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Information
| Code | Trans603 |
| Name | Molecular Background of Immunization |
| Term | 2024-2025 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | İngilizce |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
Prof. Dr. ASLIHAN CANDEVİR
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Aim of this course is to provide the basic knowledge about the functioning of the immune system, inflammation, immune response against infectious agents and against cancer to students. And help students understand the causes and pathogenesis of major alterations in the immune response, vaccines, and immunotherapy.
Course Content
The basic knowledge about the functioning of the immune system, inflammation, immune response against infectious agents and against cancer
Course Precondition
There is no precondition needed.
Resources
Basic Immunology: Functions and Disorders of the Immune System, Sixth Edition, Eds Abbass KA
Notes
There is no extra needed
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Describe the basic knowledge of immunological processes at a cellular and molecular level |
| LO02 | Describe the innate immune mechanisms and the early defense against pathogens |
| LO03 | Describe the structure and the function of antigen presenting cells and explain their role in antigen presentation |
| LO04 | Elucidate the genetic basis for immunological diversity and the generation of adaptive immune responses |
| LO05 | Explain the antibody recognition in adaptive immune responses and t cell mediated immunity |
| LO06 | Describe the phases and types of humoral immune responses and coordination with t cell responses |
| LO07 | List the properties of innate and adaptive immune responses and compare the key mechanisms and cellular players |
| LO08 | Identify the main mechanisms of inflammation |
| LO09 | Understand the principles governing vaccination and the mechanisms of protection against infectious diseases |
| LO10 | Understand and explain the basis of immunological tolerance, autoimmunity and transplantation |
| LO11 | Understand and explain the basis of hypersensitivity |
| LO12 | Understand and explain the immune system in cancer; tumor immunology and principles of immunotherapy |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develops and deepens the current and advanced level knowledge of translational medicine via unique thoughts or researches at a level of proficiency, find out original definitions that will bring innovation in the field of translational medicine. | 5 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Conceives the interdisciplinary interactions related to translational medicine; analyzes synthesizes and evaluates original and new thoughts. | 3 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the usage of tool, devices and instruments requiered for knowledge and technologies about translational medicine and its related disciplines. | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Defines frequently used statistical methods in translational medicine and related disciplines, uses statistical softwares effectively. | |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Uses both theoretical and practical knowledge at an advanced level in the studies related to translational medicine. | 3 |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Develops a new thoughts, method and designment/application which brings innovation in translational medicine or implements a known thoughts, method and designment/application in different fields, investigates, comprehends, designs, adapts, implements an original topic. | 3 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Writes the report of his/her research which he/she participated, | |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Makes necessary investigations by using tool, devices and instrument required for knowledge and technologies about translational medicine and related disciplines at an advanced level, develops a new and creative solution (device, method, treatment, drug) for the problems. | |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Uses statistical software in the field of Translational Medicine effectively, chooses statistical methods correctly, calculates and interprets correctly. | |
| PLO10 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Maintains the organization of Translational Medicine laboratories and develops solutions in case of encountering unforeseen complex situations during laboratory working hours. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Conducts scientific studies in translational medicine and related fields independently or as a team member. | |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Writes the report of his/her research in which he/she participated, publishes in a national or international reputed journal (indexing in SCI, SCI-Expanded, SSCI, or AHCI), and presents it at scientific meetings. | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Follows evidence-based practices and conducts research on professional practices that will create evidence in their field. | |
| PLO14 | Yetkinlikler - Öğrenme Yetkinliği | Applies the principles of advanced professional development and lifelong learning in the field of Translational Medicine. | |
| PLO15 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicate current developments and studies within the field to both professional and non-professional groups systematically using written, oral and visual techniques by supporting with quantitative and qualitative data. | 5 |
| PLO16 | Bilgi - Kuramsal, Olgusal | Learns how to teach a concept, subject, phenomenon or case related to Translational Medicine. | 4 |
| PLO17 | Belirsiz | Communicate and discuss orally, in written and visually with peers by using a foreign language at least at a level of European Language Portfolio B2 General Level. | 5 |
| PLO18 | Yetkinlikler - Alana Özgü Yetkinlik | Audit the data gathering, interpretation, implementation and announcement stages by taking into consideration the cultural, scientific, and ethic values and uses these issues for social strategy, implementation plans and frame of quality processes. | |
| PLO19 | Yetkinlikler - Alana Özgü Yetkinlik | Knows the importance of ethical principles and ethical committees for the individual and society, acts ethically. | |
| PLO20 | Yetkinlikler - Alana Özgü Yetkinlik | Increases the awareness of society about translational medicine. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to the Immune System : Nomenclature, General Properties, and Components | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 2 | Innate Immunity : The Early Defense Against Infections | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 3 | Antigen Capture and Presentation to Lymphocytes : What Lymphocytes See | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 4 | Antigen Recognition in the Adaptive Immune System : Structure of Lymphocyte Antigen Receptors and Development of Immune Repertoires | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 5 | T Cell – Mediated Immunity : Activation of T Lymphocytes | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 6 | Effector Mechanisms of T Cell–Mediated Immunity : Functions of T Cells in Host Defense | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 7 | Humoral Immune Responses : Activation of B Lymphocytes and Production of Antibodies | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | homework submission | Ölçme Yöntemleri: Ödev |
| 9 | Effector Mechanisms of Humoral Immunity : Elimination of Extracellular Microbes and Toxins | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 10 | Immunologic Tolerance and Autoimmunity : Self–Nonself Discrimination in the Immune System and Its Failure | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 11 | Immunology of Tumors and Transplantation : Immune Responses to Cancer Cells and Normal Foreign Cells | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 12 | Hypersensitivity : Disorders Caused by Immune Responses | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 13 | Congenital and Acquired Immunodeficiencies : Diseases Caused by Defective Immunity | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 14 | Vaccination | Reading the topic | Öğretim Yöntemleri: Anlatım |
| 15 | Clinical Cases | Study | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 16 | Term Exams | Study | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Study | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 18 | 18 |
| Total Workload (Hour) | 114 | ||
| Total Workload / 25 (h) | 4,56 | ||
| ECTS | 5 ECTS | ||