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Information
| Code | BFZ653 |
| Name | Mechanical Properties of Smooth Muscles |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. IŞIL ÖCAL |
Course Goal / Objective
According to human anatomical and physiological structure to learn the smooth muscles of the experimental animals, to isolate the rat artery aorta and uterus muscles, anesthetic and pharmacological agents to measure and record the effects of mechanical activity on the smooth muscles.
Course Content
The experimental animals used in biophysical research, the smooth muscles used in the experimental animals and the anatomy and physiology of these muscles are described.
Course Precondition
There is no prerequisite for the lesson
Resources
Biyofizik (Ferit Pehlivan), Physics Handouts, related reading, literature review and internet search
Notes
Internet Search
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Knows the smooth muscles in using the experimental animals and anatomical and physiological structures of these smooth muscles |
| LO02 | Knows the anatomical and physiological properties of smooth muscle of rat vascular aorta and uterus. |
| LO03 | Knows the mechanical properties of rat aorta muscle. |
| LO04 | Knows the dissection of the isolated aorta muscle of the rat and preparation of the preparation. |
| LO05 | Knows the mechanical properties of smooth muscles |
| LO06 | Learns the devices used to record the biomechanical parameters of smooth muscles. |
| LO07 | Records the contraction and relaxation parameters of smooth muscles |
| LO08 | Learns the agents involved in the contraction and relaxation of aorta and uterine smooth muscles |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To learn the basic information about the field | |
| PLO02 | Bilgi - Kuramsal, Olgusal | To be able to establish experimental work in laboratory | 2 |
| PLO03 | Bilgi - Kuramsal, Olgusal | To prepare a project proposal by itself | |
| PLO04 | Bilgi - Kuramsal, Olgusal | To plan an experimental research | 2 |
| PLO05 | Bilgi - Kuramsal, Olgusal | To make a report as a result of the research | 2 |
| PLO06 | Bilgi - Kuramsal, Olgusal | To be able to interpret research findings | 5 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Having analytical thinking mechanism related to the field Accessing reliable information Creating and writing a research project Study and research based on ethic values | 3 |
| PLO08 | Bilgi - Kuramsal, Olgusal | Ability to transfer the theoretical knowledge to the audience in a systematic way | 3 |
| PLO09 | Bilgi - Kuramsal, Olgusal | To have scientific thought systematic about the profession | 4 |
| PLO10 | Bilgi - Kuramsal, Olgusal | Kendi başına bir proje önerisi hazırlayabilmek |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | The smooth muscles of animals used in experimental research | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Comparison of anatomical and physiological features of rat vascular aorta and uterus smooth muscles with human smooth muscles | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Mechanical properties of rat aorta smooth muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Dissection of rat isolated aorta muscle and preparation of preparations | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 5 | Rat Instruments for measuring and recording the mechanical properties of isolated aorta muscle (contraction-relaxation) | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 6 | Pharmacological agents used to generate contraction and relaxation parameters in rat isolated aorta muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 7 | Preparation of anesthetic and physiological agents affecting rat isolated aorta preparation | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 8 | Mid-Term Exam | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
|
| 9 | Muscle contraction with different pharmacological agents in rat aorta muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 10 | Muscle relaxation with different pharmacological agents in rat aorta muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 11 | Pregnant rat formation and characteristics of the uterine muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 12 | Comparison and control activities of pregnant rat uterus muscle and normal rat uterus muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 13 | Instruments used in the measurement and recording of mechanical activities in rat uterine muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 14 | Recording of the effects of different pharmacological and anesthetic agents on mechanical activities in rat uterine muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 15 | Evaluation of the mechanical activity of rat uterus smooth muscle | Medical Physics Handouts, related reading, literature review and internet search | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Deney / Laboratuvar |
| 16 | Final Exams | Final Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
| 17 | Final Exams | Final Exams | Ölçme Yöntemleri: Yazılı Sınav, Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 2 | 2 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 28 | 28 |
| Total Workload (Hour) | 154 | ||
| Total Workload / 25 (h) | 6,16 | ||
| ECTS | 6 ECTS | ||