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Information
| Code | TL231 |
| Name | Medical Biochemistry |
| Term | 2024-2025 Academic Year |
| Semester | 3. Semester |
| Duration (T+A) | 3-4 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 5 National Credit |
| Teaching Language | Türkçe |
| Level | Ön Lisans Dersi |
| Type | Normal |
| Label | VK Vocational Knowledge Courses C Compulsory |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. ŞULE SULTAN MENZİLETOĞLU YILDIZ |
| Course Instructor |
Doç. Dr. SEDEFGÜL YÜZBAŞIOĞLU ARIYÜREK
(A Group)
(Ins. in Charge)
Prof. Dr. ŞULE SULTAN MENZİLETOĞLU YILDIZ (A Group) (Asst. Ins.) |
Course Goal / Objective
The main objective of the course will explain the basic methodology of the chemistry students to take on quantitative and qualitative results of the concept to teach logic.
Course Content
Basic concepts, measurement units, basic concentration calculations Errors in chemical analysis Gravimetric analysis methods Stoichiometric calculations Volumetric analysis methods Aqueous solution chemistry Equilibrium constants Neutralization titrations Buffer solutions Complex acid base systems Typical applications of neutralization titrations Examination and evaluation of data.
Course Precondition
None
Resources
Lesson Notes
Notes
Wictor W. Rodwell, David A. Bender, Kathleen M. Botham, Peter J. Kennelly, P. Anthony Weil. Harper'ın Resimli Biyokimyası, ISBN: 9789752777767, 804 sayfa, 2019 D. L., Nelson and M. M., Cox. Lehninger Biyokimyanın İlkeleri. Çeviri editörü Prof. Dr. Nedret KILIÇ, 2005, Palme Yayıncılık R, Harvey and P.C. Champe. Lippincott Biyokimya. Çevirmen: Doç.Dr. Engin Ulukaya, 2007, Nobel Tıp Kitabevi.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | List clinical biochemistry laboratory procedures. |
| LO02 | Explains the importance of enzymes in clinical diagnosis. |
| LO03 | Describe the disorders of carbohydrate metabolism. |
| LO04 | Explains the importance of plasma proteins in clinical diagnosis. |
| LO05 | Describes quality control and standardization methods in the clinical biochemistry laboratory. |
| LO06 | Lists the diagnostic laboratory determinants of acute myocardial infarction. |
| LO07 | Explain the importance of tumor markers in clinical diagnosis. |
| LO08 | Lists the biochemical analysis methods. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explains the basis of human normal structure and function | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Defines disinfection, sterilization and hygiene. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Recognizes laboratory tools and materials, lists measurement methods. | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Explains the procedures to be performed in these phases using detailed information on the preanalytical, analytical and postanalytical phases of measurements. | 5 |
| PLO05 | Bilgi - Kuramsal, Olgusal | Receives and accepts biological materials taken from the patient, prepares them for analysis and ensures that they are preserved under appropriate conditions if necessary. | |
| PLO06 | Bilgi - Kuramsal, Olgusal | Performs internal and external quality control studies of the analyzes, analyzes patient samples after applying daily control procedures, checks the results and reports to the laboratory specialist. | |
| PLO07 | Bilgi - Kuramsal, Olgusal | Performs the calibration and maintenance of laboratory equipments, have them to be calibrated and maintained and monitored by authorized persons as needed, so that they work most efficiently | 4 |
| PLO08 | Bilgi - Kuramsal, Olgusal | Determines inaduquaciesis in the laboratory | |
| PLO09 | Bilgi - Kuramsal, Olgusal | Knows the critical values and provides coordination by reporting the results to the clinician in the most appropriate and fast manner. | |
| PLO10 | Beceriler - Bilişsel, Uygulamalı | After graduation, he/she develops himself/herself and his/her career by following technological developments and critically evaluating the information he/she has learned with his/her own knowledge. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Having professional and ethical responsibility, they communicate well with colleagues, patients and physicians. | 3 |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Uses at least one foreign language to follow developments in his field and to communicate with colleagues adequately. | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Takes measures regarding health, biosafety and occupational safety in the work environment. | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to clinical biochemistry and laboratory work Collection of samples and procedures performed. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım |
| 2 | The importance of enzymes in clinical diagnosis | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Soru-Cevap |
| 3 | Disorders of carbohydrate metabolism | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar |
| 4 | The importance of plasma proteins in clinical diagnosis | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Tartışma |
| 5 | Plasma lipids and atherosclerosis. | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 6 | Quality control and standardization in clinical biochemistry laboratory | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösteri |
| 7 | Diagnostic laboratory determinants of acute myocardial infarction, Liver function tests, Bilirubin metabolism and jaundice | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 8 | Mid-Term Exam | Reading the lecture notes and power point presentation | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Kidney function tests | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar |
| 10 | Iron metabolism and anemics | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Tartışma, Örnek Olay |
| 11 | Endocrinology | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 12 | Minerals and electrolyte metabolism | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Tartışma |
| 13 | Significance of tumor markers in clinical diagnosis | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar, Beyin Fırtınası |
| 14 | Cerebrospinal fluid (CSF) biochemistry | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösterip Yaptırma |
| 15 | Quality control | Reading the lecture notes and power point presentation | Öğretim Yöntemleri: Anlatım, Gösteri, Tartışma |
| 16 | Term Exams | Reading the lecture notes and power point presentation | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Reading the lecture notes and power point presentation | Ölçme Yöntemleri: Yazılı Sınav |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 7 | 98 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 2 | 2 |
| Final Exam | 1 | 2 | 2 |
| Total Workload (Hour) | 130 | ||
| Total Workload / 25 (h) | 5,20 | ||
| ECTS | 5 ECTS | ||