DM0016 Epigenetic Dynamics of Stem Cell

6 ECTS - 3-0 Duration (T+A)- . Semester- 3 National Credit

Information

Code DM0016
Name Epigenetic Dynamics of Stem Cell
Term 2024-2025 Academic Year
Semester . Semester
Duration (T+A) 3-0 (T-A) (17 Week)
ECTS 6 ECTS
National Credit 3 National Credit
Teaching Language Türkçe
Level Yüksek Lisans Dersi
Type Normal
Mode of study Yüz Yüze Öğretim
Catalog Information Coordinator


Course Goal / Objective

Regulation of stem cells by epigenetic mechanisms, Reprogramming and changes in chromatin level, self-renewal, To know the differentiation mechanisms

Course Content

Stem cell potential and epigenetic regulation

Course Precondition

None

Resources

Stem cells (Biology, Types and Uses in Treatment) Alp CAN

Notes

Regenerative Medicine and Stem Cell Applications Can Özlü, Nilüfer Köylüoğlu, Aysun Özlü Publisher ‏ : ‎ Academician Bookstore (1 June 2021) Language ‏ : ‎ Turkish Paperback ‏ : ‎ 208 pages ISBN-10 ‏ : ‎ 625740150X ISBN-13 ‏ : ‎ 978-6257401500


Course Learning Outcomes

Order Course Learning Outcomes
LO01 Explains the relationship between embryo fibroblasts and cytokines.
LO02 The life cycle of the stem cell relates the issues of stress and aging.
LO03 It associates embryonic stem cells with other stem cells.
LO04 Defines embryo and fetus derived multipotent stem cells.


Relation with Program Learning Outcome

Order Type Program Learning Outcomes Level
PLO01 Beceriler - Bilişsel, Uygulamalı Understanding the fundamentals of Tissue Engineering 5
PLO02 Beceriler - Bilişsel, Uygulamalı Being well equipped with knowledge of Science, Basic Engineering and Health. 3
PLO03 Yetkinlikler - Öğrenme Yetkinliği Having capability of designing and executing experiments; examining the results and data 4
PLO04 Yetkinlikler - Öğrenme Yetkinliği Being able to design a system ,a component or a process with taking into consideration the technical, economic, enviromental, sustainability limitations 3
PLO05 Yetkinlikler - Öğrenme Yetkinliği Using Computer effectively; for computed aided design, analysis and illustrating 3
PLO06 Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği Being prone to teamwork, well communication with others, adaptability to interdisciplinary teams 3
PLO07 Bilgi - Kuramsal, Olgusal Being aware of the technical and ethical responsibility, being curious and innovative 4
PLO08 Yetkinlikler - Öğrenme Yetkinliği Ability to design , developing getting ready for use of a product or manufacturing process


Week Plan

Week Topic Preparation Methods
1 Embryo fibroblasts and cytokines Immune system preliminary research Öğretim Yöntemleri:
Anlatım, Tartışma
2 Some signaling pathways in stem cells: Wnt, Oct4, Sox2, Nanog Regulatory molecules Öğretim Yöntemleri:
Anlatım, Tartışma
3 Epigenetic control of self-renewal and differentiation Epigenetic fundamentals Öğretim Yöntemleri:
Anlatım
4 Stem cell life cycle, stress and aging Cell cycle dynamics Öğretim Yöntemleri:
Anlatım
5 Preservation of stem cell genome integrity and stress Regulatory mechanisms Öğretim Yöntemleri:
Anlatım
6 Reactive oxygen species, telomere protection Oxidative stress Öğretim Yöntemleri:
Anlatım, Tartışma, Soru-Cevap
7 DNA damage responses and stem cell aging Epigenetic modifications Öğretim Yöntemleri:
Anlatım, Soru-Cevap
8 Mid-Term Exam Subject repetition Ölçme Yöntemleri:
Ödev
9 Embryonic stem cells Prenatal stages Öğretim Yöntemleri:
Anlatım, Tartışma
10 Primitive sex cell derivatives Embryonic differentiations Öğretim Yöntemleri:
Anlatım, Tartışma
11 Induced pluripotent stem cells Pluripotency Öğretim Yöntemleri:
Anlatım, Soru-Cevap
12 Programming factors Informative molecules Öğretim Yöntemleri:
Anlatım, Beyin Fırtınası
13 The mutation load and tumor-forming ability of the stem cell Cell cycle control Öğretim Yöntemleri:
Anlatım
14 Embryo and fetus derived multipotent stem cells Stem cell sources Öğretim Yöntemleri:
Anlatım
15 Adult stem cells Tumor suppression and oncogenesis Öğretim Yöntemleri:
Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası
16 Term Exams Subject repetition Ölçme Yöntemleri:
Sözlü Sınav, Ödev
17 Term Exams Final preparation Ölçme Yöntemleri:
Ödev, Sözlü Sınav, Performans Değerlendirmesi


Student Workload - ECTS

Works Number Time (Hour) Workload (Hour)
Course Related Works
Class Time (Exam weeks are excluded) 14 3 42
Out of Class Study (Preliminary Work, Practice) 14 7 98
Assesment Related Works
Homeworks, Projects, Others 1 5 5
Mid-term Exams (Written, Oral, etc.) 1 5 5
Final Exam 1 5 5
Total Workload (Hour) 155
Total Workload / 25 (h) 6,20
ECTS 6 ECTS

Update Time: 02.07.2024 01:40