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Information
| Unit | FACULTY OF PHARMACY |
| PHARMACY PR. | |
| Code | ECS504 |
| Name | Pharmacogenetics |
| Term | 2021-2022 Academic Year |
| Semester | 10. Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 3 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Lisans Dersi |
| Type | Normal |
| Label | E Elective |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. FATMA AYDINOĞLU |
| Course Instructor |
Prof. Dr. FATMA AYDINOĞLU
(Bahar)
(A Group)
(Ins. in Charge)
|
Course Goal / Objective
Describe to pharmacogenetic, personalize therapy and evaluate and explain to the role of genetic varieties on pharmacokinetic and pharmacodynamic characteristics, drug interactions and pharmacogenetic in clinic
Course Content
Genetic and environmental factors in individual variability, pharmacogenetic and individual therapy, the role of genetic factors in the pharmacokinetic/pharmacodinamic properties, the effect of genetic factors in individual drug responses, gene therapy
Course Precondition
Resources
Notes
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explain to pharmacogenetic and personalized therapy |
| LO02 | Explain the contribution of genetic and environmental factors in interpersonal variability in responses to drugs |
| LO03 | Explain the mechanism of genetic factors in changes in drug pharmacokinetics |
| LO04 | To explain the alterations of drug pharmacodynamic due to genetic factors |
| LO05 | Explain to the possible enzyme polymorphism caused pharmacokinetic alterations |
| LO06 | Explain to importance of pharmacogenetic in personalized therapy |
| LO07 | Explain to pharmacogenetic in clinical trials and pharmacogenetic tests |
| LO08 | Describe to current studies in pharmacogenetic |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | - | Have sufficient knowledge in pharmaceutical field and develop the knowledge gained. | 5 |
| PLO02 | - | Applies the profession in accordance with the existing laws and regulations,gains awareness of professional and ethical responsibility. | 0 |
| PLO03 | - | It serves the society as a pharmacist who is loyal to Atatürk's principles and reforms, equipped with Universal Knowledge, who uses Turkish correctly and knows at least one foreign language. | 5 |
| PLO04 | - | Communicates effectively both orally and in writing. | 3 |
| PLO05 | - | External appearance, attitude, attitude and behavior, with professional identity, role model and society becomes an example to colleagues. | 0 |
| PLO06 | - | Provides consultancy services to patients, community and health care personnel with a wide range of information on the drug,evaluates advanced knowledge and skills with a critical approach. | 5 |
| PLO07 | - | Possessing the knowledge of historical and current developments in the field of Pharmacy, monitoring, evaluation and application of scientific and evidence-based data, and adopting lifelong learning. | 5 |
| PLO08 | - | Have knowledge about health policies and health economics, pharmacy management and define the problems in pharmaceutical field. | 0 |
| PLO09 | - | Interprets information about current health and treatment problems. Plays an active role in community health. | 5 |
| PLO10 | - | Pharmacy integrates and develops professional knowledge with information from different disciplines and uses the acquired knowledge to improve the health level and quality of life of the community. | 0 |
| PLO11 | - | Students will be able to use the concepts and applications of basic sciences and basic medical sciences effectively in the field of Medicine and pharmacy and have the experience of working with these health sciences. | 5 |
| PLO12 | - | Acquires basic information about diseases, adopts and applies rational drug use on all drugs that affect systems. | 5 |
| PLO13 | - | By learning the basics of Clinical Pharmacy,will have the knowledge and skills to help provide drug/patient oriented pharmacy applications and individualized Pharmaceutical Care. | 0 |
| PLO14 | - | It plays a role in the evaluation and analysis of the events and cases related to the development of pharmacy profession and education. | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Evaluation of the contribution of genetic and environmental factors in interpersonal variability in responses to drugs | Reviews relevant book and literature | |
| 2 | Pharmacogenetic and personalized therapy | Reviews relevant book and literature | |
| 3 | Current studies on individual differences, pharmacogenetics and individual treatment in response to drugs | Reviews literature | |
| 4 | İnvestigation polymorphism of enzymes contributed to drug biotransformation | Reviews relevant book and literature | |
| 5 | Pharmacogenetic of trasnporter proteins | Reviews relevant book and literature | |
| 6 | Current literature on changes in genetic factors in drug pharmacokinetics | Reviews literature | |
| 7 | The alterations of drug pharmacodynamic due to genetic factors-1 | Reviews relevant book and literature | |
| 8 | Mid-Term Exam | ||
| 9 | The alterations of drug pharmacodynamic due to genetic factors-2 | Reviews relevant book and literature | |
| 10 | Current literature on changes in genetic factors in drug pharmacodinamic | Reviews literature | |
| 11 | The alterations of drug interactions due to genetic factors | Reviews relevant book and literature | |
| 12 | The importance of pharmacogenetics in personalized therapy | Reviews relevant book and literature | |
| 13 | Pharmacogenetic in clinical trials and pharmacogenetic tests | Reviews relevant book and literature | |
| 14 | Pharmacogenetic researches | Reviews literature | |
| 15 | Gene therapy and current studies | Reviews literature | |
| 16 | Term Exams | ||
| 17 | Term Exams |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Homework | 100 | 40 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 6 | 6 |
| Final Exam | 1 | 16 | 16 |
| Total Workload (Hour) | 78 | ||
| Total Workload / 25 (h) | 3,12 | ||
| ECTS | 3 ECTS | ||