least one scientific article in its field in national and / or international refereed journals and / or producing or interpreting an original work. | |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. | |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. | |
| PLO09 | Yetkinlikler - Alana Özgü Yetkinlik | Conducts scientific research in national and international scientific research groups. | 2 |
| PLO10 | Yetkinlikler - Alana Özgü Yetkinlik | Establishes functional interaction by using strategic decision making processes in solving problems encountered in the field. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Basic parasitological terms, naming of parasites, host-parasite relations, and types of parasitism | Conducting internet research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Cell structure and the metabolism of parasites | Conducting internet research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösteri |
| 3 | Genome organisation in parasites, eucaryotic genes, structure of DNA, DNA replication | Slide review | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösteri |
| 4 | Transcription, translation, and gene regulation | Slide review | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | General immunology | Slide review, Conducting internet research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Parasite immunology | Textbook reading, Slide review | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Antiparasitic vaccines | Textbook reading, Slide review | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Studying for an exam | Ölçme Yöntemleri: Ödev |
| 9 | Clinical symptoms that induced by parasites in mammals | Conducting internet research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası, Benzetim |
| 10 | Conventional diagnostic techniques in parasitology | Conducting internet research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Gösteri |
| 11 | Serological diagnostic techniques (ELISA, IFAT, CFT, SFDT) in parasitology | Slide review, Conducting internet research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösteri, Tartışma |
| 12 | Molecular marker selection for the diagnosis of parasitic diseases | Slide review, Conducting internet research | Öğretim Yöntemleri: Anlatım, Tartışma, Soru-Cevap, Gösteri |
| 13 | Molecular diagnostic techniques (PCR, RT-PCR, DNA sequencing) in parasitology | Slide review, Conducting internet research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Gösteri |
| 14 | Molecular techniques (PCR, RT-PCR, PCR-RFLP, RAPD-PCR, SSCP, DNA sequencing) for the genotyping of parasitic agents | Slide review, Conducting internet research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Gösteri |
| 15 | Basic Phylogenetic Concepts | Slide review, Conducting internet research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Studying for an exam | Ölçme Yöntemleri: Sözlü Sınav, Ödev |
| 17 | Term Exams | Studying for an exam | Ölçme Yöntemleri: Ödev, Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 6 | 84 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 4 | 4 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 1 | 1 |
| Final Exam | 1 | 1 | 1 |
| Total Workload (Hour) | 146 | ||
| Total Workload / 25 (h) | 5,84 | ||
| ECTS | 6 ECTS | ||