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Information
| Code | Trans622 |
| Name | Design and development of Diagnostic Kits |
| Term | 2024-2025 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | İngilizce |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
1 |
Course Goal / Objective
Understanding Lab on a chip systems and learning the design methods of electronic parts.
Course Content
Lab on a chip biological and chemical analysis systems with CMOS electronic circuit.
Course Precondition
No prerequisite
Resources
Yehya H. Ghallab, Wael Badawy, Lab-on-a-Chip: Techniques, Circuits, and Biomedical Applications, ARTECH HOUSE Press, 2010, ISBN 13: 978-1-59693-418-4.
Notes
Ebrahim Ghafar-Zadeh, Mohamad Sawan, CMOS Capacitive Sensors for Lab-on-Chip Applications, Springer 2010, SBN 978-90-481-3726-8 e-ISBN 978-90-481-3727-5.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Expresses the application areas of Lab-on-a-chip systems. |
| LO02 | Knows Lab-on-a-chip systems. |
| LO03 | Designs Lab-on-a-chip and CMOS circuit integration. |
| LO04 | Knows the seperation mechanism of microorganisms. |
| LO05 | Uses cell seperation systems. |
| LO06 | Designs neural activity sensing systems. |
| LO07 | Expresses, thermal, electrical and optical sensing systems. |
| LO08 | Designs compact systems for biochemical analysis. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develops and deepens the current and advanced level knowledge of translational medicine via unique thoughts or researches at a level of proficiency, find out original definitions that will bring innovation in the field of translational medicine. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Conceives the interdisciplinary interactions related to translational medicine; analyzes synthesizes and evaluates original and new thoughts. | 5 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the usage of tool, devices and instruments requiered for knowledge and technologies about translational medicine and its related disciplines. | 4 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Defines frequently used statistical methods in translational medicine and related disciplines, uses statistical softwares effectively. | |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Uses both theoretical and practical knowledge at an advanced level in the studies related to translational medicine. | 3 |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Develops a new thoughts, method and designment/application which brings innovation in translational medicine or implements a known thoughts, method and designment/application in different fields, investigates, comprehends, designs, adapts, implements an original topic. | 3 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Writes the report of his/her research which he/she participated, | |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Makes necessary investigations by using tool, devices and instrument required for knowledge and technologies about translational medicine and related disciplines at an advanced level, develops a new and creative solution (device, method, treatment, drug) for the problems. | 5 |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Uses statistical software in the field of Translational Medicine effectively, chooses statistical methods correctly, calculates and interprets correctly. | |
| PLO10 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Maintains the organization of Translational Medicine laboratories and develops solutions in case of encountering unforeseen complex situations during laboratory working hours. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Conducts scientific studies in translational medicine and related fields independently or as a team member. | |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Writes the report of his/her research in which he/she participated, publishes in a national or international reputed journal (indexing in SCI, SCI-Expanded, SSCI, or AHCI), and presents it at scientific meetings. | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Follows evidence-based practices and conducts research on professional practices that will create evidence in their field. | |
| PLO14 | Yetkinlikler - Öğrenme Yetkinliği | Applies the principles of advanced professional development and lifelong learning in the field of Translational Medicine. | |
| PLO15 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicate current developments and studies within the field to both professional and non-professional groups systematically using written, oral and visual techniques by supporting with quantitative and qualitative data. | |
| PLO16 | Bilgi - Kuramsal, Olgusal | Learns how to teach a concept, subject, phenomenon or case related to Translational Medicine. | |
| PLO17 | Belirsiz | Communicate and discuss orally, in written and visually with peers by using a foreign language at least at a level of European Language Portfolio B2 General Level. | |
| PLO18 | Yetkinlikler - Alana Özgü Yetkinlik | Audit the data gathering, interpretation, implementation and announcement stages by taking into consideration the cultural, scientific, and ethic values and uses these issues for social strategy, implementation plans and frame of quality processes. | |
| PLO19 | Yetkinlikler - Alana Özgü Yetkinlik | Knows the importance of ethical principles and ethical committees for the individual and society, acts ethically. | |
| PLO20 | Yetkinlikler - Alana Özgü Yetkinlik | Increases the awareness of society about translational medicine. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to Lab-on-a-chip systems | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 2 | Microfluidics | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 3 | Thermal, electrical and optic sensors. | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 4 | Cell structures, properties and models | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 5 | Electromechnanics of particles | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 6 | Cell manipulating fields | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 7 | Sensors and sensing mechanisms | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Repetation of the topics | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | CMOS based Lab-on-a-chip | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 10 | Microorganism detection and manipulation | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 11 | Neuronal activity detection | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 12 | Cytometry applications | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 13 | eFET, DeFET and ISFET | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 14 | Readout circuits | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 15 | pH sensing application | Reading the related part from the textbook | Öğretim Yöntemleri: Anlatım |
| 16 | Term Exams | Repetation of the topics | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Repetation of the topics | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 18 | 18 |
| Total Workload (Hour) | 114 | ||
| Total Workload / 25 (h) | 4,56 | ||
| ECTS | 5 ECTS | ||