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Information
| Code | FAR641 |
| Name | Central Nervous System I |
| Term | 2024-2025 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. FAZİLET AKSU |
| Course Instructor |
Doç. Dr. OLCAY KIROĞLU
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
The aim of this course is to teach advanced concepts related to the pharmacology of the central nervous system, to provide students with a more detailed understanding of the roles of specific functioning neurotransmitters in brain functioning, to give detailed information about the drugs that affect these neurotransmitter systems and are used in central nervous system diseases and to develop their skills in their experimental use.
Course Content
To teach advanced concepts related to the pharmacology of the central nervous system and autonomic nervous system, to provide a more detailed understanding of the roles of specific functioning neurotransmitters in the functioning of the brain and peripheral nerves, to give detailed information about the drugs that affect these neurotransmitter systems and are used in central nervous system diseases and to develop their skills in their experimental use.
Course Precondition
None
Resources
Fundamentals of Psychopharmacology, Brain E. Leonard, 3. Edit, Wiley, 2003. Tıbbi Farmakoloji, Oğuz Kayaalp, Hacettepe-Taş Yayınları, 2005 The Pharmacological Basis of Therapeutics, Goodman and Gilman, McGraw Hill, 2011
Notes
Fundamentals of Psychopharmacology, Brain E. Leonard, 3. Edit, Wiley, 2003. Tıbbi Farmakoloji, Oğuz Kayaalp, Hacettepe-Taş Yayınları, 2005 The Pharmacological Basis of Therapeutics, Goodman and Gilman, McGraw Hill, 2011
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Advanced knowledge of neurotransmission |
| LO02 | To understand autonomic and central nervous system functions and drugs affecting these functions |
| LO03 | To adopt advanced pharmacokinetic, pharmacodynamic and pharmacogenetic concepts related to drugs used in neuropsychiatric and neurodegenerative diseases |
| LO04 | To be able to read, understand and interpret the scientific literature in the field of neuropharmacology and to be able to produce projects using what they have learned |
| LO05 | To have knowledge and skills about the experimental use of drugs related to neuropharmacology |
| LO06 | To have knowledge about new drugs with potential use in neuropharmacology by screening clinical trials |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Beceriler - Bilişsel, Uygulamalı | Discusses the mechanisms of action, side effects, and toxic effects of drugs. | 4 |
| PLO02 | Beceriler - Bilişsel, Uygulamalı | Explains drug effects, drug interactions and effects on organ systems with a systematic approach | 4 |
| PLO03 | Yetkinlikler - Alana Özgü Yetkinlik | Plans, implements and finalizes a scientific project | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Recognize the research areas and research techniques of pharmacology | |
| PLO05 | Yetkinlikler - Alana Özgü Yetkinlik | Comparatively examines and compiles scientific articles in the field of pharmacology. | 3 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Prepares the experimental setup for an in vitro or in vivo pharmacological study and solves problems. | |
| PLO07 | Yetkinlikler - Alana Özgü Yetkinlik | He/she transforms the data obtained from the research project into a scientific research article. | |
| PLO08 | Yetkinlikler - Alana Özgü Yetkinlik | Evaluates drug use and its effects in society due to his/her knowledge about drugs. | 4 |
| PLO09 | Bilgi - Kuramsal, Olgusal | Explain clinical phase studies in drug development. | |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Evaluates and interprets study data statistically. | |
| PLO11 | Beceriler - Bilişsel, Uygulamalı | contributes to public health with its awareness of rational drug use. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Neurotransmission: Autonomic and somatic nervous systems Neurotransmission: Central Nervous System | Pharmacology textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Muscarinic receptor agonists and antagonists Anticholinesterase agents | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Drugs affecting the neuromuscular junction and autonomic ganglia Adrenergic Agonists and Antagonists | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Serotonin and Dopamine Treatment of Depression and Anxiety | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Psychosis and Mania Treatment Sedative Hypnotics | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Opioidergic System Pharmacology Pain and Analgesia | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | General Anesthetics Local Anesthetics | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Reading textbooks | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Epilepsy Treatment Stroke Treatment | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Drugs Used in the Treatment of Neurodegenerative Diseases | Reading textbooks | Öğretim Yöntemleri: Anlatım, Tartışma, Soru-Cevap |
| 11 | Substance Abuse Treatment | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | Pharmacogenetic Approach to Neuropharmacology | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | Experimental Methods in Neuropharmacology | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | Clinical Trials in Neuropharmacology | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | Article study on neuropharmacology | Reading textbooks | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 16 | Term Exams | Reading textbooks | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Reading textbooks | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 5 | 70 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 1 | 1 |
| Final Exam | 1 | 1 | 1 |
| Total Workload (Hour) | 100 | ||
| Total Workload / 25 (h) | 4,00 | ||
| ECTS | 4 ECTS | ||