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Information
| Code | ABL603 |
| Name | Forensic Molecular Biology |
| Term | 2022-2023 Academic Year |
| Semester | . Semester |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. AYŞE SERİN |
Course Goal / Objective
To understand the basic features of molecular forensic genetics and molecular forensic biology, to introduce potential forensic applications.
Course Content
Biological evidence, Laboratory anti-contamination procedures. Nuclear and mitochondrial DNA. DNA isolation, PCR, STR, SNP, sequencing, electrophoresis. Interpretation and reporting of DNA results.
Course Precondition
none
Resources
Molecular Forensics, Ralph Rapley, David Whitehouse, John Wiley and Son ltd,2007; Forensic DNA Typing, John Butler, Academic press
Notes
Current articles
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Explain the principles of inheritance and apply these to problem solving |
| LO02 | Knows potential Forensic DNA sources |
| LO03 | Knows the DNA polymorphisms used for forensic purposes. |
| LO04 | Select appropriate methodologies for the DNA analysis of biological evidence. |
| LO05 | Recognizes and uses necessary technological tools and, devices in forensic DNA analysis. |
| LO06 | Samples and analyzes biological evidence |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Develops current and advanced knowledge in forensic sciences at the level of expertise. | 3 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Comprehends the research methods related to Forensic Sciences at expertise level. | 3 |
| PLO03 | Bilgi - Kuramsal, Olgusal | Knows the importance of ethical principles for society and person. | 3 |
| PLO04 | Yetkinlikler - Alana Özgü Yetkinlik | Develops a new idea, method, design and/or application on forensic sciences. | 3 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Can write scientific articles related to Forensic Sciences. | |
| PLO06 | Yetkinlikler - Öğrenme Yetkinliği | Are capable of critical analysis, evaluation and synthesis of new and complex ideas. | 3 |
| PLO07 | Yetkinlikler - Öğrenme Yetkinliği | Follows evidence-based practices and conducts research on professional practices that will constitute evidence in his field. | 3 |
| PLO08 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Defends her/his original views when discussing the issues in her field with experts. | 3 |
| PLO09 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Can communicate with their peers, the larger scholarly community and with society in general about Forensic science area. | 3 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Contributes to the solution of social, scientific, cultural and ethical problems encountered in matters related to forensic sciences. | 3 |
| PLO11 | Yetkinlikler - Alana Özgü Yetkinlik | Discusses current developments and her/his own work with different groups in written, oral and visual formats. | 3 |
| PLO12 | Yetkinlikler - Alana Özgü Yetkinlik | Uses the knowledge and research methods obtained in the field in solving forensic cases and events. | 3 |
| PLO13 | Bilgi - Kuramsal, Olgusal | Knows the concept of expertise and forensic procedural approach. | 2 |
| PLO14 | Bilgi - Kuramsal, Olgusal | Knows crime scene investigation and evidence collection procedures | 3 |
| PLO15 | Bilgi - Kuramsal, Olgusal | Knows the concepts of crime, causes of crime and punishment. | |
| PLO16 | Bilgi - Kuramsal, Olgusal | Recognizes basic forensic medicine and forensic science applications. | 3 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | General information about the application areas of molecular biology | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | DNA extraction | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | DNA quantitation | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | amplification of STR markers | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Fragment analysis | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Data interpretation | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Mixture interpretation | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Midterm exam | Ölçme Yöntemleri: Yazılı Sınav |
|
| 9 | Mitochondrial DNA | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | DNA sequencing | reading related articles | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 11 | SNP polymorphisms | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Analysis of SNPs | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | INDEL polymorphisms | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Y-STRs | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Y-STR analysis | reading related articles | Öğretim Yöntemleri: Soru-Cevap, Tartışma |
| 16 | overall rating | reading related articles | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 17 | term exam | Ölçme Yöntemleri: Sözlü Sınav, Proje / Tasarım |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 10 | 10 |
| Final Exam | 1 | 20 | 20 |
| Total Workload (Hour) | 114 | ||
| Total Workload / 25 (h) | 4,56 | ||
| ECTS | 5 ECTS | ||