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| Unit | ABDİ SÜTCÜ HEALTH SERVICES VOCATIONAL SCHOOL |
| Code | TL231 |
| Name | Medical Biochemistry |
| Term | 2024-2025 Academic Year |
| Semester | 3. Semester |
| Duration (T+A) | 3-4 (T-A) (17 Week) |
| ECTS | 5 ECTS |
| National Credit | 5 National Credit |
| Teaching Language | Türkçe |
| Level | Ön Lisans Dersi |
| Type | Normal |
| Label | VK Vocational Knowledge Courses C Compulsory |
| Mode of study | Yüz Yüze Öğretim |
| Catalog Information Coordinator | Prof. Dr. ŞULE SULTAN MENZİLETOĞLU YILDIZ |
| Course Instructor |
Doç. Dr. SEDEFGÜL YÜZBAŞIOĞLU ARIYÜREK
(Güz)
(A Group)
(Ins. in Charge)
Prof. Dr. ŞULE SULTAN MENZİLETOĞLU YILDIZ (Güz) (A Group) (Asst. Ins.) |
Course Goal / Objective
At the end of this course, students are expected to understand the functioning of biochemical metabolism and apply biochemical analyses in the diagnosis of diseases related to these.
Course Content
Sampling in clinical biochemistry, clinical enzymology, endocrinology, carbohydrate metabolism disorders, plasma proteins and lipids, liver and kidney functions, iron-mineral and electrolyte metabolism, CSF biochemistry, tumor markers and quality control and standardization in clinical biochemistry laboratories will be discussed in this course.
Course Precondition
None
Resources
Lesson Notes
Notes
Wictor W. Rodwell, David A. Bender, Kathleen M. Botham, Peter J. Kennelly, P. Anthony Weil. Harper'ın Resimli Biyokimyası, ISBN: 9789752777767, 804 sayfa, 2019 D. L., Nelson and M. M., Cox. Lehninger Biyokimyanın İlkeleri. Çeviri editörü Prof. Dr. Nedret KILIÇ, 2005, Palme Yayıncılık R, Harvey and P.C. Champe. Lippincott Biyokimya. Çevirmen: Doç.Dr. Engin Ulukaya, 2007, Nobel Tıp Kitabevi.
Course Learning Outcomes
| Order | Course Learning Outcomes |
|---|---|
| LO01 | List clinical biochemistry laboratory procedures. |
| LO02 | Explains the importance of enzymes in clinical diagnosis. |
| LO03 | Describe the disorders of carbohydrate metabolism. |
| LO04 | Explains the importance of plasma proteins in clinical diagnosis. |
| LO05 | Describes quality control and standardization methods in the clinical biochemistry laboratory. |
| LO06 | Lists the diagnostic laboratory determinants of acute myocardial infarction. |
| LO07 | Explain the importance of tumor markers in clinical diagnosis. |
| LO08 | Lists the biochemical analysis methods. |
Relation with Program Learning Outcome
| Order | Type | Program Learning Outcomes | Level |
|---|---|---|---|
| PLO01 | Bilgi - Kuramsal, Olgusal | Explains the basis of human normal structure and function | |
| PLO02 | Bilgi - Kuramsal, Olgusal | Defines disinfection, sterilization and hygiene. | |
| PLO03 | Bilgi - Kuramsal, Olgusal | Recognizes laboratory tools- materials, and measurement methods. | |
| PLO04 | Bilgi - Kuramsal, Olgusal | Explains the procedures to be performed in these phases using detailed information on the preanalytical, analytical and postanalytical phases of measurements. | 5 |
| PLO05 | Beceriler - Bilişsel, Uygulamalı | Receives and accepts biological materials taken from the patient, prepares them for analysis and ensures that they are preserved under appropriate conditions if necessary. | |
| PLO06 | Beceriler - Bilişsel, Uygulamalı | Performs internal and external quality control studies of the analyzes, analyzes patient samples after applying daily control procedures, checks the results and reports to the laboratory specialist. | |
| PLO07 | Beceriler - Bilişsel, Uygulamalı | Performs the calibration and maintenance of laboratory equipments, have them to be calibrated and maintained and monitored by authorized persons as needed, so that they work most efficiently | 4 |
| PLO08 | Beceriler - Bilişsel, Uygulamalı | Determines inaduquaciesis in the laboratory | |
