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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| Code | FAR508 |
| Name | Biochemistry and Medical Significance of Polyphenols |
| Term | 2025-2026 Academic Year |
| Term | Fall and Spring |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. CEMİL GÖÇMEN |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
It is aimed to teach the biochemistry of polyphenols, their use in experimental studies and their pathophysiology and to provide these evaluation skills for the development of new drugs in medical treatment.
Course Content
TO PROVIDE THE SKILLS TO USE IT IN EXPERIMENTAL STUDIES BY CONSIDERING THE IMPORTANCE AND ROLE OF PURINERGIC NEUROTRANSMISSION IN THE NERVOUS SYSTEM AND ITS PHYSIOPATHOLOGY
Course Precondition
None
Resources
Rasyonel Tedavi Yönünden Tıbbi Farmakoloji-Oğuz KAYAALP Katzung and Trevor’s Pharmacology Goodman &Gilman´s The Pharmacological Basis of Therapeutics
Notes
Scientific Literature
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Knows the biochemistry of polyphenols and their contribution to medical treatment. |
| LO02 | Knows the place and importance of polyphenols in antioxidant capacity. |
| LO03 | Knows its interaction with free radicals. |
| LO04 | Knows experimental models related to the use of polyphenols in medical therapy. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Ability to use the concepts of pharmacology, pharmacokinetics and pharmacodynamics | 1 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Establishes relationships between drug effects, mechanisms of action, and drug interactions | 1 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Explains the side effects and toxic effects of drugs | 1 |
| PLO04 | Yetkinlikler - Alana Özgü Yetkinlik | Uses an experimental setup for an in vitro or in vivo pharmacological study | |
| PLO05 | Bilgi - Kuramsal, Olgusal | Follows scientific literature related to his/her field | 2 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes part in the design, maintenance and analysis of data of a research related to his/her field. | |
| PLO07 | Bilgi - Kuramsal, Olgusal | Is aware of the importance of scientific research ethics. | |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Expresses scientific thought analytically and establishes hypotheses. | |
| PLO09 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Takes part in the statistical evaluation of data. | |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Aware of the importance of rational drug use | 1 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | INTRODUCTION TO THE PURINERGIC SYSTEM | READING BOOKS AND LITERATURE | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 2 | AUTONOMIC NEUROMUSCULAR TRANSMISSION CENTRAL NERVOUS SYSTEM PURINERGIC RECEPTORS AND THEIR SUBTYPES AND NEUROTRANSMISSION STORAGE, RELEASE AND DESTRUCTION OF ATP | READING BOOKS AND LITERATURE | Öğretim Yöntemleri: Anlatım |
| 3 | PATHOPHYSIOLOGY OF PURINERGIC NEUROTRANSMISSION IN AUTONOMIC GANGLIONS | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 4 | SENSORY NEURONS AND PURINERGIC NEUROTRANSMISSION | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 5 | THE ROLE OF PURINERGIC NEUROTRANSMISSION IN BEHAVIORAL STUDIES | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 6 | NEURON-GLIA INTERACTIONS OF PURINERGIC NEUROTRANSMISSION | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 7 | THE ROLE OF PURINERGIC NEUROEFFECTOR TRANSMISSION IN EXOCRINE GLANDS AND ENDOCRINE CELLS | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 8 | Mid-Term Exam | Reading Books and Literature | Ölçme Yöntemleri: Ödev |
| 9 | THE ROLE OF PURINERGIC NEUROTRANSMISSION IN THE UROGENITAL SYSTEM AND PHYSIOPATHOLOGY | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 10 | RELATIONSHIP OF PURINERGIC NEUROTRANSMISSION WITH COPPER CHELATORS | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 11 | THE ROLE AND PHYSIOPATHOLOGY OF PURINERGIC NEUROTRANSMISSION IN THE GASTROINTESTINAL SYSTEM | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 12 | MODULATION OF PURINERGIC NEUROTENSENSITION BY THIOL AMINOACIDS | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 13 | THE ROLE AND PHYSIOPATHOLOGY OF PURINERGIC NEUROTRANSMISSION IN THE GASTROINTESTINAL SYSTEM II | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 14 | THE ROLE AND PHYSIOPATHOLOGY OF PURINERGIC NEUROTRANSMISSION IN THE RESPIRATORY SYSTEM | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 15 | REVIEW OF CLINICAL STUDIES ON PURINERGIC NEUROTRANSMISSION | Reading Books and Literature | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 16 | Term Exams | Reading Books and Literature | Ölçme Yöntemleri: Sözlü Sınav |
| 17 | Term Exams | Reading Books and Literature | Ölçme Yöntemleri: Ödev |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 2 | 10 | 20 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 10 | 10 |
| Final Exam | 1 | 10 | 10 |
| Total Workload (Hour) | 96 | ||
| Total Workload / 25 (h) | 3,84 | ||
| ECTS | 4 ECTS | ||