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Information
| Unit | INSTITUTE OF MEDICAL SCIENCES |
| PEDIATRIC ONCOLOGY (MASTER) (WITH THESIS) | |
| Code | PEDO507 |
| Name | Stem Cell Mobilization |
| Term | 2025-2026 Academic Year |
| Term | Spring |
| Duration (T+A) | 3-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. SERHAN KÜPELİ |
| Course Instructor |
The current term course schedule has not been prepared yet.
|
Course Goal / Objective
The aim is to teach students how to mobilize CD34-positive cells necessary for stem cell transplantation, as well as donor selection, collection, and storage of cells.
Course Content
This course will cover how to mobilize the CD34-positive cell range necessary for stem cell transplantation, donor selection, and cell storage and preservation.
Course Precondition
Students are expected to have basic knowledge of stem cell transplantation.
Resources
Çukurova Pediatri Kitabı (ed: Serhan Küpeli), 2025, Ankara Kan ve Kemik İliği Transplantasyonu Klinik Kılavuzu (eds: Abutalip SA, Hari P), 2019, Anakara.
Notes
Additional readings will be shared as part of the course.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | It lists the basic principles of stem cell mobilization. |
| LO02 | It describes the conditions for good stem cell yield. |
| LO03 | It describes the mobilization principles in autologous transplantation. |
| LO04 | This explains the necessity of using plerixaphore. |
| LO05 | It lists the principles for using GCSF in mobilization. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Belirsiz | They gain expertise in donor selection. | 3 |
| PLO02 | Belirsiz | During the stem cell transplantation process, the most suitable graft is selected. | |
| PLO03 | Belirsiz | It lists the characteristics of donors according to the type of stem cell transplant. | |
| PLO04 | Belirsiz | It explains the concepts of haploidentical and allogeneic transplantation. | 3 |
| PLO05 | Belirsiz | It lists the principles for collecting stem cells from cord blood. | |
| PLO06 | Belirsiz | This describes the steps involved in collecting CD34 cells from peripheral blood. | |
| PLO07 | Belirsiz | It describes the necessary conditions for collecting stem cells from bone marrow. | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Definition of stem cell mobilization | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 2 | Selection of a donor suitable for mobilization | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 3 | Characteristics of good donor | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 4 | Mobilisation in AHSCT | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 5 | Mobilisation in allo-HSCT | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 6 | mobilisation in haplo-HSCT | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 7 | Non-related donor transfers and mobilization | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 8 | Mid-Term Exam | Review of course materials | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Use of GCSF | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 10 | Importnce of CD34 number | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 11 | Number of mononuclear cells | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 12 | use of plerixafor | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 13 | Countin the stem cells | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 14 | Purification of the product | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 15 | Storage of the product | Review of relevant textbooks and resources. | Öğretim Yöntemleri: Anlatım |
| 16 | Term Exams | Review of course materials | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Review of course materials | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 10 | 5 | 50 |
| Out of Class Study (Preliminary Work, Practice) | 10 | 5 | 50 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 5 | 5 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 5 | 5 |
| Final Exam | 1 | 10 | 10 |
| Total Workload (Hour) | 120 | ||
| Total Workload / 25 (h) | 4,80 | ||
| ECTS | 5 ECTS | ||