| PLO09 | Bilgi - Kuramsal, Olgusal | It provides coordination by reporting critical values to the clinician in the most appropriate and rapid way. | |
| PLO10 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | After graduation, he/she develops himself/herself and his/her career by following technological developments and critically evaluating the information he/she has learned with his/her own knowledge. | |
| PLO11 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Having professional and ethical responsibility, they communicate well with colleagues, patients and physicians. | 3 |
| PLO12 | Yetkinlikler - Bağımsız Çalışabilme ve Sorumluluk Alabilme Yetkinliği | Uses at least one foreign language to follow developments in his field and to communicate with colleagues adequately. | |
| PLO13 | Yetkinlikler - Öğrenme Yetkinliği | Takes measures regarding health, biosafety and occupational safety in the work environment. | 2 |
Week Plan
| Week | Topic | Preparation | Methods |
|---|---|---|---|
| 1 | Introduction to clinical biochemistry and laboratory work Collection of samples and procedures performed. | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım |
| 2 | The importance of enzymes in clinical diagnosis | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Soru-Cevap |
| 3 | Disorders of carbohydrate metabolism | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar |
| 4 | The importance of plasma proteins in clinical diagnosis | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım, Tartışma |
| 5 | Plasma lipids and atherosclerosis. | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım, Soru-Cevap |
| 6 | Quality control and standardization in clinical biochemistry laboratory | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösteri |
| 7 | Diagnostic laboratory determinants of acute myocardial infarction, Liver function tests, Bilirubin metabolism and jaundice | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 8 | Mid-Term Exam | Repetition of topics | Ölçme Yöntemleri: Yazılı Sınav |
| 9 | Kidney function tests | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar |
| 10 | Iron metabolism and anemics | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Tartışma, Örnek Olay |
| 11 | Endocrinology | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Deney / Laboratuvar |
| 12 | Minerals and electrolyte metabolism | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım, Tartışma |
| 13 | Significance of tumor markers in clinical diagnosis | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım, Deney / Laboratuvar, Beyin Fırtınası |
| 14 | Cerebrospinal fluid (CSF) biochemistry | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım, Soru-Cevap, Gösterip Yaptırma |
| 15 | Quality control | Reading resources, lecture notes and lecture presentations | Öğretim Yöntemleri: Anlatım, Gösteri, Tartışma |
| 16 | Term Exams | Repetition of topics | Ölçme Yöntemleri: Yazılı Sınav |
| 17 | Term Exams | Repetition of topics | Ölçme Yöntemleri: Yazılı Sınav |
Assessment (Exam) Methods and Criteria
| Assessment Type | Midterm / Year Impact | End of Term / End of Year Impact |
|---|---|---|
| 1. Midterm Exam | 100 | 40 |
| General Assessment | ||
| Midterm / Year Total | 100 | 40 |
| 1. Final Exam | - | 60 |
| Grand Total | - | 100 |
Student Workload - ECTS
| Works | Number | Time (Hour) | Workload (Hour) |
|---|---|---|---|
| Course Related Works | |||
| Class Time (Exam weeks are excluded) | 14 | 7 | 98 |
| Out of Class Study (Preliminary Work, Practice) | 14 | 2 | 28 |
| Assesment Related Works | |||
| Homeworks, Projects, Others | 0 | 0 | 0 |
| Mid-term Exams (Written, Oral, etc.) | 1 | 3 | 3 |
| Final Exam | 1 | 8 | 8 |
| Total Workload (Hour) | 137 | ||
| Total Workload / 25 (h) | 5,48 | ||
| ECTS | 5 ECTS | ||