BT0152 Organic and Bioorganic Reaction Mechanisms

6 ECTS - 3-0 Duration (T+A)- . Semester- 3 National Credit

Information

Code BT0152
Name Organic and Bioorganic Reaction Mechanisms
Term 2024-2025 Academic Year
Semester . Semester
Duration (T+A) 3-0 (T-A) (17 Week)
ECTS 6 ECTS
National Credit 3 National Credit
Teaching Language Türkçe
Level Doktora Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator


Course Goal / Objective

Functional groups in organic and bioorganic structures and their structural properties, Some therapeutic molecules in molecular biology, Stereochemistry, Types of organic reactions; Biosynthesis, Nucleophilic Substitution Reactions, Elimination Reactions, Organic and Bioorganic Carbonyl Condensation Reactions, Esterification and Ester Hydrolysis Mechanism, Electrophilic Substitution Reactions, Organic and Bioorganic Synthesis Strategies, Frontier Orbital Theory, Pericyclic Reactions, Biosynthesis, Stereoselectivity in Organic and Bioorganic Synthesis Oxidation-reduction-electron transfer reactions, Biomolecules; amino acids, enzymes, proteins, nucleic acids, carbohydrates, oligoribonucleotides, ribophosphoramides and lipids. Organic Spectroscopy, Heterocyclic Compounds. Alkaloids, Asymmetric synthesis, Peptide synthesis and reaction mechanisms.

Course Content

Functional groups in organic and bioorganic structures and their structural properties, Some therapeutic molecules in molecular biology, Stereochemistry, Types of organic reactions; Biosynthesis, Nucleophilic Substitution Reactions, Elimination Reactions, Organic and Bioorganic Carbonyl Condensation Reactions, Esterification and Ester Hydrolysis Mechanism, Electrophilic Substitution Reactions, Organic and Bioorganic Synthesis Strategies, Frontier Orbital Theory, Pericyclic Reactions, Biosynthesis, Stereoselectivity in Organic and Bioorganic Synthesis Oxidation-reduction-electron transfer reactions, Biomolecules; amino acids, enzymes, proteins, nucleic acids, carbohydrates, oligoribonucleotides, ribophosphoramides and lipids. Organic Spectroscopy, Heterocyclic Compounds. Alkaloids, Asymmetric synthesis, Peptide synthesis and reaction mechanisms.

Course Precondition

None

Resources

KAYNAKLAR McMurry J., Organic Chemistry and Transparancy, Fifth Edition, Brooks/Cole, Thomson Learning, 2000. 2. Page, M.I., Williams, A.; Organic and Bio-Organic Mechanisms, Prentice Hall; 1st edition, 1997.

Notes

Lexcture note


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Recognizes functional groups in organic and bioorganic structures and knows the transformations of these groups.
LO02 Knows therapeutic molecules in molecular biology.
LO03 Learns and applies organic and bioorganic reaction mechanisms.
LO04 Gains knowledge and comments about organic and bioorganic synthesis strategies.
LO05 Knows the types of organic reactions and makes a synthesis plan for drug molecules.
LO06 Gains knowledge about drug and bioorganic molecules and develops synthesis strategies.


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Bilgi - Kuramsal, Olgusal Develop and deepen the current and advanced knowledge in the field with original thought and / or research at the level of expertise based on the qualifications of the graduate and reach the original definitions that will bring innovation to the field.
PLO02 Bilgi - Kuramsal, Olgusal Understands the interdisciplinary interaction of the field; it achieves original results using knowledge requiring expertise in analysis, synthesis and evaluation of new and complex ideas. 4
PLO03 Beceriler - Bilişsel, Uygulamalı Evaluates, uses and transfers new information in the field with a systematic approach. 5
PLO04 Beceriler - Bilişsel, Uygulamalı Makes critical analysis, synthesis and evaluation of new and complex thoughts.
PLO05 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Makes leadership in environments that require the analysis of original and interdisciplinary problems.
PLO06 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği It extends the limits of knowledge in its field by publishing at least one scientific article in its field in national and / or international refereed journals and / or producing or interpreting an original work.
PLO07 Yetkinlikler - Öğrenme Yetkinliği Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making.
PLO08 Yetkinlikler - İletişim ve Sosyal Yetkinlik He / she defends his / her original opinions in discussing the subjects in his / her field and establishes an effective communication showing his / her competence in the field. 3
PLO09 Yetkinlikler - Alana Özgü Yetkinlik Conducts scientific research in national and international scientific research groups. 4
PLO10 Yetkinlikler - Alana Özgü Yetkinlik Establishes functional interaction by using strategic decision making processes in solving problems encountered in the field.


Week Plan

Week Topic Preparation Methods
1 Functional groups in organic and bioorganic structures and their properties Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
2 Some therapeutic molecules used in molecular biology Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
3 Stereochemistry Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
4 Types of organic reactions and biosyntheses Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
5 Nucleophilic substitution and elimination reactions Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
6 Carbonyl condensation reactions Books and scientific database Öğretim Yöntemleri:
Soru-Cevap, Anlatım, Tartışma
7 Esterification and ester hydrolysis mechanism, Electrophilic substitution reactions Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
8 Mid-Term Exam Ölçme Yöntemleri:
Yazılı Sınav
9 Organic and bioorganic synthesis strategies Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
10 Frontier orbital theory, Pericyclic and Asymmetric synthesis reactions Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
11 Stereoselectivity in syntheses in Organic and Biosyntheses Books and scientific database Öğretim Yöntemleri:
Soru-Cevap, Anlatım, Tartışma
12 Oxidation-reduction-electron transfer reactions Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
13 Biomolecules; amino acids, enzymes, proteins and peptide syntheses Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
14 Nucleic acids, carbohydrates, oligo ribonucleotides, ribophosphoramides, lipids. Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
15 Organic Spectroscopy, Heterocyclic Compounds. Alkaloids and reaction mechanisms Books and scientific database Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma
16 Term Exams Ölçme Yöntemleri:
Yazılı Sınav
17 Term Exams Ölçme Yöntemleri:
Yazılı Sınav


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 3 42
Out of Class Study (Preliminary Work, Practice) 14 5 70
Assesment Related Works
Homeworks, Projects, Others 0 0 0
Mid-term Exams (Written, Oral, etc.) 1 15 15
Final Exam 1 30 30
Total Workload (Hour) 157
Total Workload / 25 (h) 6,28
ECTS 6 ECTS

Update Time: 20.05.2024 10:14