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Information
| Code | FAR635 |
| Name | Pharmacodynamic (Z) |
| Term | 2022-2023 Academic Year |
| Term | Spring |
| Duration (T+A) | 2-0 (T-A) (17 Week) |
| ECTS | 4 ECTS |
| National Credit | 2 National Credit |
| Teaching Language | Türkçe |
| Level | Doktora Dersi |
| Type | Normal |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | |
| Course Instructor |
1 |
Course Goal / Objective
The aim of the course is to teach pharmacodynamics, which deals with what drugs do to the body.
Course Content
Dose (concentration) relationship, Quantitative Investigation of the relationship between dose (concentration) and effect, Mechanisms of action of drugs, Receptors and drug-receptor relationship, G protein-coupled receptors, Ligand binding properties and selectivity of receptors, Receptor theory and agonism, Factors that modify the effect of drugs, Pharmacodynamic interactions between drugs, Pharmacokinetic interactions between drugs, Toxic effects of drugs - Plain toxic effects, Toxic effects of drugs - Special toxic effects, Drug allergy, Intolerance or hypersensitivity reactions
Course Precondition
None
Resources
1. Medical Pharmacology in terms of Rational Treatment, Kayaalp SO, Hacettepe Taş Kitapçılık, Ankara, IX. edition, 2000 2. Goodman & Gilman's. Pharmacologic Basis of Therapeutics. Hardman JG, Limbird LE, IXth edition, McGraw-Hill, New York, 1996 Pharmacology, Rang, HP, Dale, MM, Ritter, JM, Churchill Livingstone, Edinburgh, V. edition, 2003 3.Pharmacology, Rang, HP, Dale, MM, Ritter, JM, Churchill Livingstone, Edinburgh, V. edition, 2003 4.Lippincott's Illustrated Reviews: Pharmacology, Mycek MJ, Harvey RA, Champe PC, 2nd edition, 1997
Notes
Internet, library databases
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | Knows the mechanisms of action of drugs. |
| LO02 | Explain receptors and drug-receptor relationship. |
| LO03 | Learn drug-drug interactions. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Beceriler - Bilişsel, Uygulamalı | Interprets the mechanisms of action, side effects, toxic effects of drugs. | 5 |
| PLO02 | Beceriler - Bilişsel, Uygulamalı | Explain drug effects, drug interactions and effects on organ systems with a systematic approach. | 5 |
| PLO03 | Yetkinlikler - Alana Özgü Yetkinlik | Plans, implements and finalizes a scientific project | 1 |
| PLO04 | Bilgi - Kuramsal, Olgusal | Knows research areas and research techniques of pharmacology | 3 |
| PLO05 | Yetkinlikler - Alana Özgü Yetkinlik | Comparatively analysis and review scientific articles in the field of pharmacology | 3 |
| PLO06 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Prepares experimental setup and solves problems for an in vitro or in vivo pharmacological research. | 1 |
| PLO07 | Yetkinlikler - Alana Özgü Yetkinlik | Writes a scientific article by using data obtained from the research project. | 2 |
| PLO08 | Yetkinlikler - Alana Özgü Yetkinlik | Evaluates the use and effects of drugs in society. | 3 |
| PLO09 | Bilgi - Kuramsal, Olgusal | Explains clinical phases of drug development | 3 |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | Evaluates and interprets the project data statistically. | 1 |
| PLO11 | Beceriler - Bilişsel, Uygulamalı | Contributes to public health with its awareness of rational drug use. | 4 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Dose (concentration) relationship | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 2 | Quantitative Investigation of Dose (concentration)-Effect relationship | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 3 | Mechanisms of action of drugs | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 4 | Receptors and drug-receptor relationship | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 5 | G protein-coupled receptors | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 6 | Ligand binding properties and selectivity of receptors | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 7 | Receptor theory and agonism | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 8 | Mid-Term Exam | Reading, revision, research | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Factors that change the effect of medicines | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 10 | Pharmacodynamic interactions between drugs | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 11 | Pharmacokinetic interactions between drugs | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 12 | Toxic effects of drugs - Plain toxic effects | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 13 | Toxic effects of drugs - Special toxic effects | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 14 | Drug allergy | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 15 | Intolerance or Hypersensitivity reactions | Reading, research | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Tartışma |
| 16 | Term Exams | Reading, revision, research | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Reading, revision, research | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 2 | 28 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 1 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 8 | 8 |
| Final Exam | 1 | 24 | 24 |
| Total Workload (Hour) | 88 | ||
| Total Workload / 25 (h) | 3,52 | ||
| ECTS | 4 ECTS | ||