TÜRKÇE
ENGLISH
Information
| Code | BİS547 |
| Name | |
| Term | 2022-2023 Academic Year |
| Term | Spring |
| Duration (T+A) | 2-2 (T-A) (17 Week) |
| ECTS | 6 ECTS |
| National Credit | 3 National Credit |
| Teaching Language | Türkçe |
| Level | Yüksek Lisans Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
1 |
Course Goal / Objective
Obtaining basic information about survival analysis, obtaining information about censored data, comprehending the methods used to determine the factors affecting survival time
Course Content
Methods used to analyze lifespans and factors affecting them, introduction to survival analysis, time to failure, life table technique, non-parametric survival analysis, multivariate survival analysis (Cox regression)
Course Precondition
none
Resources
1. Miller, Rupert G. Survival analysis Wiley New York 1981 2. Klein, John P., 0387948295
Notes
Survival analysis : Techniques for censored and truncated data Springer New York 1997 3. Kleinbaum, D., Survival Analysis, Springer, 1996
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Decides, in which situations to use survival analysis. |
| LO02 | Selects the appropriate survival analysis method |
| LO03 | Applies statistical methods related to survival analysis correctly. |
| LO04 | Shows the differences between censoring types |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Students comprehends the fundamentals of statistical theory related to the field of health ( probability and bayesian biostatistics). | 5 |
| PLO02 | Bilgi - Kuramsal, Olgusal | Students explain demographic terminologies and statistical methods in the field of health sciences. | |
| PLO03 | Beceriler - Bilişsel, Uygulamalı | Students understand and use medical terminology. | 3 |
| PLO04 | Beceriler - Bilişsel, Uygulamalı | Students collect data from research studies, analyze, and make inferences | 5 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Students knows the system of international classification of diseases, obtain and analyze hospital statistics. | |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Students design scientific research studies in order to give response to the problem arising from health and clinical sciences | 4 |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Students select the appropriate statistical procedure for analysis , apply and make inferences. | 5 |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Students use the necessary statistical packages for analysis, if necessary write and develop software. | 5 |
| PLO09 | Beceriler - Bilişsel, Uygulamalı | Students follow the latest development in medical informatics and employ frequently used tools and methods. | |
| PLO10 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Students design health survey, determine the sampling method and conduct the survey | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Students select and use proper statistical procedure for diagnosis and in making inferences for the data in health and clinical medicine and provide consultance to clinicians in the field. | 5 |
| PLO12 | Yetkinlikler - Öğrenme Yetkinliği | Students develop the ability of critical thinking, make a conclusion with a critical approach to the evidence | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Students apply analytical procedure to frequently used survival data, multivariate procedure and regression techniques. | 5 |
| PLO14 | Yetkinlikler - İletişim ve Sosyal Yetkinlik | Students provide consulting services by using effective communication skills; take part in research teamworks; defend the ethical rules. | |
| PLO15 | Yetkinlikler - Alana Özgü Yetkinlik | Students explain the fundamental terminologies in epidemiology, guide researchers conducting field survey and clinical studies, develop methodologies in determining disease risk factor and disease burden and advise for choosing proper diagnostic test. |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to Survival Analysis | reding | Öğretim Yöntemleri: Anlatım |
| 2 | Censoring and Its Types | reading | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 3 | Survival Time Functions | reading | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 4 | Distributions used in survival analysis | reading | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | Survival Calculation Methods, Kaplan-Meier Method | reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama, Soru-Cevap |
| 6 | Survival time Calculation Methods, Life Table Method | reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama, Soru-Cevap |
| 7 | Survival Times Comparison Methods | reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama, Tartışma, Soru-Cevap |
| 8 | Mid-Term Exam | none | Ölçme Yöntemleri: Ödev |
| 9 | Risk (Hazard) Approach and Cox Regression | reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 10 | Variable selection in the Cox regression model | reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama, Soru-Cevap, Tartışma |
| 11 | Assumptions and control of the Cox regression model | reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama, Tartışma |
| 12 | Stratification in the Cox regression model | reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama |
| 13 | Examination of Cox regression residuals | reading | Öğretim Yöntemleri: Anlatım, Alıştırma ve Uygulama, Tartışma |
| 14 | Parametric survival models | reading | Öğretim Yöntemleri: Anlatım |
| 15 | applying survival analyzes on the data set and comparing the results | reading | Öğretim Yöntemleri: Alıştırma ve Uygulama, Soru-Cevap, Tartışma |
| 16 | Term Exams | none | Ölçme Yöntemleri: Ödev, Proje / Tasarım |
| 17 | Term Exams | none | Ölçme Yöntemleri: Ödev, Proje / Tasarım |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 4 | 56 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 4 | 56 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 2 | 2 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 12 | 12 |
| Final Exam | 1 | 28 | 28 |
| Total Workload (Hour) | 154 | ||
| Total Workload / 25 (h) | 6,16 | ||
| ECTS | 6 ECTS | ||