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Information
| Code | DM0015 |
| Name | Introduction to Stem Cell Biology |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator |
Course Goal / Objective
This course aims to provide a basic understanding of comprehensive information about the different biological properties of stem cells.
Course Content
Introduction and definitions, Developmental hierarchy in cells A brief overview of molecular cell biology Basic properties of stem cell Stem cell niche The life cycle of stem cells, stress, and aging.
Course Precondition
None
Resources
Stem Cell (Biology, Types and Use in Treatment) Alp CAN
Notes
Regenerative Medicine and Stem Cell Applications Can Özlü, Nilüfer Köylüoğlu, Aysun Özlü Publisher : Academician Bookstore (1 June 2021) Language : Turkish Paperback : 208 pages ISBN-10 : 625740150X ISBN-13 : 978-6257401500
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Learn about molecular biology. |
| LO02 | Have knowledge about the basic properties of stem cells. |
| LO03 | Cell division is learned. |
| LO04 | Intracellular membrane and cell receptors will be learned. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Beceriler - Bilişsel, Uygulamalı | Understanding the fundamentals of Tissue Engineering | 5 |
| PLO02 | Beceriler - Bilişsel, Uygulamalı | Being well equipped with knowledge of Science, Basic Engineering and Health. | 3 |
| PLO03 | Yetkinlikler - Öğrenme Yetkinliği | Having capability of designing and executing experiments; examining the results and data | 4 |
| PLO04 | Yetkinlikler - Öğrenme Yetkinliği | Being able to design a system ,a component or a process with taking into consideration the technical, economic, enviromental, sustainability limitations | 3 |
| PLO05 | Yetkinlikler - Öğrenme Yetkinliği | Using Computer effectively; for computed aided design, analysis and illustrating | 3 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Being prone to teamwork, well communication with others, adaptability to interdisciplinary teams | 3 |
| PLO07 | Bilgi - Kuramsal, Olgusal | Being aware of the technical and ethical responsibility, being curious and innovative | 4 |
| PLO08 | Yetkinlikler - Öğrenme Yetkinliği | Ability to design , developing getting ready for use of a product or manufacturing process |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction and definitions | Researching the basic concepts of stem cells from Internet resources | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 2 | Zygote and pre-zygote The process to the blastocyst | Research on the developmental stages of gamete mother cells | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 3 | Advanced development of ectoderm, mesoderm, and endoderm | Preliminary research on embryonic layers (leaves) | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 4 | Brief overview of molecular cell biology | Researching basic molecular mechanisms (replication, transcription, and translation) | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 5 | Chromosomes, chromatin, histones, centromeres, and telomeres | Reviewing basic genetic information | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Transcription factors | The topic of transcriptomics will be discussed | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma, Beyin Fırtınası |
| 7 | Genetic code and protein synthesis | Gene expression subject preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | topic repetition | Ölçme Yöntemleri: Sözlü Sınav, Ödev |
| 9 | Signaling molecules | Intracellular communication | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 10 | Cell membrane and intracellular receptors | Receptor and ligand interaction | Öğretim Yöntemleri: Anlatım, Tartışma |
| 11 | Basic properties of stem cells | Differences between stem cells | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Stemness, self-renewal, differentiation | Totipotency, pluripotency, and multipotency | Öğretim Yöntemleri: Anlatım, Tartışma, Soru-Cevap |
| 13 | Stem cell niche | Microenvironment interaction of stem cell | Öğretim Yöntemleri: Soru-Cevap, Anlatım, Tartışma |
| 14 | Asymmetric cell division | Cell division dynamics | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Effects on stem cell aging | Changes in gene expression | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | An overview | Ölçme Yöntemleri: Ödev, Sözlü Sınav |
| 17 | Term Exams | An overwiev | Ölçme Yöntemleri: Ödev, Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 7 | 98 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 5 | 5 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 5 | 5 |
| Final Exam | 1 | 5 | 5 |
| Total Workload (Hour) | 155 | ||
| Total Workload / 25 (h) | 6,20 | ||
| ECTS | 6 ECTS | ||