TÜRKÇE
ENGLISH
Information
| Unit | FACULTY OF PHARMACY |
| PHARMACY PR. | |
| Code | ECF414 |
| Name | Pharmaceutical Toxicology Laboratory |
| Term | 2019-2020 Academic Year |
| Semester | 8. Semester |
| Duration (T+A) | 0-3 (T-A) (17 Week) |
| ECTS | 2 ECTS |
| National Credit | 1.5 National Credit |
| Teaching Language | Türkçe |
| Level | Belirsiz |
| Type | Normal |
| Label | C Compulsory |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Doç. Dr. HACER SİNEM BÜYÜKNACAR |
| Course Instructor |
Doç. Dr. Göksun DEMİREL
(Bahar)
(A Group)
(Ins. in Charge)
Doç. Dr. Göksun DEMİREL (Bahar) (B Group) (Ins. in Charge) |
Course Goal / Objective
This course aims to provide the experience on toxicological analysis and the measurement of levels of drugs in biological samples obtained from poisoning cases.
Course Content
Demonstration (practical approaches in toxicology, classification of poisons according to isolation techniques; isolation techniques of poisons; collection, storage and use of samples; preparation of samples; quantitative and qualitative analysis methods of toxic substances; experimental animals); isolation of acidic and alkaline drugs that cause poisoning by extraction from biological material, identification by primary direct tests and chromatographic methods and evaluation of their toxicity, evaluation of their toxicity by spectrophotometric method;
Course Precondition
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Students are well informed for the theoretic information on the basic toxicological analysis. |
| LO02 | Students isolate toxic substances from the biological samples by extraction. |
| LO03 | Students perform the primer direct tests of toxic substances in the biological samples. |
| LO04 | Students can identify toxic substances in the biological samples by chromatographic methods. |
| LO05 | Students run quantitative analysis of toxic substances in the biological samples by spectrophotometric method. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | - | Have sufficient knowledge in pharmaceutical field and develop the knowledge gained. | |
| PLO02 | - | Applies the profession in accordance with the existing laws and regulations,gains awareness of professional and ethical responsibility. | |
| PLO03 | - | It serves the society as a pharmacist who is loyal to Atatürk's principles and reforms, equipped with Universal Knowledge, who uses Turkish correctly and knows at least one foreign language. | |
| PLO04 | - | Communicates effectively both orally and in writing. | |
| PLO05 | - | External appearance, attitude, attitude and behavior, with professional identity, role model and society becomes an example to colleagues. | |
| PLO06 | - | Provides consultancy services to patients, community and health care personnel with a wide range of information on the drug,evaluates advanced knowledge and skills with a critical approach. | |
| PLO07 | - | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | |
| PLO08 | - | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | |
| PLO09 | - | Interprets information about current health and treatment problems. Plays an active role in community health. | |
| PLO10 | - | Pharmacy integrates and develops professional knowledge with information from different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | |
| PLO11 | - | Students will be able to use the concepts and applications of basic sciences and basic medical sciences effectively in the field of Medicine and pharmacy and have the experience of working with these health sciences. | |
| PLO12 | - | Acquires basic information about diseases, adopts and applies rational drug use on all drugs that affect systems. | |
| PLO13 | - | By learning the basics of Clinical Pharmacy,will have the knowledge and skills to help provide drug/patient oriented pharmacy applications and individualized Pharmaceutical Care. | |
| PLO14 | - | It plays a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Demonstration (Introduction, Extraction, Chromatography, Spectrophotometer) | Textbooks | |
| 2 | Demonstration (Experimental Animals) | Textbooks | |
| 3 | Isolation of acidic drugs that cause poisoning often from biological sample, determination by basic recognition tests and thin layer chromatography | Textbooks | |
| 4 | Isolation of alkaline drugs that cause poisoning often from biological sample, determination by basic recognition tests and thin layer chromatography | Textbooks | |
| 5 | Quantitative determination of analgesic drugs (salicylates) which cause poisoning frequently - basic identification tests in biological sample and qualitative and spectrophotometric methods | Textbooks | |
| 6 | Determination of qualitative and quantitative paracetamol in plasma | Textbooks | |
| 7 | Evaluation of Qualitative Determinations and Toxicity of Volatile Poisons by Micro-diffusion Method in Biological Materials | Textbooks | |
| 8 | Mid-Term Exam | Exam | |
| 9 | Determination of Metallic Poisons and Toxicities in Biological Materials | Textbooks | |
| 10 | Determination of Food Additives in Different Food Groups | Textbooks | |
| 11 | Unknown Sample Analysis | Textbooks | |
| 12 | Introduction of advanced toxicology experiments | Textbooks | |
| 13 | Presentation and Discussion of Poisoning Cases by Students-1 | Textbooks | |
| 14 | Presentation and Discussion of Poisoning Cases by Students-2 | Textbooks | |
| 15 | Presentation and Discussion of Poisoning Cases by Students-3 | Textbooks | |
| 16 | Term Exams | Final Exam | |
| 17 | Term Exams | Final Exam |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Midterm Exam | 100 | 20 |
| General Assessment | ||
| Midterm / Year Total | 100 | 20 |
| 1. Final Exam | - | 80 |
| Grand Total | - | 100 |