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| Unit | INSTITUTE OF NATURAL AND APPLIED SCIENCES |
| BIOLOGY (PhD) | |
| Code | BY010 |
| Name | Proteomics |
| Term | 2025-2026 Academic Year |
| Term | Spring |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. HATİCE GÜVENMEZ |
| Course Instructor |
The current term course schedule has not been prepared yet. Previous term groups and teaching staff are shown.
|
Course Goal / Objective
Teaching the basic structure of proteins, function of proteins, protein-protein interactions and current proteomic applications
Course Content
The basic structure and functions of proteins and proteomics studies
Course Precondition
None
Resources
Protein Methods
Notes
Current Literatures
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Describes protein structure and functions |
| LO02 | Explanations amino acid and protein diversity |
| LO03 | Gives a detailed explanation about the proteome |
| LO04 | Explanations with an example the complex connection between transcriptom and proteome |
| LO05 | Explanations proteome analysis |
| LO06 | describes current proteomic applications |
| LO07 | Describes one-dimensional PAGE techniques |
| LO08 | Describes two-dimensional electrophoresis techniques |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Based on the qualifications of the graduate, it develops and deepens the current and advanced knowledge in the field with original thought and / or research at the level of expertise and reaches the original definitions that will bring innovation to the field. | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Evaluates, uses and transfers new information in the field with a systematic approach. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Develops a new idea, method, design and / or application that brings innovation to the field, or applies a known idea, method, design and / or application to a different field, researches, comprehends, designs and applies an original topic. | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Gains high level skills in using research methods in the field studies. | 3 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Makes critical analysis, synthesis and evaluation of new and complex thoughts. | 3 |
| PLO06 | Bilgi - Kuramsal, Olgusal | Extends the boundaries of knowledge in the field by publishing at least one scientific paper in national and / or international refereed journals and / or producing or interpreting an original work. | |
| PLO07 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Examines and develops the social relations and the norms that direct these relations from a critical point of view. | |
| PLO08 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Defends his / her original opinions in discussing the subjects in his / her field with experts, and establishes an effective communication showing his / her competence in his / her field. | 3 |
| PLO09 | Yetkinlikler - Öğrenme Yetkinliği | Introducing scientific, technological, social or cultural advances in the field; It contributes to the process of being a society of knowledge and sustaining it. | |
| PLO10 | Yetkinlikler - Öğrenme Yetkinliği | It contributes to the solution of social, scientific, cultural and ethical problems encountered in the field and supports the development of these values. | 3 |
| PLO11 | Beceriler - Bilişsel, Uygulamalı | Develops new ideas and methods related to the field by using high level mental processes such as creative and critical thinking, problem solving and decision making. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Proteins | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Structure of proteins | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 3 | surface of protein | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 4 | Diversity of amino acids | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | proteome | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 6 | The connection between the transcriptome and proteome | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 7 | Genetic code is not universal | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 8 | Mid-Term Exam | an overview | Ölçme Yöntemleri: Sözlü Sınav, Performans Değerlendirmesi |
| 9 | The connection between cell proteome and biochemistry | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | One-dimensionel polyacrylamide gel electrophoresis | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösterip Yaptırma, Grup Çalışması |
| 11 | Proteins visualization procedures | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Preparation of cellular and subcellular extracts | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 13 | Homogenization of mammalian tissue | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | 2-dimensional electrophoresis | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | microchips in proteomic applications | reading current lecture notes, related papers,and searching internet | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Beyin Fırtınası |
| 16 | Term Exams | an overview | Ölçme Yöntemleri: Sözlü Sınav, Performans Değerlendirmesi |
| 17 | Term Exams | an overview | Ölçme Yöntemleri: Sözlü Sınav, Performans Değerlendirmesi |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 6 | 84 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 2 | 6 | 12 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 12 | 12 |
| Total Workload (Hour) | 142 | ||
| Total Workload / 25 (h) | 5,68 | ||
| ECTS | 6 ECTS | ||