TÜRKÇE
ENGLISH
Information
| Code | FAR504 |
| Name | |
| Term | 2024-2025 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. NURAN ÖĞÜLENER |
| Course Instructor |
Prof. Dr. NURAN ÖĞÜLENER
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
It is intended to explain the Mechanisms of Action of Drugs and the Concept of Receptors.
Course Content
Non-receptor drug action mechanisms, receptor concept, some specific receptors, second messengers, drug-receptor interactions
Course Precondition
None
Resources
1. Basic and Clinical Pharmacology, Katzung BG, Masters SB, Trevor AJ. 12th Edition, 2012 2. Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Kayaalp S, 12. Baskı, 2009
Notes
Goodman and Gilmans The Pharmacological Basis of Therapeutics, Edit. JG Hardman, LE Limbird, Tenth Edition, McGrav Hill, 2001, ISBN 0-07-135469-7
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | To have knowledge about drug action mechanisms |
| LO02 | To have knowledge about receptor structures |
| LO03 | Knowing the types of receptors |
| LO04 | Knowing post-receptor events |
| LO05 | To have knowledge about drug-receptor interactions |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Ability to use the concepts of pharmacology, pharmacokinetics and pharmacodynamics | 4 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Establishes relationships between drug effects, mechanisms of action, and drug interactions | 4 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the side effects and toxic effects of drugs | 4 |
| PLO04 | Yetkinlikler - Alana Özgü Yetkinlik | Uses an experimental setup for an in vitro or in vivo pharmacological study | |
| PLO05 | Bilgi - Kuramsal, Olgusal | Follows scientific literature related to his/her field | 3 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes part in the design, maintenance and analysis of data of a research related to his/her field. | |
| PLO07 | Bilgi - Kuramsal, Olgusal | Is aware of the importance of scientific research ethics. | |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Expresses scientific thought analytically and establishes hypotheses. | |
| PLO09 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes part in the statistical evaluation of data. | |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Aware of the importance of rational drug use | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Mechanisms of action of drugs and general definitions | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Tartışma |
| 2 | Introduction to non-receptor drug mechanisms of action | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 3 | Ion channels | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Beyin Fırtınası |
| 4 | Enzymes | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Tartışma |
| 5 | Transport molecules and others | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 6 | Definition of the receptor concept, structures, types and general properties | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Tartışma |
| 7 | Ion channel receptors | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | Should be study to textbooks and presentations | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Structure and properties of G-proteins | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Tartışma |
| 10 | G-protein receptors | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Tartışma |
| 11 | Secondary messengers: 1) cAMP | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | Secondary messengers: 2) cGMP | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | Secondary messengers: 3) DAG and IP3 | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | Tyrosine kinase receptors | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | Theories of drug-receptor interactions | The subject should be reviewed from the textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası, Tartışma |
| 16 | Term Exams | Should be study to textbooks and presentations | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Should be study to textbooks and presentations | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 9 | 9 |
| Final Exam | 1 | 20 | 20 |
| Total Workload (Hour) | 113 | ||
| Total Workload / 25 (h) | 4,52 | ||
| ECTS | 5 ECTS | ||