TÜRKÇE
ENGLISH
Information
| Code | BİO646 |
| Name | Advanced Medical Genetics |
| Term | 2024-2025 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. HÜSNÜ ÜMİT LÜLEYAP |
Course Goal / Objective
The aim of this course is to provide the students to have knowledge about human genome project, genetics of aging, hearing, genomics of neuromuscular diseases, apoptosis, genetics of cancer, genetic screening and to provide the students to make studies on these issues.
Course Content
Genome project, Genetic Screening, Developmental Genetics, Genetic Control of Gender, Hearing Genetics, Evolutionary genetics, transgenetics, Genetics of neuromuscular disease, immunogenetics, Genetics of aging, Cancer genetics, Genetics of metabolic diseases, Nutrigenetik, Apoptosis
Course Precondition
BİO 502 Fundamentals of medical genetics
Resources
1) M. Connor & M. Ferguson-SmithEssential Medical Genetics. Fifth Edition. Blckwell Science.
Notes
1) M. Connor & M. Ferguson-SmithEssential Medical Genetics. Fifth Edition. Blckwell Science.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Have knowledge about genome projects |
| LO02 | Have knowledge about genetic screening tests |
| LO03 | Have knowledge about developmental genetics |
| LO04 | Have knowledge about hearing genetics |
| LO05 | Knows the genetics of major neuromuscular diseases |
| LO06 | Knows immunogenetics |
| LO07 | Have knowledge about the genetics of aging |
| LO08 | Knows cancer genetics |
| LO09 | Have knowledge about metabolic diseases |
| LO10 | Knows apoptosis (programmed cell death) |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | To make and interpret Medical Genetics, Molecular Genetics and Cytogenetic analyzes | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | To have information about genetic diseases | 4 |
| PLO03 | Bilgi - Kuramsal, Olgusal | To have knowledge of Molecular Cell Biology | 3 |
| PLO04 | Bilgi - Kuramsal, Olgusal | To apply fluorescence in-situ hybridization (FISH) technique | |
| PLO05 | Bilgi - Kuramsal, Olgusal | To make DNA isolation and PCR of all kinds of tissue | 3 |
| PLO06 | Bilgi - Kuramsal, Olgusal | To make cell culture of all kinds of tissue (blood, amniotic fluid, chorionic villus biopsy) | 3 |
| PLO07 | Bilgi - Kuramsal, Olgusal | To do cytogenetic analysis by recognizing human chromosomes separately | 5 |
| PLO08 | Bilgi - Kuramsal, Olgusal | To make QF-PCR and to interpret the results | 3 |
| PLO09 | Bilgi - Kuramsal, Olgusal | To have the knowledge and skills to teach Medical Biology and Genetics Courses in Medical Faculties | 5 |
| PLO10 | Bilgi - Kuramsal, Olgusal | To write and implement a research project on his/her own | 3 |
| PLO11 | Bilgi - Kuramsal, Olgusal | To write an article by collecting the information obtained at the end of the research | 3 |
| PLO12 | Yetkinlikler - Öğrenme Yetkinliği | To organize laboratory courses of Medical Biology and Genetics courses at undergraduate level | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Genome project | Slide preparation | Öğretim Yöntemleri: Alıştırma ve Uygulama, Soru-Cevap |
| 2 | Genetic Screening | Slide preparation | Öğretim Yöntemleri: Tartışma, Alıştırma ve Uygulama |
| 3 | Developmental Genetics | Slide preparation | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 4 | Genetic Control of Gender | Slide preparation | Öğretim Yöntemleri: Anlatım |
| 5 | Hearing Genetics | Slide preparation | Öğretim Yöntemleri: Anlatım |
| 6 | Evolutionary genetics | Slide preparation | Öğretim Yöntemleri: Anlatım, Tartışma |
| 7 | Transgenetics | Slide preparation | Öğretim Yöntemleri: Anlatım, Bireysel Çalışma |
| 8 | Mid-Term Exam | Preparation of multiple-choice questions | Öğretim Yöntemleri: Soru-Cevap, Tartışma, Beyin Fırtınası |
| 9 | Genetics of neuromuscular diseases | Slide preparation | Öğretim Yöntemleri: Anlatım |
| 10 | Immunogenetics | Slide preparation | Öğretim Yöntemleri: Anlatım |
| 11 | Genetics of aging | Slide preparation | Öğretim Yöntemleri: Anlatım |
| 12 | Cancer genetics | Slide preparation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | Genetics of metabolic diseases | Slide preparation | Öğretim Yöntemleri: Anlatım |
| 14 | Nutrigenetik | Slide preparation | Öğretim Yöntemleri: Anlatım |
| 15 | Apoptosis | Slide preparation | Öğretim Yöntemleri: Soru-Cevap, Anlatım |
| 16 | Term Exams | Preparation of multiple-choice questions | Ölçme Yöntemleri: Sözlü Sınav |
| 17 | Term Exams | Preparation of multiple-choice questions | Ölçme Yöntemleri: Yazılı Sınav, Sözlü Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 3 | 42 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 3 | 42 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 4 | 8 | 32 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 2 | 2 |
| Final Exam | 1 | 2 | 2 |
| Total Workload (Hour) | 120 | ||
| Total Workload / 25 (h) | 4,80 | ||
| ECTS | 5 ECTS | ||