TÜRKÇE
ENGLISH
Information
| Code | Trans565 |
| Name | Sequencing Technologies and Its Application in Oncology |
| Term | 2024-2025 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | İngilizce |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
Esra GÖV
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Having knowledge about sequencing methods, which are of great importance in genetic technologies, and their use in the field of oncology
Course Content
Features, uses and practical applications of molecular genetic methods applied in the clinic
Course Precondition
none
Resources
Molecular genetics related on Articles
Notes
Molecular geneticsrelated on Articles/Books
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | To have general knowledge about sequencing methods |
| LO02 | Can use these methods in oncology |
| LO03 | To evaluate and analysis the studies |
| LO04 | It produces solutions to errors. |
| LO05 | Learns chemicals used in methods. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develops and deepens knowledge in the field of translational medicine to the proficiency level based on bachelor-level qualifications. | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Conceives the interdisciplinary interaction in which the field is related to translational medicine | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Knows the information technologies, technical equipment, and field-specific devices and instruments at the level required by the field of Translational Medicine. | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Knows statistics as a tool that is constantly used in studies in the field of Translational Medicine, and uses relevant software effectively. | |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Uses of theoretical and practical knowledge within the field at a proficiency level. | |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Interprets the knowledge about the field by integrating the information gathered from different disciplines and formulates new knowledge. | 4 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Makes necessary investigations by using tools, devices, and instruments required for knowledge and technologies about translational medicine and related disciplines at an advanced level; develops a new and creative solution (device, method, treatment, drug) for the problems. | |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Solves the problem faced related to the field by using research methods. | |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Plans and conducts an experimental study. | |
| PLO10 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes responsibility and develops new strategic solutions as a team member in order to solve unexpected complex problems faced within the applications in the field, evaluates the results, and applies when necessary. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Conducts scientific studies in translational medicine and related fields independently or as a team member. | |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Publishes a scientific paper in a national journal or presents it at a scientific meeting. | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Evaluates knowledge and skills acquired at proficiency level in the field with a critical approach and direct the learning. | |
| PLO14 | Yetkinlikler - Öğrenme Yetkinliği | Applies the principles of advanced professional development and lifelong learning in the field of Translational Medicine. | |
| PLO15 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates current developments and studies within the field to both professional and non-professional groups systematically using written, oral and visual techniques by supporting quantitative and qualitative data. | |
| PLO16 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Communicates and discusses orally, in writing, and visually with peers by using a foreign language at least at a level of European Language Portfolio B2 General Level. | |
| PLO17 | Yetkinlikler - Alana Özgü Yetkinlik | Develops strategy, policy, and implementation plans on the issues related to the field and assess the findings within the frame of quality processes and ethics. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Basic information about molecular genetic methods used in clinical practice | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 2 | DNA/RNA isolation from pathological tissues | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 3 | liquid biopsy | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 4 | experiment stages of DNA sequence analysis | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 5 | Next generation sequencing | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 6 | Analysis of Somatic Workflows - 1: Fresh Samples to FFPE Samples | No need for preliminary preparation | Öğretim Yöntemleri: Gösteri, Deney / Laboratuvar |
| 7 | Analysis of Somatic Workflows - 2: Circulating cell-free DNA | No need for preliminary preparation | Öğretim Yöntemleri: Gösteri, Deney / Laboratuvar |
| 8 | Mid-Term Exam | No need for preliminary preparation | Ölçme Yöntemleri: Performans Değerlendirmesi |
| 9 | NGS and Databases in Clinical Diagnostics | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Gösteri, Deney / Laboratuvar |
| 10 | Legal Issues for Data Storage | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 11 | Law on the Protection of Personal Data | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Students' presentation | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Students' presentation-1 | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Data Mining | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım |
| 15 | Clinical reporting | No need for preliminary preparation | Öğretim Yöntemleri: Anlatım, Gösteri |
| 16 | Term Exams | No need for preliminary preparation | Ölçme Yöntemleri: Ödev |
| 17 | Term Exams | No need for preliminary preparation | Ölçme Yöntemleri: Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 18 | 18 |
| Total Workload (Hour) | 114 | ||
| Total Workload / 25 (h) | 4,56 | ||
| ECTS | 5 ECTS | ||